Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) ELISA Kits

AP3B1 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Zusätzlich bieten wir Ihnen AP3B1 Antikörper (38) und AP3B1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
AP3B1 8546 O00203
Anti-Maus AP3B1 AP3B1 11774 Q9Z1T1
Anti-Ratte AP3B1 AP3B1 309969  
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Katalog Nr. Reaktivität Sensitivität Bereich Menge Anbieter Lieferzeit Preis Details
Human 0.064 ng/mL 0.15-10 ng/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
592,59 €
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Weitere ELISA Kits für AP3B1 Interaktionspartner

Human Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) Interaktionspartner

  1. Synergistic defects of UNC13D (zeige UNC13D ELISA Kits) and AP3B1 leading to adult hemophagocytic lymphohistiocytosis.

  2. Using a co-affinity purification strategy, authors have identified the beta subunit (zeige POLG ELISA Kits) of the AP-3 adapter protein (zeige TOLLIP ELISA Kits) complex, AP3B1, as a binding partner for the M proteins of the zoonotic paramyxoviruses Nipah virus and Hendra virus.

  3. Data indicate that RUN and FYVE domain protein Rabip4'(RUFY1 (zeige RUFY1 ELISA Kits)) interacts specifically and directly with adaptor protein complex AP-3.

  4. The study provides a description of two unrelated individuals with Hermansky Pudlak syndrome type 2 associated with novel mutations in AP3B1.

  5. diphosphoinositol pentakisphosphate-mediated pyrophosphorylation of AP3B1 modulates the interaction with Kif3A (zeige KIF3A ELISA Kits) and, as a consequence, affects the release of HIV-1 virus-like particles.

  6. Two nonsense mutations in ADTB3A, C1578T (R-->X) and G2028T (E-->X), result in lack of ADTB3A mRNA and beta3A (zeige BHLHE22 ELISA Kits) protein production and a severe, G-CSF (zeige CSF3 ELISA Kits)-responsive neutropenia in addition to oculocutaneous albinism and platelet storage pool deficiency.

  7. Description of mutations in HPS (zeige HPS1 ELISA Kits) genes that cause Hermansky-Pudlak syndrome (review)

  8. We defined a homozygous genomic deletion in AP3B1, the gene encoding the beta chain of the adaptor protein-3 (AP-3) complex. The mutation leads to in-frame skipping of exon 15 and thus perturbs proper assembly of the heterotetrameric AP-3 complex.

  9. A novel homozygous mutation in AP3B1 was detected in a 2-year-old patient with oculocutaneous albinism and immunodeficiency with Hermansky-Pudlak syndrome type II and eventual acute fatal hemophagocytic lymphohistiocytosis.

  10. Mutations in AP3B1 is not associated with familial hemophagocytic lymphohistiocytosis

Mouse (Murine) Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) Interaktionspartner

  1. HIV-2 particle release was dependent on the adaptor protein complex AP-3 and the newly identified AP-5 (zeige AP5B1 ELISA Kits) complex, but much less so on AP-1 (zeige JUN ELISA Kits).

  2. Data show that cytokine activation as a result of toll-like receptor 2 (TLR2 (zeige TLR2 ELISA Kits)) stimulation occurs at different intracellular locations and is mediated by the phagosomal trafficking molecule adaptor protein-3 (zeige HSPB3 ELISA Kits) (AP-3).

  3. Our study indicates that Ap3b1 gene play distinct roles in melanin production and tyrosinase (zeige TYR ELISA Kits) distribution compared with Hps1 gene.

  4. we show that loss of the related adaptor protein AP-1 has a similar effect on regulated secretion but exacerbates the effect of AP-3 RNAi, suggesting distinct roles for the two adaptors in the regulated secretory pathway.

  5. Data suggest functional links between OCA2 and the BLOC-1, BLOC-2, and AP-3 protein complexes involved in melanosome biogenesis.

  6. The identification of the feeble mutation led to our subsequent observations that AP-3, as well as the BLOC-1 (zeige PLDN ELISA Kits) and BLOC-2 (zeige HPS6 ELISA Kits) are essential for plasmacytoid dendritic cells signaling through TLR7 (zeige TLR7 ELISA Kits) and TLR9 (zeige TLR9 ELISA Kits).

  7. TLR9 (zeige TLR9 ELISA Kits) signals leading to activation of IFN I, require TLR9 (zeige TLR9 ELISA Kits) trafficking from endosomes to lysosome-related organelle; adapter protein (zeige GRB10 ELISA Kits)-3 (zeige HSPB3 ELISA Kits) identified as protein complex responsible for trafficking of TLR9 (zeige TLR9 ELISA Kits) to this subcellular compartment

  8. AP-3 mediates the intracellular trafficking of CD1d (zeige CD1D ELISA Kits) to lysosomes for sampling of lipid antigens (Ags (zeige GLA ELISA Kits)) involved in self-Ag presentation and thymocyte-positive selection.

  9. AP-3 requirement is a particular attribute of the CD1d (zeige CD1D ELISA Kits) pathway in mice and that, although MHC class II molecules and CD1d (zeige CD1D ELISA Kits) are both found in late endosomes or lysosomes, different pathways mediate their intracellular trafficking

  10. AP-3B (zeige AP3M2 ELISA Kits) plays a critical role in the normal formation and function of a subset of synaptic vesicles

AP3B1 Antigen-Profil

Beschreibung des Gens

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit AP3B1

  • adaptor-related protein complex 3, beta 1 subunit (ap3b1) Antikörper
  • adaptor-related protein complex 3, beta 1 subunit (AP3B1) Antikörper
  • adaptor-related protein complex 3, beta 1 subunit (LOC100350054) Antikörper
  • adaptor-related protein complex 3, beta 1 subunit (Ap3b1) Antikörper
  • ADTB3 Antikörper
  • ADTB3A Antikörper
  • AP-3 Antikörper
  • AP3B1 Antikörper
  • AU015684 Antikörper
  • beta3A Antikörper
  • C78395 Antikörper
  • cb964 Antikörper
  • HPS Antikörper
  • Hps2 Antikörper
  • pe Antikörper
  • pearl Antikörper
  • rim2 Antikörper

Bezeichner auf Proteinebene für AP3B1

adaptor-related protein complex 3, beta 1 subunit , AP-3 complex subunit beta-1 , adaptor-related protein complex 3, beta-1 subunit , AP-3 complex subunit beta-1-like , AP-3 complex beta-3A subunit , adaptor protein complex AP-3 subunit beta-1 , beta-3A-adaptin , clathrin assembly protein complex 3 beta-1 large chain , adapter-related protein complex 3 subunit beta-1 , adaptor protein complex AP-3 beta-1 subunit , adaptor-related protein complex AP-3, beta 1 subunit , beta3A-adaptin , recombination induced mutation 2 , adaptor-related protein complex AP3 beta 1 subunit

GENE ID SPEZIES
443724 Xenopus laevis
386770 Danio rerio
427646 Gallus gallus
461789 Pan troglodytes
100019944 Monodelphis domestica
100049670 Sus scrofa
100065436 Equus caballus
100226392 Taeniopygia guttata
100350054 Oryctolagus cuniculus
100397094 Callithrix jacchus
100584809 Nomascus leucogenys
708754 Macaca mulatta
8546 Homo sapiens
11774 Mus musculus
309969 Rattus norvegicus
767602 Bos taurus
403459 Canis lupus familiaris
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