anti-Activin Receptor Type I (ACRV1) Antikörper

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Zusätzlich bieten wir Ihnen Activin Receptor Type I Proteine (35) und Activin Receptor Type I Kits (15) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ACRV1 11477 P37172
ACRV1 90 Q04771
ACRV1 79558 P80201
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Top anti-Activin Receptor Type I Antikörper auf antikoerper-online.de

Showing 10 out of 168 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-ACVR1 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate Immunohistochemistry with Kidney tissue at an antibody concentration of 5µg/ml using anti-ACVR1 antibody (ARP45040_P050) 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit  Target Name: ACVR1  Sample Tissue: Human Fetal Heart  Antibody Dilution: 1.0 µg/mL Host: Rabbit  Target Name: ACVR1  Sample Tissue: Human Fetal Lung  Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of ACVR1 (arrow) using rabbit polyclonal ACVR1 Antibody (Center) (ABIN657777). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ACVR1 gene. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of ACVR1 (arrow) using rabbit polyclonal ACVR1 Antibody (Center N153) (ABIN391154). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ACVR1 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-ACVR1 Pab (ABIN391156) in mouse brain tissue lysate. ACVR1(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-ACVR1 Pab (ABIN392240) is used in Western blot to detect ACVR1 in HeLa cell lysate (Lane 1) and mouse liver tissue lysate (Lane 2). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma Western blot analysis of anti-ACVR1 Pab (ABIN391155) in mouse brain tissue lysate.ACVR1(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN238620 (0.3µg/ml) staining of Human Umbilical Cord lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Western blot analysis of anti-ACVR1 Pab in mouse brain tissue lysate.ACVR1(arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of anti-ACVR1 Pab in mouse brain tissue lysate. ACVR1(arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details

ACRV1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Activin Receptor Type I Antikörper

  1. Human Polyclonal ACRV1 Primary Antibody für EIA, IHC (p) - ABIN359223 : Casagrandi, Bearfield, Geary, Redman, Muttukrishna: Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia. in Molecular human reproduction 2003 (PubMed)
    Zeige alle 5 Referenzen für 359223

  2. Human Polyclonal ACRV1 Primary Antibody für EIA, WB - ABIN359224 : Welt: The physiology and pathophysiology of inhibin, activin and follistatin in female reproduction. in Current opinion in obstetrics & gynecology 2002 (PubMed)
    Zeige alle 5 Referenzen für 359224

  3. Human Polyclonal ACRV1 Primary Antibody für IHC (p), WB - ABIN392240 : ten Dijke, Ichijo, Franzén, Schulz, Saras, Toyoshima, Heldin, Miyazono: Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity. in Oncogene 1993 (PubMed)
    Zeige alle 4 Referenzen für 392240

  4. Human Polyclonal ACRV1 Primary Antibody für WB - ABIN657777 : Canzian, Cox, Setiawan, Stram, Ziegler, Dossus, Beckmann, Blanché, Barricarte, Berg, Bingham, Buring, Buys, Calle, Chanock, Clavel-Chapelon, DeLancey, Diver, Dorronsoro, Haiman, Hallmans, Hankinson, Hunter, Hüsing, Isaacs, Khaw, Kolonel, Kraft, Le Marchan: Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium. in Human molecular genetics 2010 (PubMed)
    Zeige alle 4 Referenzen für 657777

  5. Human Polyclonal ACRV1 Primary Antibody für IHC, ELISA - ABIN238620 : Shore, Xu, Feldman, Fenstermacher, Cho, Choi, Connor, Delai, Glaser, LeMerrer, Morhart, Rogers, Smith, Triffitt, Urtizberea, Zasloff, Brown, Kaplan: A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. in Nature genetics 2006 (PubMed)

  6. Human Polyclonal ACRV1 Primary Antibody für WB - ABIN391156 : Kan, Liu, McGuire, Berger, Awatramani, Dymecki, Kessler: Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification. in Stem cells (Dayton, Ohio) 2009 (PubMed)

  7. Cow (Bovine) Polyclonal ACRV1 Primary Antibody für WB - ABIN2782108 : Kariyawasam, Xanthou, Barkans, Aizen, Kay, Robinson: Basal expression of bone morphogenetic protein receptor is reduced in mild asthma. in American journal of respiratory and critical care medicine 2008 (PubMed)

Weitere Antikörper gegen Activin Receptor Type I Interaktionspartner

Mouse (Murine) Activin Receptor Type I (ACRV1) Interaktionspartner

  1. The authors demonstrated that ubiquitin-specific protease (USP) 4 (zeige USP4 Antikörper) strongly induces activin (zeige Actbeta Antikörper)/BMP signaling by removing the inhibitory monoubiquitination from SMAD4 (zeige SMAD4 Antikörper).

  2. Enhanced SMAD (zeige SMAD1 Antikörper)-dependent BMP signaling through constitutively active ACVR1 in palatal epithelium causes submucous cleft palate in mice, via medial-edge-epithelium persistence presumably due to the up regulation of DeltaNp63 andresultingreductionofcaspase-3 activation. 2.

  3. BMP signaling mediated by coordination of ALK2/ACVR1, ALK3/BMPR1A (zeige BMPR1A Antikörper), and BMPR2 (zeige BMPR2 Antikörper) is an essential proangiogenic cue for retinal vessels.

  4. This study showed that Gja1 (zeige GJA1 Antikörper) may act downstream of cAMP-PKA signal to mediate the effects of Acvr1 on the differentiation of uterine stromal cells through targeting Hand2 (zeige HAND2 Antikörper).

