anti-Angiotensin I Converting Enzyme 2 (ACE2) Antikörper

The protein encoded by ACE2 belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human ACE2 ACE2 59272 Q9BYF1
Anti-Maus ACE2 ACE2 70008 Q8R0I0
Anti-Ratte ACE2 ACE2 302668 Q5EGZ1
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Weitere Antikörper gegen Angiotensin I Converting Enzyme 2 Interaktionspartner

Human Angiotensin I Converting Enzyme 2 (ACE2) Interaktionspartner

  1. Overexpression of ACE2 ameliorates Abeta (zeige APP Antikörper)-induced inflammatory response by activating the ACE2/Ang-(1 (zeige ANGPT1 Antikörper)-7)/Mas (zeige MAS1 Antikörper) axis in human RPE (zeige RPE Antikörper) cells.

  2. Although further studies are required to determine how clusterin (zeige CLU Antikörper) suppresses non-specific cellular uptake in phagocytes, our data suggest that clusterin (zeige CLU Antikörper) plays a key role in the stealth effect of not only pegylated nanoparticles but also non-pegylated nanoparticles.

  3. The ACE2 G8790A polymorphism in type 2 diabetes mellitus patients was correlated with cerebral stroke, and the A allele might be a risk factor of type 2 diabetes mellitus combined with cerebral stroke.

  4. ollectrin, an ACE2 homolog with no catalytic activity, regulates blood pressure through an NO-dependent mechanism. Large body of experimental data confirmed sustained beneficial effects of ACE2/Ang-(1 (zeige ANGPT1 Antikörper)-7)/Mas (zeige MAS1 Antikörper) receptor axis activation on hypertension and vascular injury.

  5. The potential contribution of the ACE2 to cardiovascular disease progression was addressed.

  6. Serum ACE2 activity was significantly lower in acute ischemic stroke as compared to both control and stroke-alert patients, followed by an increase to control levels at three days.

  7. Here, we review the role and effects of ACE2, ACE2 activators, Ang-(1 (zeige ANGPT1 Antikörper)-7) and synthetic Mas (zeige MAS1 Antikörper) receptor agonists in the control of inflammation and fibrosis in cardiovascular and renal diseases and as counter-regulators of the ACE (zeige ACE Antikörper)-Ang II (zeige AGT Antikörper)-AT1 (zeige AGTR1 Antikörper) axis.

  8. ACE2 overexpression inhibited cell growth.

  9. Downregulation of ACE2/Ang-(1 (zeige ANGPT1 Antikörper)-7)/Mas (zeige MAS1 Antikörper) axis stimulates breast cancer metastasis through the activation of store-operated calcium entry and PAK1 (zeige PAK1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper)/Snail1 (zeige SNAI1 Antikörper) pathways.

  10. The circulating ACE2 and Ang-(1 (zeige ANGPT1 Antikörper)-7) levels were related to neither rs4646155 nor rs879922 in female or male patients.In conclusion, the rs2106809 polymorphism of the ACE2 gene may be a determinant of the circulating Ang-(1 (zeige ANGPT1 Antikörper)-7) level in female patients with hypertension, suggesting a genetic association between circulating Ang-(1 (zeige ANGPT1 Antikörper)-7) levels and ACE2 gene polymorphisms in patients with hypertension.

Mouse (Murine) Angiotensin I Converting Enzyme 2 (ACE2) Interaktionspartner

  1. Altogether, our study demonstrates that HFD feeding increases RAS activity and mediates glycemic dysregulation likely through loss of ACE2 present outside the islets but independently of changes in islet ACE2.

  2. Results suggest that angiotensin converting enzyme 2 may reduce anxiety-like behavior by activating central Mas (zeige MAS1 Antikörper) receptor that facilitate GABA release onto pyramidal neurons within the basolateral amygdala.

  3. These findings demonstrate that ACE2 plays a critical role in preventing RSV-induced lung injury, and suggest that ACE2 is a promising potential therapeutic target in the management of RSV-induced lung disease.

