anti-Amyloid beta (Abeta) Antikörper

Abeta encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Zusätzlich bieten wir Ihnen beta Amyloid Kits (12) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Abeta 351 P05067
Abeta 54226 P08592
Abeta 11820 P12023
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Top anti-beta Amyloid Antikörper auf antikoerper-online.de

Showing 10 out of 277 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB 25 μL Anmelden zum Anzeigen 1 bis 2 Tage
$139.00
Details
Human Maus Unkonjugiert IHC, ELISA Abeta oligomer-specific antibody was adsorbed to Nunc-Immuno MaxiSorp plates (Nunc, Roskilde, Denmark) at 2 ug/ml in PBS. 1 ml of a 10 uM Aβ(1-42) sample containing a small fraction of Aβ-oligomers was separated using a superdex G75 (10/30) column. Aβ-fractions collected from the SEC were allowed to bind to OMAB plates for 20 minutes at 0°C. All fractions were analyzed and bound Aβ was detected using a polyclonal rabbit anti-Aβ antibody (ABIN249343) at a 1:1000 dilution followed by an anti-rabbit HRP-conjugated secondary antibody at a 1:5000 dilution (GE healthcare). ECBlue (Medicago, Uppsala, Sweden) was used as a substrate for HRP and the signal was detected by measuring the absorbance at 450 nm. Blocking solution and antibody-dilutions were made with 5% Non-fat dry milk in PBST and all washes were performed with PBS containing 0.1% Tween-20 (PBST). 10 µm of coronal sections from fresh-frozen transgenic mouse brain mutant (A) and wild type (B). Post-fixation in 4% formaldehyde solution, 5 min. OMAB antibody diluted 1:500, incubation at 4ºC ON. Mouse on mouse HRP-Polymer kit according to company instructions. Biocare Medical: BC-MM510 (Histolab) DAB substrate kit for peroxidase. Vector Laboratories: SK-4100 (ImmunKemi) Counterstained with Mayers HTX. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$766.59
Details
Huhn Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of Beta Amyloid (pT743) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Beta Amyloid (pT743) expression in MCF7 colchicine-treated (A), mouse liver (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$575.00
Details
Human Maus Unkonjugiert ELISA, ICC, IF, IHC, IHC (ff), IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - Immunofluorescent detection of beta Amyloid with MOAB-2 in the subiculim of 1-, 2- and 4- month old 5xFAD mice. Scale bar 20 um (from PMID: 22423893). Immunohistochemistry: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - IHC analysis of beta Amyloid on normal mouse brain (left) and 5xFAD mouse brain (right) using DAB with hematoxylin counterstain. The MOAB-2 antibody was used at 1:20 on normal mouse brain and at 1:400 on 5xFAD mouse brain. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Immunohistochemistry: beta Amyloid Antibody [NBP2-25093] - Analysis of APP in human brain tissue with APP antibody at 2.5 ug/ml. Immunohistochemistry-Paraffin: beta Amyloid Antibody [NBP2-25093] - Human brain (Alzheimer's disease) tissue with APP antibody at 10 ug/mL. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Maus Ziege Unkonjugiert ELISA, WB Western Blot: beta Amyloid Antibody [NBP1-97755] - (0.03ug/ml) Analysis of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Rind (Kuh) Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, Act (ligand), WB Western Blot: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Lane 1-10: beta Amyloid pyro E3 peptide. Load: 1 ug per lane 1-2, 0.2 ug per lane 3-4, 0.05 ug per lane 5-6, 0.01 ug per lane 7-8, 0.005 ug per lane 9-10. Primary antibody: Beta Amyloid pyro E3 antibody at 0.5 ug/mL for overnight at 4C. Secondary antibody: IRDye800 rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4C. Predicted/Observed size: 86.9 kDa for beta Amyloid pyro E3 peptide. Cross reactivity with Beta Amyloid 3 peptide is >1000 fold below pyrE3 reactivity and contains no reactivity towards the Beta Amyloid 42 A beta peptide (data not shown). Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE3Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44048 antibody. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$585.06
Details
Fruchtfliege Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, Act (ligand), WB Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - beta-amyloid (pyroglu11) NBP1-44070 in red (left) co-labeled with 6E10 in green (middle) and merge (right). Image from verified customer review. Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE11Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44070 antibody. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$585.06
Details
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details

Abeta Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-beta Amyloid Antikörper

  1. Human Monoclonal beta Amyloid Primary Antibody für ELISA, ICC - ABIN4284085 : Youmans, Tai, Kanekiyo, Stine, Michon, Nwabuisi-Heath, Manelli, Fu, Riordan, Eimer, Binder, Bu, Yu, Hartley, LaDu: Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. in Molecular neurodegeneration 2012 (PubMed)
    Show all 8 Pubmed References

  2. Cow (Bovine) Polyclonal beta Amyloid Primary Antibody für ELISA, ICC - ABIN4284076 : He, Barrow: The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta. in Biochemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal beta Amyloid Primary Antibody für ELISA, IF - ABIN5508784 : Markoutsa, Papadia, Clemente, Flores, Antimisiaris: Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012 (PubMed)
    Show all 4 Pubmed References

  4. Human beta Amyloid Primary Antibody für ELISA (Capture), IF - ABIN1110165 : Levites, Jansen, Smithson, Dakin, Holloway, Das, Golde et al.: Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor ... in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 3 Pubmed References

  5. Fruit Fly (Drosophila melanogaster) Polyclonal beta Amyloid Primary Antibody für ELISA, ICC - ABIN4284077 : Youssef, Florent-Béchard, Malaplate-Armand, Koziel, Bihain, Olivier, Leininger-Muller, Kriem, Oster, Pillot: N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis. in Neurobiology of aging 2008 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal beta Amyloid Primary Antibody für ELISA (Capture), IF - ABIN190335 : Levites, Das, Price, Rochette, Kostura, McGowan, Murphy, Golde: Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. in The Journal of clinical investigation 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human beta Amyloid Primary Antibody für IF, IP - ABIN1110164 : Levites, Smithson, Price, Dakin, Yuan, Sierks, Kim, McGowan, Reed, Rosenberry, Das, Golde: Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal beta Amyloid Primary Antibody für IHC (fro), IHC (p) - ABIN2477631 : Romaguera, Grimalt, Vilaplana: Eczematous and purpuric allergic contact dermatitis from boots. in Contact dermatitis 1990 (PubMed)
    Show all 3 Pubmed References

  9. All Species Monoclonal beta Amyloid Primary Antibody für ELISA, WB - ABIN316413 : Irwin, Edward Wong, Kwon: Determining binding sites of polycyclic aromatic small molecule-based amyloid-beta peptide aggregation modulators using sequence-specific antibodies. in Analytical biochemistry 2014 (PubMed)

Weitere Antikörper gegen beta Amyloid Interaktionspartner

Human Amyloid beta (Abeta) Interaktionspartner

  1. Data suggest that aggregates of amyloid beta(1-40) induce excessive generation of reactive oxygen species, MAPK (zeige MAPK1 Antikörper)/NFkappaB (zeige NFKB1 Antikörper) signaling activation, and NLRP3 (zeige NLRP3 Antikörper) inflammasome activation in retinal pigment epithelial cells mimicking changes seen in age-related macular degeneration; this mechanism is dependent on NADPH oxidase (zeige NOX1 Antikörper).

  2. These results demonstrate a stage-dependent plasma Abeta (zeige APP Antikörper) increase that is augmented by loss of glomerulotubular integrity, low body weight, and inflammation, demonstrating a multifaceted role of renal dysfunction in Abeta (zeige APP Antikörper) retention.

  3. Combining a murine APP (zeige APP Antikörper)-deficient and a human APP (zeige APP Antikörper)-transgenic strain, we were able to analyse the progression of the cortical amyloidosis independent of the murine variant. The lack of endogenous mAPP (zeige XPNPEP2 Antikörper) resulted in accelerated deposition and, thus, increased number of senile plaques and higher levels of aggregated hAbeta.

  4. APP levels then decrease progressively as a function of age in close relationship with the gradual normalization of FMRP and hnRNP C levels.

  5. In Alzheimer's Disease brain, amyloid Beta-protein binds to synapses and requires the expression of amyloid precursor protein (zeige APP Antikörper) to disrupt synaptic activity.

  6. activation of mTOR (zeige FRAP1 Antikörper) signalling via RHEB (zeige RHEB Antikörper) over-expression inhibited the starvation-induced autophagy but did not affect trafficking of tf-Amyloid precursor protein (APP (zeige APP Antikörper)). These results show tf-APP (zeige APP Antikörper) can be used to determine how APP (zeige APP Antikörper) is trafficked through the lysosomal system of the cell.

  7. Study found that FERMT2 (zeige FERMT2 Antikörper) (a beta3-integrin (zeige ITGB3 Antikörper) co-activator) was significantly associated with a variation in cerebrospinal fluid Abeta (zeige APP Antikörper) peptide levels in 2886 Alzheimer's disease cases.Under-expression of FERMT2 (zeige FERMT2 Antikörper) increases Abeta (zeige APP Antikörper) peptide production by raising levels of mature APP (zeige APP Antikörper) at the cell surface and facilitating its recycling

  8. a 99-aa C-terminal fragment of APP (zeige APP Antikörper),C99, in addition to its localization in endosomes, can also be found in mitochondria-associated endoplasmic reticulum (ER) membranes, where it is normally processed rapidly by gamma-secretase.

