Activin A Receptor, Type IB Proteine (ACVR1B)

ACVR1B encodes an activin A type IB receptor. Zusätzlich bieten wir Ihnen Activin A Receptor Type IB Antikörper (151) und Activin A Receptor Type IB Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ACVR1B 11479 Q61271
ACVR1B 91 P36896
ACVR1B 29381 P80202
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Showing 10 out of 28 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,244.78
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
HEK-293 Cells Human Fc Tag Human Activin RIB, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. Immobilized Human Activin A, Tag Free  with a linear range of 0.3-2.5 μg/mL. 200 μg Anmelden zum Anzeigen 2 bis 3 Tage
$275.00
Details
Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$161.70
Details
Mammalian Cells Maus Fc Tag   50 μg Anmelden zum Anzeigen 4 Days
$248.33
Details
Human Cells Rhesusaffen Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Human Cells Human Fc Tag,His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$250.80
Details
Human Cells Maus Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Human Cells Ratte Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Human Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$137.50
Details

ACVR1B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) , , ,
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Human , , , , , , , ,
, , , ,
Rat (Rattus) ,
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Weitere Proteine zu Activin A Receptor, Type IB (ACVR1B) Interaktionspartnern

Mouse (Murine) Activin A Receptor, Type IB (ACVR1B) Interaktionspartner

  1. Our results demonstrate that ALK4 haploinsufficiency ameliorates cardiac fibrosis and dysfunction in a mouse pressure-overload model associated with inhibition of cardiac fibroblast activation and cardiomyocyte apoptosis through the suppression of Smad2 (zeige SMAD2 Proteine)/3 activity.

  2. ALK4 is an important profibrotic signaling molecule in the post-MI CF. Haplodeficiency of ALK4 significantly improved LV function and survival rate by attenuating CF in vivo, ameliorated

  3. Uterine Activin-Like Kinase 4 Regulates Trophoblast Development During Mouse Placentation

  4. These results indicate that an appropriate level of activin signaling may be required for GSIS in pancreatic beta cells, and that activin signaling involves modulation of KATP channel activity.

  5. Signaling through the TGF beta (zeige TGFB1 Proteine)-activin receptors ALK4/5/7 regulates testis formation and male germ cell development.

  6. identified ACVRIB as a direct target of miR (zeige MLXIP Proteine)-145. The ectopic expression of miR (zeige MLXIP Proteine)-145 reduced the levels of both ACVRIB mRNA and protein and also interfered with activin-induced Smad2 (zeige SMAD2 Proteine) phosphorylation.

  7. Results identify a molecular mechanism that explains the cell-type specific aspects of signaling by myostatin (zeige MSTN Proteine), ALK4, ALK5 (zeige TGFBR1 Proteine), and other TGF-beta (zeige TGFB1 Proteine) family members.

  8. Inhibin alpha-subunit N terminus interacts with activin type IB receptor to disrupt activin signaling.

  9. Knockdown or pharmacological inhibition of the Nodal/Activin receptor Alk4/7 in cancer stem cells virtually abrogated their self-renewal capacity and in vivo tumorigenicity

  10. Our analysis of this Acvr1b knockout mouse line provides direct genetic evidence that Acvr1b signaling is required for both hair follicle development and cycling.

Human Activin A Receptor, Type IB (ACVR1B) Interaktionspartner

  1. It was concluded that ALK4 inhibition increases myogenesis but also regulates the tight balance of protein synthesis and degradation.

  2. in a relatively large cohort of athletes from Europe and South America we have shown that the ACVR1B rs2854464 A allele is associated with sprint/power performance in Caucasians but not in Brazilian athletes.

  3. ALK4 is an important profibrotic signaling molecule in the post-MI CF. Haplodeficiency of ALK4 significantly improved LV function and survival rate by attenuating CF in vivo, ameliorated

  4. ALK4 is expressed in male germ cells and Sertoli cells.

  5. This study demonstrated positive regulation of monocyte/macrophage differentiation by lnc-MC and uncovered an elaborate regulation mechanism composed of PU.1, lnc-MC, miR (zeige MLXIP Proteine)-199a-5p, and ACVR1B.

  6. Data suggest that activin A (zeige INHBA Proteine) up-regulates SNAIL (zeige SNAI1 Proteine) expression via ALK4/ACVR1B-induced SMAD (zeige SMAD1 Proteine) signaling in trophoblast cells; elevated SNAIL (zeige SNAI1 Proteine) contributes to up-regulation of MMP2 (zeige MMP2 Proteine) expression which plays key role in promoting trophoblast cell invasion.

  7. ACVR1B functions as a positive regulator of monocyte/macrophage differentiation. ACVR1B knockdown promoted THP-1 proliferation by increasing Rb phosphorylation. Down-regulation reduced p-Smad2 (zeige SMAD2 Proteine)/3 and C/EBPalpha (zeige CEBPA Proteine), inhibiting monocyte/macrophage differentiation.

  8. The deletion of the ACVR1B gene may mediate an aggressive cancer phenotype in pancreatic cancer.

  9. Findings define a regulatory role of miR (zeige MLXIP Proteine)-98 in tumor angiogenesis and invasion through repressed ALK4 and MMP11 (zeige MMP11 Proteine) expression.

  10. ActRIBCA signaling can promote cell migration in prostate cancer cells via a network of signaling molecules that work together to trigger the process of EMT (zeige ITK Proteine), and thereby aid in the aggressiveness and progression of prostate cancers.

Activin A Receptor Type IB (ACVR1B) Protein Überblick

Protein Überblick

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit ACVR1B

  • activin A receptor type 1B (ACVR1B)
  • activin A receptor type 1B (acvr1b)
  • Activin receptor type-1B (acv1b)
  • activin A receptor, type IB (ACVR1B)
  • activin A receptor, type 1B (Acvr1b)
  • activin A receptor type 1B (Acvr1b)
  • activin A receptor type 1Ba (acvr1ba)
  • 6820432J04 Protein
  • ActR-IB Protein
  • ACTRIB Protein
  • ACVR1B Protein
  • ACVRLK4 Protein
  • alk-4 Protein
  • ALK4 Protein
  • axis Protein
  • DKFZp469A1614 Protein
  • Skr2 Protein
  • taram-a Protein
  • tarama Protein
  • wu:fb75f01 Protein
  • xalk4 Protein

Bezeichner auf Proteinebene für ACVR1B

activin A receptor, type IB , activin A receptor, type 1B , activin type IB receptor , activin receptor type-1B-like , Activin receptor type-1B , activin receptor IB , ALK-4 , activin receptor type IB , activin receptor type-1B , activin receptor-like kinase 4 , serine/threonine-protein kinase receptor R2 , activin A receptor, type II-like kinase 4 , ACTR-IB , Serine/threonine-protein kinase receptor R2

GENE ID SPEZIES
100062619 Equus caballus
451911 Pan troglodytes
733849 Xenopus (Silurana) tropicalis
768878 Gallus gallus
100391614 Callithrix jacchus
100482103 Ailuropoda melanoleuca
100195539 Salmo salar
443254 Ovis aries
100173725 Pongo abelii
11479 Mus musculus
91 Homo sapiens
29381 Rattus norvegicus
30183 Danio rerio
486537 Canis lupus familiaris
100152462 Sus scrofa
539315 Bos taurus
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