  4. ACE2 overexpression significantly reduced the myocardial infarction-induced increase in apoptosis, macrophage infiltration, and HMGB1 (zeige HMGB1 Antikörper) and proinflammatory cytokine expression.

  5. ACE2 regulates vascular function by modulating nitric oxide release.

  6. MAS (zeige MAS1 Antikörper) receptors mediate vasoprotective and atheroprotective effects of candesartan upon the recovery of vascular ACE2-angiotensin-(1-7)-MAS (zeige MAS1 Antikörper) axis functionality

  7. ACE2 plays a novel role in heart disease associated with obesity wherein ACE2 negatively regulates obesity-induced epicardial adipose tissue inflammation and cardiac insulin (zeige INS Antikörper) resistance.

  8. a Mas (zeige MAS1 Antikörper) receptor-mediated mechanism may stimulate pancreatic cell development

  9. ACE2 deficiency exacerbates kidney inflammation, oxidative stress and adverse renal injury in the ApoE (zeige APOE Antikörper)-mutant mice through modulation of the nephrin (zeige NPHS1 Antikörper), NOX4 (zeige NOX4 Antikörper) and TNF-alpha (zeige TNF Antikörper)-TNFRSF1A (zeige TNFRSF1A Antikörper) signaling.

  10. Hydronephrosis led to an increase of ACE (zeige ACE Antikörper) level and a decrease of ACE2 and Mas (zeige MAS1 Antikörper) receptor in the heart.

Cow (Bovine) Angiotensin I Converting Enzyme 2 (ACE2) Interaktionspartner

  1. The objective of this study was to characterize the profiles of Ang-(1-7), MAS receptor, ACE(2), NEP and PEP during the ovulatory process in cattle.

Rhesus Monkey Angiotensin I Converting Enzyme 2 (ACE2) Interaktionspartner

  1. sporadic non-synonymous substitutions reduced the level of rh-ACE2 protein expression and did not support severe acute respiratory syndrome coronavirus entry effectively

Pig (Porcine) Angiotensin I Converting Enzyme 2 (ACE2) Interaktionspartner

  1. In a pig model of acute pulmonary embolism leading to cardiac arrest, captopril infusion was associated with less mean right ventricular pressure overload after resuscitation, compared with saline infusion. The reduction in systemic and pulmonary vascular resistance associated with captopril may be by inhibiting the ACE (zeige ACE Antikörper)-Ang II (zeige AGT Antikörper)-AT1R (zeige AGTR1 Antikörper) axis and activating the ACE2/Ang-(1 (zeige ANGPT1 Antikörper)-7)/Mas (zeige MAS1 Antikörper) axis.

  2. This study produced the full-length porcine ACE2 cDNA sequence and found polyunsaturated fatty acids could downregulate the expression of ACE2.

Angiotensin I Converting Enzyme 2 (ACE2) Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Genbezeichner und Symbole assoziert mit ACE2

  • angiotensin I converting enzyme 2 (ACE2) Antikörper
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (Ace2) Antikörper
  • angiotensin I converting enzyme 2 (Ace2) Antikörper
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) Antikörper
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ace2) Antikörper
  • 2010305L05Rik Antikörper
  • ACEH Antikörper
  • zgc:92514 Antikörper

Bezeichner auf Proteinebene für ACE2

ACE-related carboxypeptidase , angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 , angiotensin-converting enzyme 2 , angiotensin-converting enzyme homolog , metalloprotease MPROT15 , peptidyl-dipeptidase A , angiotensin I converting enzyme 2 , anigotensin-converting enzyme-related carboxypeptidase , renal angiotensin-converting enzyme 2

GENE ID SPEZIES
59272 Homo sapiens
70008 Mus musculus
302668 Rattus norvegicus
418623 Gallus gallus
480847 Canis lupus familiaris
492331 Danio rerio
509235 Bos taurus
554349 Felis catus
712790 Macaca mulatta
100144303 Sus scrofa
100171441 Pongo abelii
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