anti-Abhydrolase Domain Containing 5 (ABHD5) Antikörper

The protein encoded by ABHD5 belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. Zusätzlich bieten wir Ihnen ABHD5 Proteine (9) und ABHD5 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABHD5 51099 Q8WTS1
ABHD5 67469 Q9DBL9
ABHD5 316122 Q6QA69
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Top anti-ABHD5 Antikörper auf antikoerper-online.de

Showing 10 out of 77 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB ABIN190850 (1µg/ml) staining of A431 cell line lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-ABHD5 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert SimWes, WB Western Blot: Abhd5 Antibody [ABIN2583726] - Western Blot on Abhd5 overexpression lysates (NBL1-07199). Western Blot: Abhd5 Antibody [ABIN2583726] - Western Blot on MCF7 cell lysates. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
Details
Rind (Kuh) Ziege Unkonjugiert ICC, IF, ELISA, WB Western Blot: ABHD5 Antibody [ABIN252915] - ABIN252915 (1µg/ml) staining of A431 cell line lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: Abhd5 Antibody [ABIN2529150] - Analysis of CGI58 in NIH3T3 lysate (35ug protein in RIPA buffer) using this antibody at 0.2 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Maus Unkonjugiert WB ABHD5 monoclonal antibody (M02), clone 4B12 Western Blot analysis of ABHD5 expression in A-431. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Maus Unkonjugiert WB Western Blot analysis of ABHD5 expression in transfected 293T cell line by ABHD5 monoclonal antibody (M01), clone 1F3. Lane 1: ABHD5 transfected lysate(39 KDa). Lane 2: Non-transfected lysate. Immunoperoxidase of monoclonal antibody to ABHD5 on formalin-fixed paraffin-embedded human small Intestine (antibody concentration 3 µg/mL). 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB   100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Maus Unkonjugiert ELISA, WB ABHD5 monoclonal antibody (M02), clone 4B12 Western Blot analysis of ABHD5 expression in A-431 . Detection limit for recombinant GST tagged ABHD5 is 0.3 ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details

ABHD5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus) ,
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Am meisten referenzierte anti-ABHD5 Antikörper

  1. Human Polyclonal ABHD5 Primary Antibody für SimWes, WB - ABIN258372 : Yamaguchi, Omatsu, Matsushita, Osumi: CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome. in The Journal of biological chemistry 2004 (PubMed)
    Show all 21 Pubmed References

  2. Human Monoclonal ABHD5 Primary Antibody für IHC (p), ELISA - ABIN565526 : Kinney, Qiao, Levaugh, Shao: B56alpha/protein phosphatase 2A inhibits adipose lipolysis in high-fat diet-induced obese mice. in Endocrinology 2010 (PubMed)
    Show all 11 Pubmed References

  3. Human Monoclonal ABHD5 Primary Antibody für ELISA, WB - ABIN565527 : Watt, van Denderen, Castelli, Bruce, Hoy, Kraegen, Macaulay, Kemp: Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness. in Molecular endocrinology (Baltimore, Md.) 2008 (PubMed)
    Show all 3 Pubmed References

  4. Polyclonal ABHD5 Primary Antibody für WB - ABIN540799 : Subramanian, Rothenberg, Gomez, Cohen, Garcia, Bhattacharyya, Shapiro, Dolios, Wang, Lisanti, Brasaemle: Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes. in The Journal of biological chemistry 2004 (PubMed)
    Show all 3 Pubmed References

  5. Cow (Bovine) Polyclonal ABHD5 Primary Antibody für ICC, IF - ABIN252915 : Sitnick, Basantani, Cai, Schoiswohl, Yazbeck, Distefano, Ritov, DeLany, Schreiber, Stolz, Gardner, Kienesberger, Pulinilkunnil, Zechner, Goodpaster, Coen, Kershaw: Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. in Diabetes 2013 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal ABHD5 Primary Antibody für ELISA, WB - ABIN190850 : Lass, Zimmermann, Haemmerle, Riederer, Schoiswohl, Schweiger, Kienesberger, Strauss, Gorkiewicz, Zechner: Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. in Cell metabolism 2006 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen ABHD5 Interaktionspartner

Human Abhydrolase Domain Containing 5 (ABHD5) Interaktionspartner

  1. These results indicate that HCV taps (zeige ASPRV1 Antikörper) into the lipid droplet triglyceride reservoir usurping ABHD5 lipase (zeige LIPG Antikörper) cofactor function

  2. Case Report: novel ABHD5 mutation, c.838C > T (p.Arg280*), in trans with p.Arg234* in a Chinese patient with very mild Dorfman-Chanarin syndrome.

  3. Authors show that rat ATGL (zeige PNPLA2 Antikörper), coactivated by rat CGI-58, efficiently hydrolyzes triglycerides and retinyl ester.

  4. novel ABHD5 truncating variant in a twenty nine month old female child, who presented with icthyosiform erythroderma.

  5. simultaneous tryptophan alanine permutations in both arms abolish localization and activity of CGI-58 as opposed to tryptophan substitutions that occur in only one arm.

