anti-Angiomotin Like 2 (AMOTL2) Antikörper

AMOTL2 belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. Zusätzlich bieten wir Ihnen Angiomotin Like 2 Proteine (4) und Angiomotin Like 2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
AMOTL2 51421 Q9Y2J4
AMOTL2 65157  
AMOTL2 56332 Q8K371
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of AMOTL2 Antibody (Center) (ABIN652806) in A375 cell line lysates (35 µg/lane). AMOTL2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of AMOTL2 Antibody (Center) (ABIN652806) in mouse liver tissue lysates (35 µg/lane). AMOTL2 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Unkonjugiert ICC, IF Immunocytochemistry/Immunofluorescence: AMOTL2 Antibody  - Staining of human cell line CACO-2 shows localization to centrosome & cell junctions. 100 μL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
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Human Kaninchen Unkonjugiert WB Western blot analysis of AMOTL2 Antibody in A375 cell line lysates (35ug/lane) Western blot analysis of AMOTL2 Antibody in mouse liver tissue lysates (35ug/lane) 400 μL Anmelden zum Anzeigen 6 bis 8 Tage
538,22 €
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Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
460,95 €
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Human Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 15 bis 21 Tage
645,71 €
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Human Kaninchen HRP ELISA, WB   200 μL Anmelden zum Anzeigen 20 bis 21 Tage
800,82 €
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Human Kaninchen PE ELISA, WB   200 μL Anmelden zum Anzeigen 20 bis 21 Tage
800,82 €
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Human Kaninchen APC ELISA, WB   200 μL Anmelden zum Anzeigen 20 bis 21 Tage
800,82 €
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Human Kaninchen FITC ELISA, WB   200 μL Anmelden zum Anzeigen 20 bis 21 Tage
800,82 €
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Human Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
460,89 €
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AMOTL2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , ,


, , , , ,
Rat (Rattus)


Mouse (Murine) ,


Am meisten referenzierte anti-Angiomotin Like 2 Antikörper

  1. Human Polyclonal AMOTL2 Primary Antibody für WB - ABIN652806 : Bratt, Wilson, Troyanovsky, Aase, Kessler, Van Meir, Holmgren, Meir: Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains. in Gene 2002 (PubMed)
    Zeige alle 2 Referenzen für 652806

Weitere Antikörper gegen Angiomotin Like 2 Interaktionspartner

Zebrafish Angiomotin Like 2 (AMOTL2) Interaktionspartner

  1. Amotl2a function in the control of lateral line primordium cell proliferation is mediated together by the Hippo pathway effector Yap1 (zeige YAP1 Antikörper) and the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) effector Lef1 (zeige LEF1 Antikörper).

  2. amotL2 associates to the VE-cadherin adhesion complex where it couples adherens junctions to contractile actin fibres.

  3. We demonstrate that amotl2 knockdown in zebrafish wild-type embryos results in embryonic dorsalization, and this effect can be antagonized by co-knockdown of the dorsal inducer beta-catenin2.

  4. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

  5. Amotl2 interacts preferentially with and facilitates translocation of the phosphorylated c-Src (zeige SRC Antikörper), which may in turn regulate the membrane architecture. These data provide the first evidence that amotl2 is essential for cell movements in vertebrate embryos.

Human Angiomotin Like 2 (AMOTL2) Interaktionspartner

  1. these results provide novel insights into a dual tumor suppressive function of AMOTL2 by targeting both YAP (zeige YAP1 Antikörper) and AKT (zeige AKT1 Antikörper) in liver size control and cancer prevention

  2. study reports for the first time that USP9X (zeige USP9X Antikörper) is a deubiquitinase of Angiomotin-like 2 (AMOTL2) and that AMOTL2 mono-ubiquitination is required for YAP (zeige YAP1 Antikörper) inhibition

  3. mTORC2 (zeige CRTC2 Antikörper)-mediated phosphorylation of AMOTL2 blocks its ability to inhibit YAP (zeige YAP1 Antikörper) signaling.