  5. Results showed activin (zeige Actbeta Antikörper)-C and follistatin (zeige FST Antikörper) are differentially expressed during prostate development and suggested that the antagonistic property of follistatin (zeige FST Antikörper) is secondary to the action of activin (zeige Actbeta Antikörper)-C. Study provides evidence to support a role of activin (zeige Actbeta Antikörper)-C in prostate development and provides new insights in the spatiotemporal localization of activins and their antagonists during mouse prostate development.

  6. BMPR1B plays distinct roles from BMPR1A and ACVR1 in maintaining bone mass and transducing BMP signaling

  7. Suggest that BMP signaling upregulates the calcineurin/nuclear factor of activated T cell (zeige NFATC3 Antikörper) pathway via BMP type I receptor ALK2, contributing to cardiac hypertrophy and fibrosis.

  8. results suggest that ACVR1(R206H) causes FOP (zeige CHTOP Antikörper) by gaining responsiveness to the normally antagonistic ligand activin A (zeige INHBA Antikörper), demonstrating that this ligand is necessary and sufficient for driving HO in a genetically accurate model of FOP (zeige CHTOP Antikörper)

  9. The findings suggest that the mutant ALK2 related to Fibrodysplasia ossificans progressiva is enhanced by bone morphogenetic protein type II receptors via the T203-regulated phosphorylation of ALK2.

  10. ACVR1 is required for chondrocyte proliferation and differentiation, particularly in craniofacial and axial elements, but exerts coordinated functions with both BMPR1A (zeige BMPR1A Antikörper) and BMPR1B (zeige BMPR1B Antikörper) throughout the developing endochondral skeleton

Human Activin Receptor Type I (ACRV1) Interaktionspartner

  1. Data suggest BMP9/GDF2 (zeige GDF2 Antikörper) and BMP10 (zeige BMP10 Antikörper) synergize with TNFA (zeige TNF Antikörper) to increase monocyte recruitment to vascular endothelial cells; process appears to be mediated mainly via ALK2/ACVR1 (which exhibits protein kinase (zeige CDK7 Antikörper) activity). These studies used in vitro flow monocyte adhesion assay. (BMP9 (zeige GDF2 Antikörper) = growth differentiation factor 2 (zeige GDF2 Antikörper); BMP10 (zeige BMP10 Antikörper) = bone morphogenetic protein 10 (zeige BMP10 Antikörper); TNFA (zeige TNF Antikörper) = tumor necrosis factor alpha (zeige TNF Antikörper); ALK2/ACVR1 = activin A receptor type 1)

  2. The effects of ACVR1/ALK2 mutations causing fibrodysplasia ossificans progressiva are extended to the central nervous system. Brainstem hamartomatous lesions and dysmorphisms, variably associated with dentate nucleus and basal ganglia signal abnormalities and/or calcifications, may represent useful disease hallmarks.

  3. Low ALK2 expression is associated with invasiveness of breast cancer.

  4. Further investigation on clinical ESCC samples and non-tumorous adjacent tissue found that tumors with triple-positive BMP6 (zeige BMP6 Antikörper), ALK2 and BMPRII (zeige BMPR2 Antikörper) had deeper growth than tumors with only BMP6 (zeige BMP6 Antikörper) expression

  5. The clinical manifestations, the disease course, and the molecular findings of involvement of ACVR1 gene in this family are suggestive of "FOP variant" or an unusual ACVR1-related skeletal dysplasia

  6. Activin-A (zeige INHBA Antikörper) is increased in the airway of asthmatics and peaks during asthma exacerbations.Activin-A signalling pathways are dysregulated in severe asthma.

  7. Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders.

  8. The higher PE activin A (zeige INHBA Antikörper) concentrations resulted in abnormal endothelial functions, which may contribute to the systemic maternal vascular endothelial cell dysfunction observed in the disorder.

  9. A report of two patients has been presented with multi-system involvement in a severe variant of fibrodysplasia ossificans progressiva caused by the ACVR1 c.772G>A; R258G mutation.

  10. Fibrodysplasia ossificans progressiva-ACVR1 abnormally transduces bone morphogenetic protein signaling in response to Activin-A (zeige INHBA Antikörper).

Activin Receptor Type I (ACRV1) Antigen-Profil

Protein Überblick

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Genbezeichner und Symbole assoziert mit ACRV1

  • activin A receptor, type 1 (Acvr1) Antikörper
  • activin A receptor, type I (ACVR1) Antikörper
  • activin A receptor, type I (Acvr1) Antikörper
  • ActR-I Antikörper
  • ActR-IA Antikörper
  • ACTRI Antikörper
  • ActRIA Antikörper
  • Acvr Antikörper
  • ACVR1A Antikörper
  • ACVRLK2 Antikörper
  • Alk-2 Antikörper
  • ALK2 Antikörper
  • Alk8 Antikörper
  • D330013D15Rik Antikörper
  • FOP Antikörper
  • SKR1 Antikörper
  • Tsk7L Antikörper
  • TSRI Antikörper

Bezeichner auf Proteinebene für ACRV1

TGF-B superfamily receptor type I , TSK-7L , TSR-I , activin receptor type I , activin receptor type-1 , serine/threonine-protein kinase receptor R1 , activin A receptor, type II-like kinase 2 , activin receptor-like kinase 2 , hydroxyalkyl-protein kinase , ACTR-I , SKR1 , activin A receptor, type 1 , activin type I receptor , type I TGF B receptor , activin A receptor, type I , activin receptor type IA

GENE ID SPEZIES
11477 Mus musculus
90 Homo sapiens
478757 Canis lupus familiaris
338068 Bos taurus
79558 Rattus norvegicus
395246 Gallus gallus
443161 Ovis aries
Ausgewählte Anbieter für anti-Activin Receptor Type I (ACRV1) Antikörper
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