anti-ATR Interacting Protein (ATRIP) Antikörper

ATRIP encodes an essential component of the DNA damage checkpoint. Zusätzlich bieten wir Ihnen ATRIP Kits (7) und ATRIP Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ATRIP 84126 Q8WXE1
ATRIP 235610 Q8BMG1
ATRIP 301014  
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Top anti-ATRIP Antikörper auf antikoerper-online.de

Showing 10 out of 124 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from 293 cells treated with UV 15', using ATRIP (Phospho-Ser224) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using ATRIP (Phospho-Ser224) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using ATRIP (Phospho-Ser68) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IC, FACS, IF, IHC, WB Immunofluorescent analysis of ATRIP staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of ATRIP staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using ATRIP (Ab-68/72) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ATRIP (Ab-68/72) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IP, WB Immunoprecipitation: ATRIP Antibody [ABIN151823] - Whole cell lysate from HeLa and 293-T cells. ATRIP was also IPed using a control antibody generated to recombinant human ATRIP. IPed ATRIP was detected using the antibody to the recombinant protein. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using ATRIP Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Maus Unkonjugiert IF, WB Anti-ATRIP mouse monoclonal antibody (ABIN2455756) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ATRIP (RC223562). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATRIP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ATRIP. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$423.50
Details
Human Maus Unkonjugiert FACS, IF, WB HEK293T cells transfected with either RC223562 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-ATRIP antibody (ABIN2455758), and then analyzed by flow cytometry. Anti-ATRIP mouse monoclonal antibody (ABIN2455758) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ATRIP (RC223562). 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$423.50
Details
Human Maus Unkonjugiert WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATRIP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ATRIP. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$423.50
Details

ATRIP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ATRIP Antikörper

  1. Human Polyclonal ATRIP Primary Antibody für IP, WB - ABIN151823 : Choi, Lindsey-Boltz, Sancar: Reconstitution of a human ATR-mediated checkpoint response to damaged DNA. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

Weitere Antikörper gegen ATRIP Interaktionspartner

Xenopus laevis ATR Interacting Protein (ATRIP) Interaktionspartner

  1. ATRIP must associate with ATR (zeige ATR Antikörper) in order for ATR (zeige ATR Antikörper) to carry out the phosphorylation of Chk1 (zeige CHEK1 Antikörper) effectively

  2. Data show that recombinant TopBP1 (zeige TOPBP1 Antikörper) induces a large increase in the kinase activity of both Xenopus and human ATR (zeige ATR Antikörper)-ATRIP.

Human ATR Interacting Protein (ATRIP) Interaktionspartner

  1. ATRIP deacetylation by SIRT2 promotes ATR-ATRIP binding to replication protein A-single-stranded DNA to drive ATR activation and thus facilitate recovery from replication stress.

  2. ATRIP SUMOylation promotes ATR activation by providing a unique type of protein glue that boosts multiple protein interactions along the ATR pathway

  3. Data on crystal structure of BRCA1 binding with phosphopeptides suggest that C-terminal domain of BRCA1 interacts with ATRIP and BAAT1 (zeige C7orf27 Antikörper) with preferences for specific side chains; in ATRIP, phospho-Ser239 and Phe242 are the main interacting residues.

  4. Data indicate that ATRIP is a direct target gene of HIF-1, and the increased ATRIP then activates the ATR signaling pathway under hypoxia.

  5. our analysis exposes an overlapping clinical manifestation between the disorders but allows an expanded spectrum of clinical features for ATR (zeige ANTXR1 Antikörper)-ATRIP Seckel Syndrome to be defined

  6. as an ATR (zeige ANTXR1 Antikörper)-associated kinase, Nek1 (zeige NEK1 Antikörper) enhances the stability and activity of ATR (zeige ANTXR1 Antikörper)-ATRIP before DNA damage, priming ATR (zeige ANTXR1 Antikörper)-ATRIP for a robust DNA damage response

  7. ATRIP may function outside the context of the canonical ATR damage signaling pathway during HSV-1 infection to participate in the viral life cycle.

  8. data suggest that RPA (zeige RPA1 Antikörper)-coated ssDNA is the critical structure at sites of DNA damage that recruits the ATR (zeige ANTXR1 Antikörper)-ATRIP complex and facilitates its recognition of substrates for phosphorylation and the initiation of checkpoint signaling

  9. there are at least two in vitro ATR-ATRIP DNA binding complexes, one which binds DNA with high affinity in an RPA-dependent manner and a second, which binds DNA with lower affinity in an RPA-independent manner

  10. Collectively, our results suggest that the ATR (zeige ANTXR1 Antikörper)-mediated phosphorylation of ATRIP at Ser (zeige SIGLEC1 Antikörper)-68 and -72 is dispensable for the initial response to DNA damage.

ATRIP Antigen-Profil

Protein Überblick

This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit ATRIP

  • ATR interacting protein (ATRIP) Antikörper
  • ATR interacting protein S homeolog (atrip.S) Antikörper
  • ATR interacting protein (atrip) Antikörper
  • mutagen-sensitive 304 (mus304) Antikörper
  • RAD26 protein (rad26) Antikörper
  • ATRIP, ATR checkpoint kinase regulatory subunit Rad26 (rad26) Antikörper
  • ATR interacting protein (Atrip) Antikörper
  • 6620401K05Rik Antikörper
  • anon-WO0140519.82 Antikörper
  • atrip Antikörper
  • CG7347 Antikörper
  • Dmel\\CG7347 Antikörper
  • mus(3)304 Antikörper
  • mus-304 Antikörper
  • Mus304 Antikörper
  • si:dkey-42i9.5 Antikörper
  • trex1 Antikörper
  • Xatrip Antikörper

Bezeichner auf Proteinebene für ATRIP

ATR-interacting protein , three prime repair exonuclease 1 , ATR interacting protein , ATR-interacting protein-like , CG7347-PA , mus304-PA , mutagen sensitive 304 , ATRIP , ATM and Rad3-related-interacting protein , ATM and Rad3 related interacting protein

GENE ID SPEZIES
415949 Gallus gallus
496388 Xenopus laevis
558534 Danio rerio
742205 Pan troglodytes
100063799 Equus caballus
100101245 Xenopus (Silurana) tropicalis
100355293 Oryctolagus cuniculus
100411124 Callithrix jacchus
100453171 Pongo abelii
40003 Drosophila melanogaster
443563 Xenopus laevis
2543289 Schizosaccharomyces pombe 972h-
100023426 Monodelphis domestica
100476250 Ailuropoda melanoleuca
100590808 Nomascus leucogenys
84126 Homo sapiens
235610 Mus musculus
301014 Rattus norvegicus
608504 Canis lupus familiaris
100523399 Sus scrofa
100125287 Bos taurus
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