anti-Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) Antikörper

AP3B1 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Zusätzlich bieten wir Ihnen AP3B1 Proteine (3) und AP3B1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
AP3B1 8546 O00203
AP3B1 11774 Q9Z1T1
AP3B1 309969  
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Top anti-AP3B1 Antikörper auf antikoerper-online.de

Showing 10 out of 39 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert IHC (p) Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Ziege Unkonjugiert IHC (p) Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$500.50
Details
Human Kaninchen Unkonjugiert WB Western Blot: AP3B1 Antibody [NBP1-33723] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged AP3B1 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert ELISA, WB The AP3 Antibody is used in Western blot to detect AP3 in HeLa cell lysates. 0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$327.00
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert WB Ap3b1 antibody used at 2.5 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$473.93
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cells, using AP3B1 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged AP3B1 is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details

AP3B1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , , , ,
, ,
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-AP3B1 Antikörper

  1. Cow (Bovine) Polyclonal AP3B1 Primary Antibody für WB - ABIN2778057 : Kuwahara, Inoue, DAgati, Fujimoto, Eguchi, Saha, Wolozin, Iwatsubo, Abeliovich: LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts. in Scientific reports 2016 (PubMed)

Weitere Antikörper gegen AP3B1 Interaktionspartner

Human Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) Interaktionspartner

  1. Synergistic defects of UNC13D (zeige UNC13D Antikörper) and AP3B1 leading to adult hemophagocytic lymphohistiocytosis.

  2. Using a co-affinity purification strategy, authors have identified the beta subunit (zeige POLG Antikörper) of the AP-3 adapter protein (zeige TOLLIP Antikörper) complex, AP3B1, as a binding partner for the M proteins of the zoonotic paramyxoviruses Nipah virus and Hendra virus.

  3. Data indicate that RUN and FYVE domain protein Rabip4'(RUFY1 (zeige RUFY1 Antikörper)) interacts specifically and directly with adaptor protein complex AP-3.

  4. The study provides a description of two unrelated individuals with Hermansky Pudlak syndrome type 2 associated with novel mutations in AP3B1.

  5. diphosphoinositol pentakisphosphate-mediated pyrophosphorylation of AP3B1 modulates the interaction with Kif3A (zeige KIF3A Antikörper) and, as a consequence, affects the release of HIV-1 virus-like particles.

  6. Two nonsense mutations in ADTB3A, C1578T (R-->X) and G2028T (E-->X), result in lack of ADTB3A mRNA and beta3A (zeige BHLHE22 Antikörper) protein production and a severe, G-CSF (zeige CSF3 Antikörper)-responsive neutropenia in addition to oculocutaneous albinism and platelet storage pool deficiency.

  7. Description of mutations in HPS (zeige HPS1 Antikörper) genes that cause Hermansky-Pudlak syndrome (review)

  8. We defined a homozygous genomic deletion in AP3B1, the gene encoding the beta chain of the adaptor protein-3 (AP-3) complex. The mutation leads to in-frame skipping of exon 15 and thus perturbs proper assembly of the heterotetrameric AP-3 complex.

  9. A novel homozygous mutation in AP3B1 was detected in a 2-year-old patient with oculocutaneous albinism and immunodeficiency with Hermansky-Pudlak syndrome type II and eventual acute fatal hemophagocytic lymphohistiocytosis.

  10. Mutations in AP3B1 is not associated with familial hemophagocytic lymphohistiocytosis

Mouse (Murine) Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) Interaktionspartner

  1. HIV-2 particle release was dependent on the adaptor protein complex AP-3 and the newly identified AP-5 complex, but much less so on AP-1 (zeige JUN Antikörper).

  2. Data show that cytokine activation as a result of toll-like receptor 2 (TLR2 (zeige TLR2 Antikörper)) stimulation occurs at different intracellular locations and is mediated by the phagosomal trafficking molecule adaptor protein-3 (zeige HSPB3 Antikörper) (AP-3).

  3. Our study indicates that Ap3b1 gene play distinct roles in melanin production and tyrosinase (zeige TYR Antikörper) distribution compared with Hps1 gene.

  4. we show that loss of the related adaptor protein AP-1 has a similar effect on regulated secretion but exacerbates the effect of AP-3 RNAi, suggesting distinct roles for the two adaptors in the regulated secretory pathway.

  5. Data suggest functional links between OCA2 and the BLOC-1, BLOC-2, and AP-3 protein complexes involved in melanosome biogenesis.

  6. The identification of the feeble mutation led to our subsequent observations that AP-3, as well as the BLOC-1 (zeige PLDN Antikörper) and BLOC-2 (zeige HPS6 Antikörper) are essential for plasmacytoid dendritic cells signaling through TLR7 (zeige TLR7 Antikörper) and TLR9 (zeige TLR9 Antikörper).

  7. TLR9 (zeige TLR9 Antikörper) signals leading to activation of IFN I, require TLR9 (zeige TLR9 Antikörper) trafficking from endosomes to lysosome-related organelle; adapter protein (zeige GRB10 Antikörper)-3 (zeige HSPB3 Antikörper) identified as protein complex responsible for trafficking of TLR9 (zeige TLR9 Antikörper) to this subcellular compartment

  8. AP-3 mediates the intracellular trafficking of CD1d (zeige CD1D Antikörper) to lysosomes for sampling of lipid antigens (Ags (zeige GLA Antikörper)) involved in self-Ag presentation and thymocyte-positive selection.

  9. AP-3 requirement is a particular attribute of the CD1d (zeige CD1D Antikörper) pathway in mice and that, although MHC class II molecules and CD1d (zeige CD1D Antikörper) are both found in late endosomes or lysosomes, different pathways mediate their intracellular trafficking

  10. AP-3B (zeige AP3M2 Antikörper) plays a critical role in the normal formation and function of a subset of synaptic vesicles

AP3B1 Antigen-Profil

Protein Überblick

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit AP3B1

  • adaptor related protein complex 3 beta 1 subunit L homeolog (ap3b1.L) Antikörper
  • adaptor-related protein complex 3, beta 1 subunit a (ap3b1a) Antikörper
  • adaptor related protein complex 3 beta 1 subunit (AP3B1) Antikörper
  • adaptor-related protein complex 3, beta 1 subunit (Ap3b1) Antikörper
  • ADTB3 Antikörper
  • ADTB3A Antikörper
  • AP-3 Antikörper
  • AP3B1 Antikörper
  • AU015684 Antikörper
  • beta3A Antikörper
  • C78395 Antikörper
  • cb964 Antikörper
  • HPS Antikörper
  • Hps2 Antikörper
  • pe Antikörper
  • pearl Antikörper
  • rim2 Antikörper

Bezeichner auf Proteinebene für AP3B1

adaptor-related protein complex 3, beta 1 subunit , AP-3 complex subunit beta-1 , adaptor-related protein complex 3, beta-1 subunit , AP-3 complex subunit beta-1-like , AP-3 complex beta-3A subunit , adaptor protein complex AP-3 subunit beta-1 , beta-3A-adaptin , clathrin assembly protein complex 3 beta-1 large chain , adapter-related protein complex 3 subunit beta-1 , adaptor protein complex AP-3 beta-1 subunit , adaptor-related protein complex AP-3, beta 1 subunit , beta3A-adaptin , recombination induced mutation 2 , adaptor-related protein complex AP3 beta 1 subunit

GENE ID SPEZIES
443724 Xenopus laevis
386770 Danio rerio
427646 Gallus gallus
461789 Pan troglodytes
100019944 Monodelphis domestica
100049670 Sus scrofa
100065436 Equus caballus
100226392 Taeniopygia guttata
100350054 Oryctolagus cuniculus
100397094 Callithrix jacchus
100584809 Nomascus leucogenys
708754 Macaca mulatta
8546 Homo sapiens
11774 Mus musculus
309969 Rattus norvegicus
767602 Bos taurus
403459 Canis lupus familiaris
Ausgewählte Anbieter für anti-AP3B1 (AP3B1) Antikörper
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