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anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) Antikörper

The protein encoded by APBA1 is a member of the X11 protein family. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
APBA1 319924 B2RUJ5
APBA1 83589 O35430
APBA1 320 Q02410
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Top anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 Antikörper auf antikoerper-online.de

Showing 10 out of 78 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB ABIN190802 (0.1µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Kaninchen Unkonjugiert EIA, IF, WB Western blot analysis of APBA1 in rat brain tissue lysate with APBA1 Antibody  at 0.5 µg/ml in (A) the absence and (B) the presence of blocking peptide. 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
357,50 €
Details
Human Ziege Unkonjugiert WB 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
357,50 €
Details
Maus Maus Unkonjugiert IF, IHC, WB Western blot analysis of Mint1 on a rat cerebrum lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-Mint1 antibody. Immunofluorescence staining of rat neurons. 50 μg Anmelden zum Anzeigen 2 bis 4 Tage
146,73 €
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: APBA1 Antibody [NBP1-06015] - (0.1ug/ml) staining of Human Brain (Cerebellum) 35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of UROP11 in mouse spleen tissue lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-APBA1 Antibody Titration: 0.2-1 ug/mlPositive Control: Raji cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
705,40 €
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, WB dilution: 1 : 1000, sample: rat hippocampus homogenate Indirect immunostaining of rat hippocampus neurons with anti-Mint 1 (dilution 1 : 200; red) and anti-synapsin (cat. no. 106 001; dilution 1 : 500, green). 50 μg Anmelden zum Anzeigen 1 bis 2 Tage
341,00 €
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
505,48 €
Details

APBA1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 Antikörper

  1. Mouse (Murine) Monoclonal APBA1 Primary Antibody für IF, IHC - ABIN968327 : Biederer, Südhof: Mints as adaptors. Direct binding to neurexins and recruitment of munc18. in The Journal of biological chemistry 2001 (PubMed)
    Zeige alle 4 Referenzen für ABIN968327

  2. Human Polyclonal APBA1 Primary Antibody für EIA, IF - ABIN1450013 : Borg, Ooi, Levy, Margolis: The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein. in Molecular and cellular biology 1996 (PubMed)
    Zeige alle 4 Referenzen für ABIN1450013

  3. Human Polyclonal APBA1 Primary Antibody für EIA, WB - ABIN501114 : Verlaeten, Casery, Cavagna, Naville, Giraudon, Belin, Begeot, Bernard: Identification of Urop11, a novel leptin-modulated gene that is upregulated in the hypothalamus of mice with virus-induced obesity. in Journal of molecular endocrinology 2007 (PubMed)

  4. Rat (Rattus) Polyclonal APBA1 Primary Antibody für ICC, IHC - ABIN1742315 : Boyken, Grønborg, Riedel, Urlaub, Jahn, Chua: Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. in Neuron 2013 (PubMed)

  5. Human Polyclonal APBA1 Primary Antibody für ELISA, WB - ABIN451592 : Jacobs, Williams, Francis: Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11alpha protein up-regulation in Alzheimer's disease. in Neuroscience 2006 (PubMed)

Weitere Antikörper gegen Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 Interaktionspartner

Mouse (Murine) Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) Interaktionspartner

  1. Due to the multiple interacting partners of X11alpha, dysfunction or alteration in X11alpha will have a significant cellular effect.

  2. Mint1 826 bridges APP (zeige APP Antikörper) to the small GTPase (zeige RACGAP1 Antikörper)

  3. Expression of Apba1 in the mouse hippocampus is modulated by a sequence variant (B2 SINE indel) in the 3' UTR (zeige UTS2R Antikörper) of Comt (catechol-O-methyltransferase (zeige COMT Antikörper)).

  4. Our data support a function for both GSK3 (zeige GSK3b Antikörper) and CDK5 (zeige CDK5 Antikörper) in amyloid precursor protein (zeige APP Antikörper) processing, further implicating these two kinases in the pathogenesis of Alzheimer's disease.

  5. Can be considered a key molecule in the hypothalamic integration pathway, important as a target of leptin (zeige LEP Antikörper) action.

  6. Reports have demonstrated that KIF17 (zeige KIF17 Antikörper)-Mint1 association was disrupted and transported cargo was released from its microtubule-based transport when Ser (zeige SIGLEC1 Antikörper) 1029 of KIF17 (zeige KIF17 Antikörper) was phosphorylated.

  7. X11s associate primarily with APP (zeige APP Antikörper) molecules that are outside of DRM (zeige GREM1 Antikörper), that the dissociation of APP (zeige APP Antikörper)-X11/X11L (zeige APBA2 Antikörper) complexes leads to entry of APP (zeige APP Antikörper) into DRM (zeige GREM1 Antikörper), and that cleavage of uncomplexed APP (zeige APP Antikörper) by BACE (zeige BACE Antikörper) within DRM (zeige GREM1 Antikörper)

  8. These results suggest that the three Mint/X11 proteins regulate Abeta (zeige APP Antikörper) production by a novel mechanism that may have implications for therapeutic approaches to altering APP (zeige APP Antikörper) cleavage in Alzheimer's disease.

