anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) Antikörper

The protein encoded by ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ABCC1 Kits (29) und ABCC1 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCC1 4363 P33527
ABCC1 17250 O35379
ABCC1 24565 Q8CG09
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Top anti-ABCC1 Antikörper auf antikoerper-online.de

Showing 10 out of 83 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert FACS, WB Western blot analysis of ABCC1 antibody (C-term) (ABIN390525) in Ramos cell line lysates (35 µg/lane). ABCC1 (arrow) was detected using the purified polyclonal antibody. Flow cytometric analysis of NCI-H292 cells using ABCC1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-MRP1 antibody, Western blotting Lane 1: JURKAT Cell Lysate Lane 2: CEM Cell Lysate Lane 3: A549 Cell Lysate Anti-MRP1 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Ziege Unkonjugiert ELISA, WB EB08734 (0.05µg/ml) staining of A549 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Western blot analysis of MRP expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Ratte Unkonjugiert IHC (fro), IF, IHC (p), WB   1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
Details
Human Maus Unkonjugiert IHC (fro), IF, IHC (p), WB   1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
Details
Human Maus Fluorescein FACS Detection of MRP1 in H69AR Human Cell Line by Flow Cytometry. H69AR human small cell lung cancer cell line was stained with Mouse Anti-Human MRP1 Fluorescein-conjugated Monoclonal Antibody. Detection of MRP1 in H69AR Human Cell Line by Flow Cytometry. H69AR human small cell lung cancer cell line was stained with Mouse Anti-Human MRP1 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$252.00
Details
Human Maus PE FACS Detection of MRP1 in H69AR Human Cell Line by Flow Cytometry. H69AR human small cell lung cancer cell line was stained with Mouse Anti-Human MRP1 PE-conjugated Monoclonal Antibody. Detection of MRP1 in H69AR Human Cell Line by Flow Cytometry. H69AR human small cell lung cancer cell line was stained with Mouse Anti-Human MRP1 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$315.00
Details

ABCC1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ABCC1 Antikörper

  1. Human Polyclonal ABCC1 Primary Antibody für IHC (p), WB - ABIN3044230 : Wang, Zhao, Wu, He, Qu, Zhao, Zhao, Li, Wang: Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line. in Asian Pacific journal of cancer prevention : APJCP 2013 (PubMed)
    Show all 2 Pubmed References

  2. Monoclonal ABCC1 Primary Antibody für IF, WB - ABIN534097 : Chen, Yang, Li, Zhang: The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function. in The Journal of biological chemistry 2006 (PubMed)

  3. Human Monoclonal ABCC1 Primary Antibody für FACS - ABIN4898742 : Keshet, Goldstein, Itzhaki, Cesarkas, Shenhav, Yakirevitch, Treves, Schachter, Amariglio, Rechavi: MDR1 expression identifies human melanoma stem cells. in Biochemical and biophysical research communications 2008 (PubMed)

  4. Human Monoclonal ABCC1 Primary Antibody für FACS - ABIN4898743 : Takahashi, Shibata, Oba, Ishikawa, Yoshikawa, Tatsunami, Takahashi, Tampo: Multidrug-resistance-associated protein plays a protective role in menadione-induced oxidative stress in endothelial cells. in Life sciences 2009 (PubMed)

  5. Human Monoclonal ABCC1 Primary Antibody für CyTOF, FACS - ABIN4900819 : Fiskus, