ATPase, Class I, Type 8B, Member 1 (ATP8B1) ELISA Kits

ATP8B1 encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. Zusätzlich bieten wir Ihnen ATP8B1 Proteine (9) und ATP8B1 Antikörper (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Ratte ATP8B1 ATP8B1 291555  
Anti-Human ATP8B1 ATP8B1 5205 O43520
Anti-Maus ATP8B1 ATP8B1 54670 Q148W0
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Weitere ELISA Kits für ATP8B1 Interaktionspartner

Human ATPase, Class I, Type 8B, Member 1 (ATP8B1) Interaktionspartner

  1. Patients with a confirmed ABCB11 (zeige ABCB11 ELISA Kits) or tight junction protein 2 (zeige TJP2 ELISA Kits) gene mutation (n = 7) had a minimally detectable THBA proportion (0.23-2.99% of total BAs). Three patients with an ATP8B1 mutation had an elevated THBA proportion (7.51-37.26%).

  2. the first characterisation at the protein level of six ABCB4 (zeige ABCB4 ELISA Kits) variants (D243A, K435T, G535D, I490T, R545C, and S978P) previously found in patients with inflammatory liver diseases or liver cancer, is reported.

  3. The lipid flippases, ATP8B1 and ATP11A (zeige ATP11A ELISA Kits) are novel elements of the innate immune response that are essential to attenuate the inflammatory response, possibly by mediating endotoxin-induced internalization of TLR4 (zeige TLR4 ELISA Kits).

  4. ATP8B1 is important for proper CFTR (zeige CFTR ELISA Kits) expression and function.

  5. GGT levels in patients with ATP8B1 or ABCB11 deficiency varied with age. The peak GGT value was <70U/L in the 2nd~6th month of life, <60U/L in the 7th~12th month and <50U/L beyond one year

  6. As hypothyroidism can be another extrahepatic feature of ATP8B1 deficiency, thyroid function should be monitored in these patients.

  7. the predominant P4 ATPases in pure pancreatic beta cells and human and rat pancreatic islets were ATP8B1, ATP8B2, and ATP9A. ATP8B1 and CDC50A were highly concentrated in ISG

  8. insufficient activity of Atp8b1/FIC1 increases susceptibility to bacterial pneumonia.

  9. We systematically characterized the molecular consequences of 14 ATP8B1 mutations at exon-intron boundaries associated with ATP8B1 deficiency and found that the majority resulted in total exon skipping

  10. Data indicate that the lipid flippase (ATP8B1)-transmembrane protein 30A (CDC50A) heterodimer is essential for the apical localization of sodium-dependent bile acid transporter (SLC10A2/ASBT (zeige SLC10A2 ELISA Kits)) in Caco-2 cells.

Mouse (Murine) ATPase, Class I, Type 8B, Member 1 (ATP8B1) Interaktionspartner

  1. ATP8B1 is important for proper CFTR (zeige CFTR ELISA Kits) expression and function.

  2. to become apically clustered, Cdc42 (zeige CDC42 ELISA Kits) requires the interaction between its polybasic region and negatively charged membrane lipids provided by ATP8B1.

  3. The authors show that two of these transporters, ABCB11 (zeige ABCB11 ELISA Kits) and ATP8B1, are functional targets of miR (zeige MLXIP ELISA Kits)-33, a micro-RNA that is expressed from within an intron of SREBP-2 (zeige SREBF2 ELISA Kits).

  4. Flippase ATP8B1 and the floppase ABCB4 (zeige ABCB4 ELISA Kits) have complementary functions in maintaining canalicular membrane integrity.

  5. results unveil a new paradigm whereby Atp8b1 is a cardiolipin importer whose capacity to remove cardiolipin from lung fluid is exceeded during inflammation or when Atp8b1 is defective

  6. Data show that ATP8B1-deficient pups of B6 background gained less weight.

  7. Fic1 is expressed in a tissue-specific and developmentally regulated fashion at the apical membranes of epithelial cells

  8. Atp8b1 deficiency causes loss of canalicular phospholipid membrane asymmetry that in turn renders the canalicular membrane less resistant toward hydrophobic bile salts.

  9. The accumulation of bile salt (BS) in plasma of Atp8b1(G308V/G308V) mice during BS feeding is not caused by increased intestinal BS absorption.

  10. Increased biliary cholesterol excretion in Atp8b1-deficient mice is independent of Abcg5 (zeige ABCG5 ELISA Kits)/8 activity.

ATP8B1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis.

Genbezeichner und Symbole assoziert mit ATP8B1

  • ATPase, aminophospholipid transporter, class I, type 8B, member 1 (Atp8b1) Antikörper
  • ATPase, aminophospholipid transporter, class I, type 8B, member 1 (ATP8B1) Antikörper
  • ATPase, aminophospholipid transporter, class I, type 8B, member 1 (atp8b1) Antikörper
  • ATPase, class I, type 8B, member 1 (Atp8b1) Antikörper
  • AI451886 Antikörper
  • ATPIC Antikörper
  • BRIC Antikörper
  • FIC1 Antikörper
  • Ic Antikörper
  • ICP1 Antikörper
  • MGC69272 Antikörper
  • PFIC Antikörper
  • PFIC1 Antikörper

Bezeichner auf Proteinebene für ATP8B1

ATPase, Class I, type 8B, member 1 , probable phospholipid-transporting ATPase IC , ATPase, aminophospholipid transporter, class I, type 8B, member 1 , ATPase, class I, type 8B, member 1 , ATPase, Class 1, type 8B, member 1 , E1-E2 ATPase , familial intrahepatic cholestasis type 1 , phospholipid-transporting ATPase IC , ATPase 8B1, p type , ATPase B1, class I , aminophospholipid translocase , familial intrahepatic cholestasis type I

GENE ID SPEZIES
291555 Rattus norvegicus
455439 Pan troglodytes
541187 Bos taurus
594952 Xenopus (Silurana) tropicalis
733158 Xenopus laevis
100054112 Equus caballus
100126733 Papio anubis
5205 Homo sapiens
54670 Mus musculus
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