  4. AmotL2 expression correlates with loss of tissue architecture in tumors from human breast and colon cancer patients.

  5. Scaffold proteins angiomotin (Amot (zeige AMOT Antikörper)) and angiomotin (zeige AMOT Antikörper)-related AmotL1 (zeige AMOTL1 Antikörper) and AmotL2 were recently identified as negative regulators of YAP (zeige YAP1 Antikörper) and TAZ (zeige TAZ Antikörper) by preventing their nuclear translocation.

  6. These results collectively suggest that the Hippo pathway negatively regulates the actin-binding activity of Amot (zeige AMOT Antikörper) family members through direct phosphorylation.

  7. These results demonstrate a role for Amotl2 in synaptic maturation and support the involvement of podosomes in this process.

  8. AMOTL2 interacts with TAZ (zeige TAZ Antikörper) and modulates transcriptional activity of TAZ (zeige TAZ Antikörper).

  9. AMOTL2 is as a novel activator of LATS2 (zeige LATS2 Antikörper).

  10. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

Mouse (Murine) Angiomotin Like 2 (AMOTL2) Interaktionspartner

  1. mTORC2 (zeige CRTC2 Antikörper)-mediated phosphorylation of AMOTL2 blocks its ability to inhibit YAP (zeige YAP1 Antikörper) signaling.

  2. AmotL2 disrupts apical-basal cell polarity and promotes tumor invasion.

  3. Amot (zeige AMOT Antikörper), Amotl1 (zeige AMOTL1 Antikörper), and Amotl2 are differentially expressed in uterine cells during the peri (zeige POSTN Antikörper)-implantation period.

  4. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

  5. Data show that MUPP1 (zeige MPDZ Antikörper) interacts with angiomotin (Amot (zeige AMOT Antikörper)), JEAP (zeige AMOTL1 Antikörper)/Amot (zeige AMOT Antikörper)-like 1 and MASCOT/Amot (zeige AMOT Antikörper)-like 2, and that all the Amot (zeige AMOT Antikörper)/JEAP (zeige AMOTL1 Antikörper) family proteins also interacted with Patj (zeige INADL Antikörper), a close relative of MUPP1 (zeige MPDZ Antikörper).

Angiomotin Like 2 (AMOTL2) Antigen-Profil

Protein Überblick

Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motins protein family.

Genbezeichner und Symbole assoziert mit AMOTL2

  • angiomotin like 1 (AMOTL1) Antikörper
  • angiomotin like 2a (amotl2a) Antikörper
  • angiomotin like 1 (amotl1) Antikörper
  • angiomotin like 1 (LOC100348712) Antikörper
  • angiomotin like 2 (AMOTL2) Antikörper
  • angiomotin like 2 (amotl2) Antikörper
  • angiomotin like 2 (Amotl2) Antikörper
  • angiomotin-like 2 (Amotl2) Antikörper
  • amotl2 Antikörper
  • AW549739 Antikörper
  • C79691 Antikörper
  • cb308 Antikörper
  • DKFZp468L222 Antikörper
  • jeap Antikörper
  • Lccp Antikörper
  • MASCOT Antikörper
  • mKIAA0989 Antikörper
  • sb:cb308 Antikörper
  • wu:fc41b07 Antikörper
  • wu:fc64c06 Antikörper

Bezeichner auf Proteinebene für AMOTL2

angiomotin like 1 , angiomotin-like protein 1 , angiomotin like 2 , angiomotin-like 2a , angiomotin-like protein 1-like , angiomotin-like protein 2-like , Leman coiled-coil protein , angiomotin-like protein 2

GENE ID SPEZIES
428091 Gallus gallus
451491 Pan troglodytes
558920 Danio rerio
100145436 Xenopus (Silurana) tropicalis
100158429 Xenopus laevis
100172648 Pongo abelii
100348712 Oryctolagus cuniculus
100475663 Ailuropoda melanoleuca
718868 Macaca mulatta
100379727 Xenopus (Silurana) tropicalis
100523696 Sus scrofa
460712 Pan troglodytes
100540953 Meleagris gallopavo
51421 Homo sapiens
65157 Rattus norvegicus
56332 Mus musculus
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