Human Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) Interaktionspartner

  1. Mint1 causes amyloid precursor protein (zeige APP Antikörper) accumulation in the trans-Golgi network.

  2. Mints are necessary for activity-induced APP (zeige APP Antikörper) and PS1 (zeige PSEN1 Antikörper) trafficking and provide insight into the cellular fate of APP (zeige APP Antikörper) in endocytic pathways essential for Abeta (zeige APP Antikörper) production.

  3. Mint1 826 bridges APP (zeige APP Antikörper) to the small GTPase (zeige RACGAP1 Antikörper)

  4. an autoinhibitory mechanism in Mint1 is important for regulating APP (zeige APP Antikörper) processing and may provide novel therapies for Alzheimer's disease

  5. Transcriptional co-activators Taz (zeige TAZ Antikörper) and Yap (zeige YAP1 Antikörper) mediate signaling via the amyloid beta protein precursor paralogues APLP1 (zeige APLP1 Antikörper) and APLP2 (zeige APLP2 Antikörper) through interactions with Mint1 and Mint3 (zeige APBA3 Antikörper).

  6. Study identified the conserved binding site for the peptide on the CASK (zeige CASK Antikörper) calmodulin (zeige CALM1 Antikörper) kinase domain. A related EPIWVMRQ peptide from Mint1 was also discovered to be sufficient for binding.

  7. Our findings show a new function for X11alpha that may impact on Alzheimer's disease pathogenesis.

  8. Methylation of MINT1 was significantly more prevalent in UC-CRC (zeige CALR Antikörper) cases compared with controls.

  9. ApoEr2 (zeige LRP8 Antikörper) regulates cell movement, and both X11alpha and Reelin (zeige RELN Antikörper) enhance this effect.

  10. A novel consensus sequence for interaction with the PDZ (zeige INADL Antikörper)-1 and PDZ (zeige INADL Antikörper)-2 domains of amyloid precursor protein (APP (zeige APP Antikörper))-interacting proteins Mint1, Mint2 (zeige APBA2 Antikörper), and Mint3 (zeige APBA3 Antikörper) is reported, with multiple novel interactors for these proteins.

Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.

Genbezeichner und Symbole assoziert mit APBA1

  • amyloid beta (A4) precursor protein-binding, family A, member 1 (APBA1) Antikörper
  • amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) (apba1) Antikörper
  • ketopantoate reductase (apbA1) Antikörper
  • 2-dehydropantoate 2-reductase (apbA1) Antikörper
  • 2-dehydropantoate 2-reductase (apba1) Antikörper
  • amyloid beta (A4) precursor protein-binding, family A, member 1 (apba1) Antikörper
  • amyloid beta (A4) precursor protein binding, family A, member 1 (Apba1) Antikörper
  • amyloid beta (A4) precursor protein-binding, family A, member 1 (Apba1) Antikörper
  • 6430513E09Rik Antikörper
  • APBA1 Antikörper
  • D9S411E Antikörper
  • Lin-10 Antikörper
  • LIN10 Antikörper
  • Mint Antikörper
  • MINT1 Antikörper
  • Urop11 Antikörper
  • X11 Antikörper
  • X11A Antikörper
  • X11ALPHA Antikörper

Bezeichner auf Proteinebene für APBA1

amyloid beta (A4) precursor protein-binding, family A, member 1 , amyloid beta A4 precursor protein-binding, family A, member 1 , amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) , ketopantoate reductase , 2-dehydropantoate 2-reductase , Amyloid beta A4 precursor protein-binding family A member 1 , amyloid beta A4 precursor protein-binding family A member 1-like , UROP11-110 , adapter protein X11alpha , amyloid beta A4 precursor protein-binding family A member 1 , mint-1 , neuron-specific X11 protein , neuronal Munc18-1-interacting protein 1 , amyloid beta (A4) precursor protein-binding family A APBA1: amyloid beta (A4) precursor protein-binding family A member 1 (X11) , amyloid beta (A4) precursor protein-binding, family A, APBA1: amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) , adaptor protein X11alpha , neuronal munc18-1-interacting protein 1 , phosphotyrosine-binding/-interacting domain (PTB)-bearing protein

GENE ID SPEZIES
472947 Pan troglodytes
565507 Danio rerio
699838 Macaca mulatta
4247161 Ralstonia eutropha H16
4606254 Azoarcus sp. BH72
9788884 Pantoea vagans C9-1
100380423 Salmo salar
100390315 Callithrix jacchus
100439123 Pongo abelii
100483732 Ailuropoda melanoleuca
100485825 Xenopus (Silurana) tropicalis
319924 Mus musculus
83589 Rattus norvegicus
320 Homo sapiens
427246 Gallus gallus
100686233 Canis lupus familiaris
100513711 Sus scrofa
515571 Bos taurus
Ausgewählte Anbieter für anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) Antikörper
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