  6. this study presents clinical and molecular data of four affected relatives with Chanarin-Dorfman syndrome homozygous for a N209X mutation in ABHD5, and provides a short review by comparing patients with N209X homozygous mutations to patients with other ABHD5 mutations.

  7. PLIN5 (zeige PLIN5 Antikörper) was significantly colocated with ATGL (zeige PNPLA2 Antikörper), mitochondria and CGI-58, indicating a close association between the key lipolytic effectors in resting skeletal muscle.

  8. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin (zeige PLIN1 Antikörper) 1A-coated lipid droplets

  9. Abhd5 expression falls substantially and correlates negatively with malignant features in human colorectal cancer.

  10. Findings indicate a molecular mechanisms by which lysophosphatidic acid acyltransferase (zeige MBOAT2 Antikörper) CGI-58 regulates lipid homeostasis.

Mouse (Murine) Abhydrolase Domain Containing 5 (ABHD5) Interaktionspartner

  1. omega-O-AcylCer and CLE (zeige C14orf166 Antikörper) formation critically depend on CGI-58 expression in differentiated keratinocytes.

  2. These results demonstrate that macrophage CGI-58 enhances PPAR-gamma (zeige PPARG Antikörper) signaling and thus suppresses inflammatory responsiveness and mitochondrial dysfunction in macrophages.

  3. Here, we identify synthetic ligands that release ABHD5 from PLIN1 (zeige PLIN1 Antikörper) or PLIN5 (zeige PLIN5 Antikörper) without PKA activation and rapidly activate adipocyte and muscle lipolysis.

  4. we identify adipocyte-type fatty acid-binding protein (A-Fabp (zeige FABP4 Antikörper)) and other members of the fatty acid-binding protein (Fabp (zeige FABP Antikörper)) family as interaction partners of Cgi-58.

  5. Data (including data from studies in atherosclerotic knockout mice) suggest CGI58-deficient macrophages store-up triglyceride-rich droplets and have reduced phagocytic capacity, comparable to Atgl- (adipose triglyceride lipase (zeige PNPLA2 Antikörper)-)deficient macrophages.

  6. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin (zeige PLIN1 Antikörper) 1A-coated lipid droplets

  7. Muscle CGI-58 deficiency causes cardiac dysfunction and fat deposition in oxidative muscles but induces a series of favorable metabolic changes in mice fed a high-fat diet.

  8. intestinal CGI-58 is required for efficient postprandial lipoprotein-TG secretion and for maintaining hepatic and plasma lipid homeostasis.

  9. CGI-58 transgenic/ApoE (zeige APOE Antikörper)-/- mice exhibited an anti-atherosclerosis phenotype compared with wild type (WT) controls (CGI-58 WT/ApoE (zeige APOE Antikörper)-/-), illustrated by less plaque area in aortic roots.

  10. The anti-lipolytic activity of the HCV core protein alters ATGL (zeige PNPLA2 Antikörper) binding to CGI-58 and enhances the association of both proteins with lipid droplets.

Pig (Porcine) Abhydrolase Domain Containing 5 (ABHD5) Interaktionspartner

  1. These findings suggest that CGI-58 may be a new target for enhancing the quality of pork products as well as offering the potential of CGI-58 for human obesity treatment.

ABHD5 Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.

Genbezeichner und Symbole assoziert mit ABHD5

  • abhydrolase domain containing 5 (ABHD5) Antikörper
  • abhydrolase domain containing 5 (abhd5) Antikörper
  • abhydrolase domain containing 5a (abhd5a) Antikörper
  • abhydrolase domain containing 5 (LOC100229229) Antikörper
  • abhydrolase domain containing 5 (LOC100350162) Antikörper
  • abhydrolase domain containing 5 (Abhd5) Antikörper
  • 1300003D03Rik Antikörper
  • 2010002J10Rik Antikörper
  • abhd5 Antikörper
  • CDS Antikörper
  • CGI-58 Antikörper
  • CGI58 Antikörper
  • IECN2 Antikörper
  • IECN5 Antikörper
  • NCIE2 Antikörper

Bezeichner auf Proteinebene für ABHD5

abhydrolase domain containing 5 , CGI58 protein , 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 , abhydrolase domain-containing protein 5 , lipid droplet-binding protein CGI-58 , alpha/beta hydrolase domain-containing 5 , lipid droplet binding protein , Abhydrolase domain-containing protein 5

GENE ID SPEZIES
460303 Pan troglodytes
549643 Xenopus (Silurana) tropicalis
566493 Danio rerio
100066775 Equus caballus
100229229 Taeniopygia guttata
100350162 Oryctolagus cuniculus
100125355 Ovis aries
51099 Homo sapiens
67469 Mus musculus
485570 Canis lupus familiaris
497624 Sus scrofa
535588 Bos taurus
316122 Rattus norvegicus
446400 Xenopus laevis
420673 Gallus gallus
100174407 Pongo abelii
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