  9. Photoinduced electrons of g-C3 N4 generate reactive oxygen resulting in photooxidation of amyloid peptides that blocks Abeta (zeige APP Antikörper) aggregation.

  10. Studies indicate that amyloid precursor-like protein 2 (APLP2 (zeige APLP2 Antikörper)) and amyloid precursor protein (APP (zeige APP Antikörper)) are linked to increased tumor cell proliferation, migration, and invasion.

Mouse (Murine) Amyloid beta (Abeta) Interaktionspartner

  1. This study demonstrates the neuroprotective effect of TSG (zeige TWSG1 Antikörper) on APP (zeige APP Antikörper) expression, suggesting that TSG (zeige TWSG1 Antikörper) may be beneficial for AD prevention and treatment.

  2. SNX15 (zeige SNX15 Antikörper) regulates the recycling of APP (zeige APP Antikörper) to cell surface and, thus, its processing for Abeta (zeige APP Antikörper) generation.

  3. Immunohistochemical analysis confirmed increased amount of NOS1 (zeige NOS1 Antikörper) protein in neuronal somata and processes in the perilesional cortex in APP (zeige APP Antikörper)/PS1 (zeige PSEN1 Antikörper)-severe traumatic brain injury(TBI) mice compared to APP (zeige APP Antikörper)/PS1 (zeige PSEN1 Antikörper)-sham (p < 0.05) or Wt-sTBI mice (p < 0.01).

  4. Combining a murine APP (zeige APP Antikörper)-deficient and a human APP (zeige APP Antikörper)-transgenic strain, we were able to analyse the progression of the cortical amyloidosis independent of the murine variant. The lack of endogenous mAPP (zeige XPNPEP2 Antikörper) resulted in accelerated deposition and, thus, increased number of senile plaques and higher levels of aggregated hAbeta.

  5. our findings indicate that sortilin (zeige SORT1 Antikörper) is a beneficial protein for the reduction of amyloid pathology in APP (zeige APP Antikörper)/PS1 (zeige PSEN1 Antikörper) mice by promoting APP (zeige APP Antikörper) degradation

  6. APP levels then decrease progressively as a function of age in close relationship with the gradual normalization of FMRP and hnRNP C levels.

  7. a 99-aa C-terminal fragment of APP (zeige APP Antikörper),C99, in addition to its localization in endosomes, can also be found in mitochondria-associated endoplasmic reticulum (ER) membranes, where it is normally processed rapidly by gamma-secretase.

  8. The authors concluded that the FcgammaRIIb-SHIP2 (zeige INPPL1 Antikörper) axis links Abeta (zeige APP Antikörper) neurotoxicity to tau pathology by dysregulating phosphoinositide metabolism, providing insight into therapeutic potential against Alzheimer's disease.

  9. results suggest that PrP(C (zeige PRNP Antikörper)) recognizes structural features common to both Abeta (zeige APP Antikörper) oligomers and fibril ends and that this interaction could contribute to the neurotoxic effect of Abeta (zeige APP Antikörper) aggregates.

  10. Our study provides the first direct evidence that Abeta, an AD-linked factor, is associated to the pathogenesis of ALS and provides molecular clues to understand common aggregation mechanisms in the pathogenesis of neurodegenerative diseases.

beta Amyloid (Abeta) Antigen-Profil

Protein Überblick

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Amyloid beta (Abeta) Antikörper

  • amyloid beta precursor protein (APP) Antikörper
  • amyloid beta precursor protein (app) Antikörper
  • amyloid beta precursor protein (App) Antikörper
  • amyloid beta (A4) precursor protein (App) Antikörper
  • aaa Antikörper
  • Abeta Antikörper
  • Abpp Antikörper
  • ad1 Antikörper
  • Adap Antikörper
  • Ag Antikörper
  • appi Antikörper
  • betaApp Antikörper
  • ctfgamma Antikörper
  • Cvap Antikörper
  • E030013M08Rik Antikörper
  • PN-II Antikörper
  • pn2 Antikörper

Bezeichner auf Proteinebene für anti-Amyloid beta (Abeta) Antikörper

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II , amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease) , amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) , beta-amyloid precursor protein , alzheimer disease amyloid A4 protein homolog , amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) , ABPP , AG , amyloid A4 , amyloidogenic glycoprotein , appican , protease nexin II

GENE ID SPEZIES
351 Homo sapiens
448208 Xenopus (Silurana) tropicalis
100427716 Macaca mulatta
54226 Rattus norvegicus
11820 Mus musculus
Ausgewählte Anbieter für anti-beta Amyloid (Abeta) Antikörper
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