anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) Antikörper

ADARB1 encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Zusätzlich bieten wir Ihnen RED1 Proteine (7) und RED1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ADARB1 104 P78563
ADARB1 110532 Q91ZS8
ADARB1 25367 P51400
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Top anti-RED1 Antikörper auf antikoerper-online.de

Showing 10 out of 35 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ADARB1 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HepG2 cells, using ADARB1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Huhn Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of ADAR2 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of ADAR2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), SimWes, WB Immunohistochemistry-Paraffin: RED1 Antibody [NBP1-90240] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules. Simple Western: RED1 Antibody [NBP1-90240] - Electropherogram image(s) of corresponding Simple Western lane view. RED1 antibody was used at 1:20 dilution on RT-4 lysates(s). 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$491.63
Details
Ratte Schaf Unkonjugiert IF, WB Immunofluorescence staining of mouse anterior horns of spinal cord at 6 months, 15 months and 26 months of age. Antibody used at 1/100 dilution and visualized using Donkey anti-Sheep conjugated to Alexa 555 Dye (red color). The blue color is a fluorescent nuclear probe, TOPRO3. (Image modified from original in citation 1) 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert IHC (p), WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details

ADARB1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,
,
,
Mouse (Murine)


Rat (Rattus)
,

Am meisten referenzierte anti-RED1 Antikörper

  1. Rat (Rattus) Polyclonal RED1 Primary Antibody für IF, WB - ABIN264972 : Yamashita, Chai, Teramoto, Tsuji, Shimazaki, Muramatsu, Kwak: Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons. in EMBO molecular medicine 2013 (PubMed)

  2. Cow (Bovine) Polyclonal RED1 Primary Antibody für WB - ABIN2778757 : Kawahara, Ito, Ito, Tsuji, Kwak: Novel splice variants of human ADAR2 mRNA: skipping of the exon encoding the dsRNA-binding domains, and multiple C-terminal splice sites. in Gene 2005 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal RED1 Primary Antibody für IHC, IHC (p) - ABIN4349794 : Witman, Behm, Ohman, Morrison: ADAR-related activation of adenosine-to-inosine RNA editing during regeneration. in Stem cells and development 2013 (PubMed)

Weitere Antikörper gegen RED1 Interaktionspartner

Human Adenosine Deaminase, RNA-Specific, B1 (ADARB1) Interaktionspartner

  1. 2-way interaction between TPH2 (zeige TDO2 Antikörper) rs4290270 and general traumas revealed that TT homozygotes with history of general traumas had an increased risk for suicide attempt. 3-way interaction of general traumas, TPH2 (zeige TDO2 Antikörper) rs4290270 and ADARB1 rs4819035 indicated that highest predisposition to suicide attempt was observed in individuals who experienced general traumas and were TT homozygote for rs4290270 and TT homozygote for rs4819035.

  2. The range of human disease associated with ADAR1 (zeige ADAR Antikörper) mutations may extend further to include other inflammatory conditions while ADAR2 mutations may affect psychiatric conditions.

  3. Four crystal structures of the human ADAR2 deaminase domain bound to RNA duplexes bearing a mimic of the deamination reaction intermediate.

  4. we determined the importance of specific amino acids at 19 different positions in the ADAR2 5' binding loop and revealed six residues that provide essential structural elements supporting the fold of the loop and key RNA-binding functional groups. This work provided new insight into RNA recognition by ADAR2 and established a new tool for defining structure-function relationships in ADAR (zeige ADAR Antikörper) reactions.

  5. Data indicate that ADAR2 suppresses tumor growth and induces apoptosis by editing and stabilizing IGFBP7 (zeige IGFBP7 Antikörper) in esophageal squamous cell carcinoma.

  6. These findings suggest that adenosine deaminase acting on RNA (zeige ADAR Antikörper) 2 is subject to different regulations by DNA methyltransferase (zeige DNMT1 Antikörper) and histone deacetylase (zeige HDAC1 Antikörper) enzymes in neuronal SH-SY5Y cells.

  7. These data suggest that, like ADAR2, underlying sequences in dsRNA may influence how NF90 (zeige MMP4 Antikörper) recognizes its target RNAs

  8. Detailed structural analysis indicates that the minor groove width of dsRNA and global shape of RNA may play an important role in the specific reading mechanism of ADAR2.

  9. A-to-I RNA editing levels catalyzed by ADAR1 (zeige ADAR Antikörper) and ADARB1 decreased in Alzheimer's disease patients' brain tissues, mainly in the hippocampus and to a lesser degree in the temporal and frontal lobes.

