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The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. Zusätzlich bieten wir Ihnen AIMP2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal AIMP2 Primary Antibody für IHC (p), WB - ABIN3044411
Zheng, Liu, Liu, Ma, Zhou, Chen, Chang, Wang, Yang, He: Cucurbitacin B inhibits growth and induces apoptosis through the JAK2/STAT3 and MAPK pathways in SH?SY5Y human neuroblastoma cells. in Molecular medicine reports 2014
Show all 3 Pubmed References
AIMP2 underexpression is associated with lung neoplasms.
These data indicate monomer-dimer equilibrium of AIMP2-DX2 in solution. These results form the basis for the structure-function study of oncogenic AIMP2-DX2.
analysis of the heterotetrameric complex structure of the glutathione transferase (GST (zeige SLCO6A1 Antikörper)) domains shared among the four MSC (zeige MSC Antikörper) components, methionyl-tRNA synthetase (zeige MARS Antikörper) (MRS), glutaminyl-prolyl-tRNA synthetase (EPRS (zeige EPRS Antikörper)), AIMP2 and AIMP3 (zeige EEF1E1 Antikörper)
Ubiquitin and SUMO compete for the same lysine (K242) on influenza A virus M1 and the interaction of viral NS2 with human AIMP2 facilitates the switch of the M1 modification from ubiquitination to SUMOylation, thus increasing viral replication.
These findings suggested that, although excessive accumulation of oxidative DNA damage was present in LSCs, the relatively decreased phosphorylation of p38 (zeige CRK Antikörper) might help leukemic cells escape senescence and apoptosis.
Transgeneic overexpression of AIMP2 led to a selective, age-dependent, progressive loss of dopaminergic neurons.
The tumorigenic activity of AIMP2-DX2 can be controlled by the small chemical BC-DXI01, which can selectively suppress the AIMP2-DX2 mRNA transcript.
AIMP2-DX2, a splicing variant of tumor suppressor AIMP2, can be a therapeutic target to control chemoresistant epithelial ovarian cancer .
downregulation of AIMP2 lacking exon 2 (AIMP2-DX2), expressed in different cancer cells, suppressed the epidermal growth factor receptor (zeige EGFR Antikörper)/mitogen activated protein kinase (zeige MAPK1 Antikörper) signaling pathway
ribozyme could selectively deliver the activity of a suicide gene into the AIMP2-DX2 RNA expressing lung cancer cells and thereby specifically and effectively retard the growth of the cancer cells with prodrug treatment.
functional significance of AIMP2 in determination of cell proliferation and death, and as a haploinsufficient tumor suppressor.
The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are arranged in a tail-to-tail fashion. JTV1 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. JTV1 is transcribed in the opposite direction compared to HRI and PMS2. The function of the JTV1 gene product is unknown.
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
, aminoacyl tRNA synthase complex-interacting multifunctional protein 2
, ARS-interacting multi-functional protein 2
, multisynthase complex auxiliary component p38
, multisynthetase complex auxiliary component p38
, protein JTV-1
, ARS interacting multifunctional protein 2