anti-Activin A Receptor, Type IIA (ACVR2A) Antikörper

ACVR2A encodes activin A type II receptor. Zusätzlich bieten wir Ihnen Activin Receptor Type IIA Proteine (37) und Activin Receptor Type IIA Kits (14) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ACVR2A 92 P27037
ACVR2A 29263 P38444
ACVR2A 11480 P27038
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (LEFT)Western blot analysis of anti-ACVR2A Antibody (N-term) in mouse liver brain and kidney tissue lysates (35ug/lane). ACVR2A (arrow) was detected using the purified Pab. (RIGHT)Western blot analysis of ACVR2A (arrow) using rabbit polyclonal ACVR2A Antibody 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-ACVR2A Antibody (N-term) (ABIN391160) in mouse liver brain and kidney tissue lysates (35 µg/lane). ACVR2A (arrow) was detected using the purified polyclonal antibody. Western blot analysis of ACVR2A (arrow) using rabbit polyclonal ACVR2A Antibody (N-term) (ABIN391160). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ACVR2A gene (Lane 2) (Origene Technologies). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Unkonjugiert IHC (p), WB   100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
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Human Kaninchen Unkonjugiert WB Western Blot: Activin RIIA Antibody [NBP1-33601] - Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 7. 5% SDS PAGE; antibody diluted at 1:10000. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.2 mL Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
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Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti ARIP2B Polyclonal Antibody, Unconjugated (ABIN728383) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Lane 1: mouse testis lysates Lane 2: mouse brain lysates probed with Anti ARIP2a Polyclonal Antibody, Unconjugated (ABIN728383) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 57kD. Observed band size: 57kD. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
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Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
333,33 €
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Rind (Kuh) Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
400,00 €
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Rind (Kuh) Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
400,00 €
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Maus Kaninchen Unkonjugiert WB Mouse Acvr2a Antibody (N-term)  western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Acvr2a antibody detected the Acvr2a protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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ACVR2A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)


Mouse (Murine)


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Weitere Antikörper gegen Activin Receptor Type IIA Interaktionspartner

Human Activin A Receptor, Type IIA (ACVR2A) Interaktionspartner

  1. TGF-beta (zeige TGFB1 Antikörper) receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.(

  2. This locus harbors an evolutionary conserved gene-desert region with non-coding intergenic sequences likely involved in regulation of protein-coding flanking genes ZEB2 (zeige ZEB2 Antikörper) and ACVR2A. This region is intensively studied for mutations causing severe developmental/genetic disorders. Our analyses indicate a promising target region for interventions aimed to reduce risks of many major human diseases and mortality.

  3. Data suggest ALK1 (zeige ACVRL1 Antikörper) and ACVR2A/ACVR2B (zeige ACVR2B Antikörper), acting as BMP9 (zeige GDF2 Antikörper) co-receptors, rearrange pro-domains of BMP9 (zeige GDF2 Antikörper)--pro-domain dimer complex leading to displacement of pro-domains after receptor binding, release of mature non-dimer BPM9, and activation of signaling.

  4. Activin A (zeige INHBA Antikörper) inhibited signaling by BMP-6 (zeige BMP6 Antikörper) and BMP-9 (zeige GDF2 Antikörper) by competing for type 2 receptors ACVR2A and ACVR2B (zeige ACVR2B Antikörper).

  5. Data suggest that an SNP in promoter region of ACVR2A (rs1424954, the pre-eclampsia susceptibility allele) down-regulates 1) expression of ACVR2A in trophoblasts and 2) signal transduction in response to excess activin-A (zeige INHBA Antikörper) (as seen in pre-eclampsia).

  6. Adenomyotic tissues express high levels of myostatin (zeige MSTN Antikörper), follistatin (zeige FST Antikörper), and activin (zeige Actbeta Antikörper) type II receptors.

  7. The gene ACVR2A was associated with the more severe early onset preeclampsia.

  8. For ACVR2A SNPs (rs10497025, rs1128919, rs13430086), no statistically significant difference was found between preeclampsia and control groups in terms of genotype and allele frequencies.

  9. ACVR2A was identified as a subnetwork component in functional association network analysis.

  10. ACVR2A showed statistically significant differential dose-expression relationship.

Cow (Bovine) Activin A Receptor, Type IIA (ACVR2A) Interaktionspartner

  1. This genome-wide association study identified variants in the upstream region of ACVR2A, which were associated with female fertility in Japanese Black cattle.

