Angiotensin II Receptor-Associated Protein Proteine (AGTRAP)

AGTRAP encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. Zusätzlich bieten wir Ihnen Angiotensin II Receptor-Associated Protein Antikörper (49) und Angiotensin II Receptor-Associated Protein Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
AGTRAP 57085 Q6RW13
Ratte AGTRAP AGTRAP 298646 Q642A2
AGTRAP 11610 Q9WVK0
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Showing 3 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$6,041.49
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,244.78
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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AGTRAP Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Angiotensin II Receptor-Associated Protein (AGTRAP) Interaktionspartnern

Human Angiotensin II Receptor-Associated Protein (AGTRAP) Interaktionspartner

  1. A role for AT1 receptor-associated proteins in blood pressure regulation

  2. ATRAP, a directly interacting and functionally inhibiting molecule of AT1R (zeige AGTR1 Proteine), plays a protective role against the development of systemic insulin (zeige INS Proteine) resistance via regulatory effects on adipose tissue function.

  3. The phosphatidylinositol transfer protein (zeige PITPNA Proteine) RdgBbeta (zeige PITPNC1 Proteine) binds 14-3-3 (zeige YWHAQ Proteine) via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein ATRAP (angiotensin II type I receptor-associated protein).

  4. the GG genotype of the AGTRAP rs11121816 T/G single nucleotide polymorphism was associated with increased mortality in two cohorts of patients who had septic shock.

  5. CSF (zeige CSF2 Proteine) angiotensin II, ACE (zeige ACE Proteine), and ACE2 (zeige ACE2 Proteine) levels are decreased in neuromyelitis optica/NMO spectrum disorder patients with anti-AQP4 (zeige AQP4 Proteine) antibody, reflecting severe destruction of perivascular astrocytes

  6. Small interfering RNA significantly attenuates angiotensin II type 1 receptor (zeige AGTR1 Proteine)-stimulated inositol phosphate formation.

  7. cloned a new human gene cDNA that codes for a homolog of the murine Agtrap protein

  8. isolation of a novel protein, ARAP1 (zeige ARAP1 Proteine), which promotes recycling of angiotensin(1A) to the plasma membrane in HEK (zeige EPHA3 Proteine)-293 cells

  9. CAML (zeige CAMLG Proteine) is an important signal transducer for the actions of Ang II (zeige AGT Proteine) in regulating the calcineurin-NFAT (zeige NFATC1 Proteine) pathway and the interaction of CAML (zeige CAMLG Proteine) with ATRAP may mediate the Ang II (zeige AGT Proteine) actions in vascular physiology

Mouse (Murine) Angiotensin II Receptor-Associated Protein (AGTRAP) Interaktionspartner

  1. Renal ATRAP downregulation is involved in the onset and progression of blood pressure elevation caused by renal mass reduction, and implicates ATRAP as a therapeutic target for hypertension in chronic kidney disease.

  2. These results implied that AngII could effectively induce EpiCs to differentiate into vascular smooth muscle-like cells through the AT1 receptor.

  3. ATRAP expression in brown adipose tissue does not influence the pathogenesis of dietary obesity or metabolic disorders.

  4. Identify Atrap as a novel regulatory protein of the cardiac Ca(2+)-ATPase SERCA2a. Suggest that Atrap enhances the activity of SERCA2a and, consequently, facilitates ventricular relaxation.

  5. These results suggest that increased formation of AT1R-P2Y6R (zeige P2RY6 Proteine) heterodimers with age may increase the likelihood of hypertension induced by Ang II (zeige AGT Proteine).

  6. although erythropoiesis and blood pressure are negatively controlled through the AT1 receptor inhibition in vivo, the pathways involved are complex and distinct

  7. Distal tubule-dominant enhancement of ATRAP inhibits pathological renal sodium reabsorption and blood pressure elevation in response to high salt loading.

  8. AT1R knockout mice were less vulnerable to controlled cortical impact-induced injury.

  9. The inhibition of degradation of angiotensin II type 1 receptor (zeige AGTR1 Proteine)-associated protein (zeige BCAP31 Proteine) (ATRAP) and inactivation of AT1R-mediated p38 MAPK (zeige MAPK14 Proteine) and STAT3 (zeige STAT3 Proteine) signaling pathways, are involved cardiac hypertrophy.

  10. Activation of aortic vascular ATRAP partially inhibits the Nox4 (zeige NOX4 Proteine)/p22(phox (zeige CYBA Proteine))-ROS (zeige ROS1 Proteine)-p38MAPK (zeige MAPK14 Proteine)/JNK (zeige MAPK8 Proteine) pathway and pathological aortic hypertrophy provoked by Ang II (zeige AGT Proteine)-mediated hypertension.

Angiotensin II Receptor-Associated Protein (AGTRAP) Protein Überblick

Protein Überblick

This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit AGTRAP

  • angiotensin II receptor associated protein (AGTRAP)
  • angiotensin II receptor-associated protein (Agtrap)
  • angiotensin II, type I receptor-associated protein (Agtrap)
  • 3300002E14Rik Protein
  • AGTRAP Protein
  • AT1R Protein
  • Atrap Protein
  • D4Wsu124e Protein
  • DKFZp469M235 Protein
  • LOC100223570 Protein

Bezeichner auf Proteinebene für AGTRAP

angiotensin II receptor-associated protein , type-1 angiotensin II receptor-associated protein , Type-1 angiotensin II receptor-associated protein , AT1 receptor-associated protein , ATI receptor-associated protein , angiotensin II, type I receptor-associated protein , AT1 receptor , angiotensin II receptor, type I

GENE ID SPEZIES
419491 Gallus gallus
457954 Pan troglodytes
508521 Bos taurus
608333 Canis lupus familiaris
100174244 Pongo abelii
100223570 Taeniopygia guttata
57085 Homo sapiens
298646 Rattus norvegicus
11610 Mus musculus
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