  10. we conclude that this aberrant alternative splicing pattern of ADAR2 downregulates A-to-I editing in glioma

Mouse (Murine) Adenosine Deaminase, RNA-Specific, B1 (ADARB1) Interaktionspartner

  1. ADARB1 mediates adenosine to inosine RNA editing in the testis, and these editing events are dispensable for male fertility in an inbred mouse strain in the lab.

  2. that ADAR2 is a mediator of injury-induced tactile allodynia and thus a potential therapeutic target for the treatment of neuropathic pain

  3. Results show that ADAR2 is important in site-specific changes of protein coding sequences but has relatively modest effects on gene expression and splicing in the adult mouse frontal cortex.

  4. Thus, Adarb1 and Adarb2 (zeige ADARB2 Antikörper) have nearly exclusive expression within brain tissue, while Adar (zeige ADAR Antikörper) has more appreciable expression across multiple tissues.

  5. After fear conditioning protocol, mRNA expression of ADAR2 increased in amygdala and hippocampus, and those mice had a learning-dependent increase in the alternatively spliced inactive form of ADAR2 in the amygdala.

  6. ADAR2 is a key factor for maintaining edited-miRNA population and balancing the expression of several essential miRNAs involved in cancer.

  7. This study clearly demonstrates that ADAR2 influences miRNA abundance and targeting at several levels in the mouse brain.

  8. chronically elevated intraocular pressure in adult mice reduces expression of the ADAR2 enzyme.

  9. Analysis of editing in the filamin A (zeige FLNA Antikörper) encoding mRNA shows very high editing levels outside the nervous system; further shows FLNA (zeige FLNA Antikörper) editing is mainly achieved by ADAR2 but that in some cases ADAR1 (zeige ADAR Antikörper) can efficiently compensate for ADAR2.

  10. Results suggest that ADAR2-reduction is associated with progressive deterioration of nuclear architecture, resulting in vacuolated nuclei due to a Ca2 (zeige CA2 Antikörper)+-permeable AMPA (zeige GRIA3 Antikörper) receptor-mediated mechanism

Zebrafish Adenosine Deaminase, RNA-Specific, B1 (ADARB1) Interaktionspartner

  1. Adar2 Edits the Q/R site of AMPA (zeige GRIA3 Antikörper) receptor Subunit gria2alpha transcript to ensure normal development of nervous system and cranial neural crest cells

RED1 (ADARB1) Antigen-Profil

Protein Überblick

This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.

Genbezeichner und Symbole assoziert mit ADARB1

  • adenosine deaminase, RNA specific B1 (ADARB1) Antikörper
  • adenosine deaminase, RNA-specific, B1 (adarb1) Antikörper
  • adenosine deaminase, RNA-specific, B1 L homeolog (adarb1.L) Antikörper
  • adenosine deaminase, RNA-specific, B1 (Adarb1) Antikörper
  • adenosine deaminase, RNA-specific, B1a (adarb1a) Antikörper
  • 1700057H01Rik Antikörper
  • adar2 Antikörper
  • adarb1 Antikörper
  • AW124433 Antikörper
  • AW558573 Antikörper
  • BB220382 Antikörper
  • D10Bwg0447e Antikörper
  • DRABA2 Antikörper
  • DRADA2 Antikörper
  • red1 Antikörper

Bezeichner auf Proteinebene für ADARB1

adenosine deaminase, RNA-specific, B1 (RED1 homolog rat) , adenosine deaminase, RNA-specific, B1 (RED1 homolog) , adenosine deaminase, RNA-specific, B1 , RNA-specific adenosine deaminase B1 , double-stranded RNA-specific editase 1-like , RED1 homolog , RNA editase , RNA editing deaminase 1 , RNA-editing deaminase 1 , RNA-editing enzyme 1 , adenosine deaminase, RNA-specific, B1 (homolog of rat RED1) , double-stranded RNA-specific editase 1 , dsRNA adenosine deaminase DRADA2 , dsRNA adenosine deaminase , RNA editing deaminase of glutamate receptors , double-stranded RNA-specific editase

GENE ID SPEZIES
521761 Bos taurus
100124739 Xenopus (Silurana) tropicalis
100339367 Oryctolagus cuniculus
100483845 Ailuropoda melanoleuca
100589130 Nomascus leucogenys
495438 Xenopus laevis
374087 Gallus gallus
104 Homo sapiens
487809 Canis lupus familiaris
110532 Mus musculus
25367 Rattus norvegicus
58134 Danio rerio
Ausgewählte Anbieter für anti-RED1 (ADARB1) Antikörper
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