Zebrafish Activin A Receptor, Type IIA (ACVR2A) Interaktionspartner

  1. Roles in hindbrain and neural crest cell (NCC) patterning, in NCC derived pharyngeal arch cartilage and joint formation, and in tooth development.

Mouse (Murine) Activin A Receptor, Type IIA (ACVR2A) Interaktionspartner

  1. Anti-ActRII blockade is an effective intervention against cancer cachexia providing benefit even in the presence of anti-cancer therapies.

  2. Data, including data from studies using transgenic mice, suggest that osteoblasts deficient in Acvr2A exhibit un-characteristic features; osteoclasts deficient in Acvr2A or Acvr2B (zeige ACVR2B Antikörper) or both appear normal. Acvr2A-deficient mice exhibit significantly increased femoral trabecular bone volume at 6 weeks of age; Acvr2B (zeige ACVR2B Antikörper)-deficient mice exhibit no significant change in any bone parameter.

  3. miR (zeige MLXIP Antikörper)-125b regulated the activin (zeige Actbeta Antikörper)/Smad2 (zeige SMAD2 Antikörper) signaling in neonatal mouse ovary by directly targeting the 3'-untranslated region of activin receptor type 2a

  4. Our study shows that a miR (zeige MLXIP Antikörper)-590/Acvr2a/Rad51b (zeige Rad51B Antikörper) signaling axis ensures the stabilization of mESCs by balancing DNA damage repair and rapid proliferation during self-renewal.

  5. Bmpr2 (zeige BMPR2 Antikörper) and Acvr2a normally play cell-type-specific, necessary roles in organelle biogenesis and the shutdown of developmental programs and cell division.

  6. Acvr2a is a Th17 specific gene making Th17 cells distinct from other helper T cells, Th1 (zeige HAND1 Antikörper), Th2, and Treg.

  7. stimulates expression of APRIL via the Smad3 (zeige SMAD3 Antikörper) and ERK (zeige EPHB2 Antikörper)/CREB (zeige CREB1 Antikörper) pathways in macrophages

  8. Results demonstrated that BMPRII (zeige BMPR2 Antikörper) and ActRII are the functional type II TGF-beta (zeige TGFB1 Antikörper) receptors in BMP-9 (zeige GDF2 Antikörper)-induced osteogenic differentiation of C3H10T1/2 cells.

  9. The coordinated activity of ActRIIA and BMPRII (zeige BMPR2 Antikörper) receptor subunits selectively mediates the chemotactic response to BMP7 (zeige BMP7 Antikörper).

  10. Activin (zeige Actbeta Antikörper) type IIB(ActRIIB (zeige ACVR2B Antikörper)) and its subfamily receptor, Activin (zeige Actbeta Antikörper) type IIA (ActRIIA), cooperatively mediate the Gdf11 (zeige GDF11 Antikörper) signal in patterning the axial vertebrae

Activin Receptor Type IIA (ACVR2A) Antigen-Profil

Protein Überblick

This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

Genbezeichner und Symbole assoziert mit ACVR2A

  • activin A receptor, type IIA (ACVR2A) Antikörper
  • activin A receptor, type IIA (acvr2a) Antikörper
  • activin A receptor, type IIA (LOC100224301) Antikörper
  • activin A receptor, type IIA (Acvr2a) Antikörper
  • activin A receptor, type IIAa (acvr2aa) Antikörper
  • activin receptor IIA (Acvr2a) Antikörper
  • actr2a Antikörper
  • ACTRII Antikörper
  • ActrIIa Antikörper
  • Acvr2 Antikörper
  • acvr2a Antikörper
  • rActR-II Antikörper
  • TactrII Antikörper
  • wu:fa02e10 Antikörper
  • XSTK9 Antikörper

Bezeichner auf Proteinebene für ACVR2A

activin receptor IIA , activin receptor type-2A , activin A receptor, type IIA , ACTR-IIA , activin receptor type IIA , type II activin receptor , activin A receptor, type II , activin receptor, type IIA , ACTRIIA , activin receptor type II , activin type 2 receptor , activin receptor IIa , etID22865.9

GENE ID SPEZIES
397282 Sus scrofa
476140 Canis lupus familiaris
100216172 Xenopus (Silurana) tropicalis
100224301 Taeniopygia guttata
100583170 Nomascus leucogenys
92 Homo sapiens
29263 Rattus norvegicus
281598 Bos taurus
396324 Gallus gallus
443304 Ovis aries
399283 Xenopus laevis
553359 Danio rerio
11480 Mus musculus
Ausgewählte Anbieter für anti-Activin Receptor Type IIA (ACVR2A) Antikörper
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