anti-Adenosylhomocysteinase (AHCY) Antikörper

S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. Zusätzlich bieten wir Ihnen AHCY Proteine (95) und AHCY Kits (21) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
AHCY 191 P23526
AHCY 29443 P10760
AHCY 269378 P50247
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Top anti-AHCY Antikörper auf antikoerper-online.de

Showing 10 out of 110 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-AHCY Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Human Liver 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Ahcy Antibody Titration: 1.0 ug/ml Positive Control: Mouse Pancreas 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Maus Kaninchen Unkonjugiert FACS, IHC (p), WB AHCY Antibody (N-term) (ABIN655151) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB AHCY Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. AHCY Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AHCY Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with RABBIT ANTI-SAHH POLYCLONAL ANTIBODY, Unconjugated (ABIN708611) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details
Hamster Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Maus Unkonjugiert ELISA, WB AHCY monoclonal antibody (M07A), clone 4H2 Western Blot analysis of AHCY expression in A-549 . Western Blot detection against Immunogen (73.26 KDa) . 200 μL Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Maus Unkonjugiert WB AHCY Antibody  western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the AHCY antibody detected the AHCY protein (arrow). 0.1 mL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details

AHCY Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-AHCY Antikörper

  1. Human Monoclonal AHCY Primary Antibody für ELISA, WB - ABIN513196 : Fernandez-Sanchez, Gonatopoulos-Pournatzis, Preston, Lawlor, Cowling: S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation. in Molecular and cellular biology 2009 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal AHCY Primary Antibody für IF (p), IHC (p) - ABIN708611 : Huang, Huan, Liu: A comparative proteomic analysis reveals important proteins for the fertilization and early embryonic development of the oyster Crassostrea gigas. in Proteomics 2016 (PubMed)

  3. Human Monoclonal AHCY Primary Antibody für ELISA, WB - ABIN559816 : Kim, Kang, Lee, Lee, Yu, Kim, Lee: Identification of S100A8 and S100A9 as serological markers for colorectal cancer. in Journal of proteome research 2009 (PubMed)

  4. Human Polyclonal AHCY Primary Antibody für IHC - ABIN965520 : Yuan, Borchardt: Photoaffinity labeling of human placental S-adenosylhomocysteine hydrolase with [2-3H]8-azido-adenosine. in The Journal of biological chemistry 1995 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen AHCY Interaktionspartner

Human Adenosylhomocysteinase (AHCY) Interaktionspartner

  1. In order to enable the development of small molecule AHCY inhibitors as targeted cancer therapeutics we developed an assay based on a RapidFire high-throughput mass spectrometry detection system, which allows the direct measurement of AHCY enzymatic activity.

  2. SAH (zeige ACSM3 Antikörper) hydrolase deficiency can remain asymptomatic in childhood, and the disorder can be associated with early onset hepatocellular carcinoma.

  3. H19 (zeige NCKAP1 Antikörper) knockdown activates SAHH, leading to increased DNMT3B (zeige DNMT3B Antikörper)-mediated methylation of an lncRNA-encoding gene Nctc1 within the Igf2-H19 (zeige NCKAP1 Antikörper)-Nctc1 locus.

  4. S-adenosylhomocysteine hydrolase is regulated by lysine acetylation

  5. SAHH can promote apoptosis, inhibit migration and adhesion of ESCC cells suggesting that it may be involved in carcinogenesis of the esophagus.

  6. A fluorescence-based assay for the measurement of S-adenosylhomocysteine hydrolase activity in biological samples.

  7. Maintenance of ionizable active-site residues in catalytically suitable protonation states in closed forms of placental AHCY may be assisted by a water chain, stabilized by Asp182, that can import and export protons from and to the environment.

  8. SAHH, which is diffuse in the cytoplasm of nonmotile Dictyostelium amoebae and human neutrophils, concentrates with F-actin in pseudopods at the front of motile, chemotaxing cells

  9. In the case of Hs-SAHH, the slow-binding phase terminates in micromolar affinity, but over a period of hours, the dissociation rate constant decreases until the final equilibrium affinity is in the nanomolar range.

  10. We found clinically relevant levels of Hcy (0-500 microM) induced elevation of SAH (zeige ACSM3 Antikörper), declination of SAM (zeige TTN Antikörper) and SAM (zeige TTN Antikörper)/SAH (zeige ACSM3 Antikörper) ratio and reduced expression of SAHH and MBD2 (zeige DPEP2 Antikörper), but increased activity of DNMT3a (zeige DNMT3A Antikörper) and DNMT3b (zeige DNMT3B Antikörper) affecting DNA methylation (zeige HELLS Antikörper)

Mouse (Murine) Adenosylhomocysteinase (AHCY) Interaktionspartner

  1. H19 (zeige NCKAP1 Antikörper) knockdown activates SAHH, leading to increased DNMT3B (zeige DNMT3B Antikörper)-mediated methylation of an lncRNA-encoding gene Nctc1 within the Igf2-H19 (zeige NCKAP1 Antikörper)-Nctc1 locus.

