anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) Antikörper

The protein encoded by ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ABCC3 Kits (20) und ABCC3 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCC3 8714 O15438
ABCC3 76408 B2RX12
ABCC3 140668 O88563
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Top anti-ABCC3 Antikörper auf antikoerper-online.de

Showing 10 out of 80 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB WB Suggested Anti-ABCC3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB ABCC3 Antibody (Center) (ABIN654103) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB ABCC3 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. ABCC3 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCC3 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Maus Unkonjugiert IHC (fro), IF, WB   1 mL Anmelden zum Anzeigen 7 bis 9 Tage
462,00 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western Blot (WB) analysis of specific cells using MRP3 Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert IP, WB Western blot analysis of MRP3 expression in HepG2 (A), MCF7 (B), MDAMB435 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Maus Unkonjugiert IHC (fro), IF, WB   500 μL Anmelden zum Anzeigen 15 bis 21 Tage
541,97 €
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Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cells, using ABCC3 antibody. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details

ABCC3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ABCC3 Antikörper

  1. Human Polyclonal ABCC3 Primary Antibody für EIA, IHC (p) - ABIN950200 : Hoffman, Urbatsch, Vogel: Nucleotide binding to the human multidrug resistance protein 3, MRP3. in The protein journal 2010 (PubMed)
    Zeige alle 5 Referenzen für 950200

  2. Dog (Canine) Polyclonal ABCC3 Primary Antibody für WB - ABIN2781505 : Müller, Asher, Heled, Cohen, Risch, Rund: Polymorphisms in transporter and phase II metabolism genes as potential modifiers of the predisposition to and treatment outcome of de novo acute myeloid leukemia in Israeli ethnic groups. in Leukemia research 2008 (PubMed)
    Zeige alle 2 Referenzen für 2781505

  3. Human Monoclonal ABCC3 Primary Antibody für IHC (fro), IF - ABIN1105171 : Kool, de Haas, Scheffer, Scheper, van Eijk, Juijn, Baas, Borst: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. in Cancer research 1997 (PubMed)
    Zeige alle 2 Referenzen für 1105171

  4. Human Polyclonal ABCC3 Primary Antibody für FACS, IHC (p) - ABIN654103 : Moyer, Sun, Batzler, Li, Schaid, Yang, Weinshilboum: Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 (PubMed)

Weitere Antikörper gegen ABCC3 Interaktionspartner

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) Interaktionspartner

  1. miR (zeige MLXIP Antikörper)-148a-siRNA and rifampin inhibited estradiol upregulation of MRP3 expression. miR (zeige MLXIP Antikörper)-148a may be involved in the estrogen induction in intrahepatic cholestasis of pregnancy via PXR (zeige NR1I2 Antikörper) signaling. MRP3 may be involved.

  2. ABCC3 genetic variants are associated with postoperative morphine-induced respiratory depression and morphine pharmacokinetics in children.

  3. PXR (zeige NR1I2 Antikörper) is a potential biomarker for predicting outcome and activates MRP3 transcription by directly binding to its promoter resulting in an increased L-OHP efflux capacity, and resistance to L-OHP or platinum drugs in CRC (zeige CALR Antikörper).

  4. This study highlights the importance of ABCC3 transporters in drug resistance to chemotherapy in the context of breast cancer.

  5. Wnt (zeige WNT2 Antikörper) signaling regulates ABCC3 expression in colon cancer cells, with the ABCC3 locus being a target of the transcription factors TCF7L2 (zeige TCF7L2 Antikörper) and beta-catenin (zeige CTNNB1 Antikörper).

  6. ABCC3 is an important oncoprotein involved in glycolysis and drug resistance

  7. This report is the first to describe liver overexpression of Abcc3 during the cancer initiation, promotion, and progression periods in rat hepatocarcinogenesis model and in human hepatocellular carcinoma

  8. High MRP expression is associated with sorafenib resistance in hepatocellular carcinoma.

  9. ABCC3 rs4148416 polymorphism was significantly associated with poor osteosarcoma response.

  10. Data suggest that hepatic expression of MRP3 is up-regulated and canalicular localization of MRP2 (zeige ABCC2 Antikörper) is altered in pediatric patients with advanced nonalcoholic steatohepatitis; these alterations may be involved in changes observed in drug metabolism.

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) Interaktionspartner

  1. data show that this transporter activity is involved in ABCC3-induced senescence, demonstrating that this protein has a complex role in cancer, since its loss of function may promote escape from OIS and tumor formation

  2. Transport of cefadroxil by ABCC3 and ABCC4 (zeige ABCC4 Antikörper) was saturable with K(m) values of 2.5 +/- 0.7 and 0.25 +/- 0.07 mM, respectively.

  3. role of the bile acid membrane transporter Mrp3 (Abcc3), which is expressed in the liver and gut (zeige GUSB Antikörper), in the hepatic growth response elicited by bile acids and in liver regeneration after partial hepatectomy

  4. Both Abcc2 (zeige ABCC2 Antikörper) and Abcc3 significantly influenced the PK properties of MTX (zeige MTX1 Antikörper).

  5. InsP(3)R2-mediated Ca(2 (zeige CA2 Antikörper)+) signals enhance organic anion secretion into bile by targeting Mrp2 (zeige ABCC2 Antikörper) to the canalicular membrane.

  6. Data show that Abcc2 (zeige ABCC2 Antikörper), Abcc3, and Abcg2 (zeige ABCG2 Antikörper) together mediate the rapid elimination of MTX (zeige MTX1 Antikörper) and 7OH-MTX (zeige MTX1 Antikörper).

  7. These results suggest that Mrp3 plays major roles in the efflux transport of various glucuronide conjugates from the enterocytes to the portal blood in the small intestine together with unknown transporter(s)

  8. induction of Mrp3 plays a significant role in hepatocyte protection during obstructive cholestasis

  9. VDR (zeige CYP27B1 Antikörper) has a role in the protection of colon cells from bile acid toxicity through regulation of the Mrp3 expression

  10. Mrp3 does not have a major role in bile salt physiology, but is involved in the transport of glucuronidated compounds, which could include glucuronidated bile salts in humans

ABCC3 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined\; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.

Genbezeichner und Symbole assoziert mit ABCC3

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (ABCC3) Antikörper
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (Abcc3) Antikörper
  • ATP-binding cassette, subfamily C (CFTR/MRP), member 3 (Abcc3) Antikörper
  • 1700019L09Rik Antikörper
  • ABC31 Antikörper
  • cMOAT2 Antikörper
  • EST90757 Antikörper
  • Mlp2 Antikörper
  • MOAT-D Antikörper
  • Mrp3 Antikörper

Bezeichner auf Proteinebene für ABCC3

ATP-binding cassette sub-family C member 3 , canalicular multispecific organic anion transporter 2 , canicular multispecific organic anion transporter , multi-specific organic anion transporter D , multidrug resistance associated protein , multidrug resistance-associated protein 3 , ATP-binding cassette protein C3 , ATP-binding cassette transporter , transporter , ATP-binding cassette, sub-family C (CFTR/MRP), member 3 , MLP-2 , MRP-like protein 2 , multidrug resistance protein 3 , organic anion transporter

GENE ID SPEZIES
8714 Homo sapiens
76408 Mus musculus
140668 Rattus norvegicus
Ausgewählte Anbieter für anti-ABCC3 (ABCC3) Antikörper
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