Adenosine Deaminase, RNA-Specific, B1 (ADARB1) ELISA Kits

ADARB1 encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Zusätzlich bieten wir Ihnen RED1 Antikörper (35) und RED1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
ADARB1 104 P78563
ADARB1 110532 Q91ZS8
ADARB1 25367 P51400
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Weitere ELISA Kits für RED1 Interaktionspartner

Human Adenosine Deaminase, RNA-Specific, B1 (ADARB1) Interaktionspartner

  1. 2-way interaction between TPH2 (zeige TDO2 ELISA Kits) rs4290270 and general traumas revealed that TT homozygotes with history of general traumas had an increased risk for suicide attempt. 3-way interaction of general traumas, TPH2 (zeige TDO2 ELISA Kits) rs4290270 and ADARB1 rs4819035 indicated that highest predisposition to suicide attempt was observed in individuals who experienced general traumas and were TT homozygote for rs4290270 and TT homozygote for rs4819035.

  2. The range of human disease associated with ADAR1 (zeige ADAR ELISA Kits) mutations may extend further to include other inflammatory conditions while ADAR2 mutations may affect psychiatric conditions.

  3. Four crystal structures of the human ADAR2 deaminase domain bound to RNA duplexes bearing a mimic of the deamination reaction intermediate.

  4. we determined the importance of specific amino acids at 19 different positions in the ADAR2 5' binding loop and revealed six residues that provide essential structural elements supporting the fold of the loop and key RNA-binding functional groups. This work provided new insight into RNA recognition by ADAR2 and established a new tool for defining structure-function relationships in ADAR (zeige ADAR ELISA Kits) reactions.

  5. Data indicate that ADAR2 suppresses tumor growth and induces apoptosis by editing and stabilizing IGFBP7 (zeige IGFBP7 ELISA Kits) in esophageal squamous cell carcinoma.

  6. These findings suggest that adenosine deaminase acting on RNA (zeige ADAR ELISA Kits) 2 is subject to different regulations by DNA methyltransferase (zeige DNMT1 ELISA Kits) and histone deacetylase (zeige HDAC1 ELISA Kits) enzymes in neuronal SH-SY5Y cells.

  7. These data suggest that, like ADAR2, underlying sequences in dsRNA may influence how NF90 (zeige MMP4 ELISA Kits) recognizes its target RNAs

  8. Detailed structural analysis indicates that the minor groove width of dsRNA and global shape of RNA may play an important role in the specific reading mechanism of ADAR2.

  9. A-to-I RNA editing levels catalyzed by ADAR1 (zeige ADAR ELISA Kits) and ADARB1 decreased in Alzheimer's disease patients' brain tissues, mainly in the hippocampus and to a lesser degree in the temporal and frontal lobes.

  10. we conclude that this aberrant alternative splicing pattern of ADAR2 downregulates A-to-I editing in glioma

Mouse (Murine) Adenosine Deaminase, RNA-Specific, B1 (ADARB1) Interaktionspartner

  1. ADARB1 mediates adenosine to inosine RNA editing in the testis, and these editing events are dispensable for male fertility in an inbred mouse strain in the lab.

  2. that ADAR2 is a mediator of injury-induced tactile allodynia and thus a potential therapeutic target for the treatment of neuropathic pain

  3. Results show that ADAR2 is important in site-specific changes of protein coding sequences but has relatively modest effects on gene expression and splicing in the adult mouse frontal cortex.

  4. Thus, Adarb1 and Adarb2 (zeige ADARB2 ELISA Kits) have nearly exclusive expression within brain tissue, while Adar (zeige ADAR ELISA Kits) has more appreciable expression across multiple tissues.

  5. After fear conditioning protocol, mRNA expression of ADAR2 increased in amygdala and hippocampus, and those mice had a learning-dependent increase in the alternatively spliced inactive form of ADAR2 in the amygdala.

  6. ADAR2 is a key factor for maintaining edited-miRNA population and balancing the expression of several essential miRNAs involved in cancer.

  7. This study clearly demonstrates that ADAR2 influences miRNA abundance and targeting at several levels in the mouse brain.

  8. chronically elevated intraocular pressure in adult mice reduces expression of the ADAR2 enzyme.

  9. Analysis of editing in the filamin A (zeige FLNA ELISA Kits) encoding mRNA shows very high editing levels outside the nervous system; further shows FLNA (zeige FLNA ELISA Kits) editing is mainly achieved by ADAR2 but that in some cases ADAR1 (zeige ADAR ELISA Kits) can efficiently compensate for ADAR2.

  10. Results suggest that ADAR2-reduction is associated with progressive deterioration of nuclear architecture, resulting in vacuolated nuclei due to a Ca2 (zeige CA2 ELISA Kits)+-permeable AMPA (zeige GRIA3 ELISA Kits) receptor-mediated mechanism

Zebrafish Adenosine Deaminase, RNA-Specific, B1 (ADARB1) Interaktionspartner

  1. Adar2 Edits the Q/R site of AMPA (zeige GRIA3 ELISA Kits) receptor Subunit gria2alpha transcript to ensure normal development of nervous system and cranial neural crest cells

RED1 (ADARB1) Antigen-Profil

Beschreibung des Gens

This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.

Genbezeichner und Symbole assoziert mit ADARB1

  • adenosine deaminase, RNA specific B1 (ADARB1) Antikörper
  • adenosine deaminase, RNA-specific, B1 (adarb1) Antikörper
  • adenosine deaminase, RNA-specific, B1 L homeolog (adarb1.L) Antikörper
  • adenosine deaminase, RNA-specific, B1 (Adarb1) Antikörper
  • adenosine deaminase, RNA-specific, B1a (adarb1a) Antikörper
  • 1700057H01Rik Antikörper
  • adar2 Antikörper
  • adarb1 Antikörper
  • AW124433 Antikörper
  • AW558573 Antikörper
  • BB220382 Antikörper
  • D10Bwg0447e Antikörper
  • DRABA2 Antikörper
  • DRADA2 Antikörper
  • red1 Antikörper

Bezeichner auf Proteinebene für ADARB1

adenosine deaminase, RNA-specific, B1 (RED1 homolog rat) , adenosine deaminase, RNA-specific, B1 (RED1 homolog) , adenosine deaminase, RNA-specific, B1 , RNA-specific adenosine deaminase B1 , double-stranded RNA-specific editase 1-like , RED1 homolog , RNA editase , RNA editing deaminase 1 , RNA-editing deaminase 1 , RNA-editing enzyme 1 , adenosine deaminase, RNA-specific, B1 (homolog of rat RED1) , double-stranded RNA-specific editase 1 , dsRNA adenosine deaminase DRADA2 , dsRNA adenosine deaminase , RNA editing deaminase of glutamate receptors , double-stranded RNA-specific editase

GENE ID SPEZIES
521761 Bos taurus
100124739 Xenopus (Silurana) tropicalis
100339367 Oryctolagus cuniculus
100483845 Ailuropoda melanoleuca
100589130 Nomascus leucogenys
495438 Xenopus laevis
374087 Gallus gallus
104 Homo sapiens
487809 Canis lupus familiaris
110532 Mus musculus
25367 Rattus norvegicus
58134 Danio rerio
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