  2. Ahcy was identified from coupling of methylation with gene expression data, shed light on the underlying mechanisms of cytosine demethylation under methyl-deficient conditions.

  3. report the crystallization of mouse SAHH in the presence of the reaction product adenosine. The crystals diffracted to at least 1.55 A degrees resolution and are suitable for X-ray structure analysis at high resolution.

  4. report that Myc (zeige MYC Antikörper) promotes upregulation of S-adenosyl homocysteine hydrolase.

Zebrafish Adenosylhomocysteinase (AHCY) Interaktionspartner

  1. AHCYL1 (zeige AHCYL1 Antikörper) has a different function from AHCY and plays an important role in embryogenesis by modulating inositol 1,4,5-trisphosphate receptor function for the intracellular calcium release

  2. Hepatic steatosis and liver degeneration are prominent features of the ducttrip (dtp) mutant phenotype. Positional cloning identified a causative mutation in the gene encoding S-adenosylhomocysteine hydrolase (Ahcy).

AHCY Antigen-Profil

Protein Überblick

S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit AHCY

  • adenosylhomocysteinase (AHCY) Antikörper
  • adenosylhomocysteinase (ahcy) Antikörper
  • adenosylhomocysteinase (ahcY) Antikörper
  • Adenosylhomocysteinase (ahcY) Antikörper
  • adenosylhomocysteinase (Mmah_0523) Antikörper
  • adenosylhomocysteinase (Srot_2217) Antikörper
  • adenosylhomocysteinase (Ndas_3755) Antikörper
  • adenosylhomocysteinase (Deba_0936) Antikörper
  • adenosylhomocysteinase (Palpr_2392) Antikörper
  • adenosylhomocysteinase (Calni_0569) Antikörper
  • adenosylhomocysteinase (LOC100282150) Antikörper
  • adenosylhomocysteinase (Intca_2510) Antikörper
  • adenosylhomocysteinase (Marky_0392) Antikörper
  • adenosylhomocysteinase (Desac_1394) Antikörper
  • S-adenosylhomocysteine hydrolase (Tc00.1047053511229.50) Antikörper
  • S-adenosylhomocysteine hydrolase (Tc00.1047053511589.200) Antikörper
  • S-adenosylhomocysteine hydrolase (Tb11.01.1350) Antikörper
  • S-adenosylhomocysteine hydrolase (LmjF36.3910) Antikörper
  • S-adenosylhomocysteine hydrolase (MCYG_06244) Antikörper
  • S-adenosylhomocysteine hydrolase (Ahcy) Antikörper
  • adenosylhomocysteinase (Ahcy) Antikörper
  • adenosylhomocysteinase (ahcy-b) Antikörper
  • S-adenosylhomocysteine hydrolase (ahcy) Antikörper
  • AA987153 Antikörper
  • adoHcyase Antikörper
  • ahcy Antikörper
  • AL024110 Antikörper
  • cb1079 Antikörper
  • CuBP Antikörper
  • D150 Antikörper
  • hm:zeh1173 Antikörper
  • hm:zeh1364 Antikörper
  • PSPTO5068 Antikörper
  • SAHH Antikörper
  • wu:fj67b02 Antikörper

Bezeichner auf Proteinebene für AHCY

S-adenosylhomocysteine hydrolase , adenosylhomocysteinase , Adenosylhomocysteinase , adenosylhomocysteinase-like , S-adenosyl-L-homocysteine hydrolase , adoHcyase , S-adenosyl-L-homocysteine hydrolase B , adenosylhomocysteinase B , adoHcyase B , liver copper-binding protein , dtp

GENE ID SPEZIES
458190 Pan troglodytes
733486 Xenopus (Silurana) tropicalis
1186753 Pseudomonas syringae pv. tomato str. DC3000
8681312 Methanocella paludicola SANAE
8790426 Azospirillum sp. B510
8994525 Salinibacter ruber M8
9483094 Candidatus Nitrospira defluvii
100440671 Pongo abelii
8982664 Methanohalophilus mahii DSM 5219
9180283 Segniliparus rotundus DSM 44985
9247624 Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111
9493389 Desulfarculus baarsii DSM 2075
10000059 Paludibacter propionicigenes WB4
10008577 Calditerrivibrio nitroreducens DSM 19672
100282150 Zea mays
10085337 Intrasporangium calvum DSM 43043
10433277 Marinithermus hydrothermalis DSM 14884
10436597 Desulfobacca acetoxidans DSM 11109
3539733 Trypanosoma cruzi strain CL Brener
3547847 Trypanosoma cruzi strain CL Brener
3664299 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5655685 Leishmania major strain Friedlin
9227886 Arthroderma otae CBS 113480
100113808 Nasonia vitripennis
191 Homo sapiens
29443 Rattus norvegicus
503682 Xenopus laevis
477198 Canis lupus familiaris
497050 Sus scrofa
508158 Bos taurus
269378 Mus musculus
387530 Danio rerio
Ausgewählte Anbieter für anti-AHCY (AHCY) Antikörper
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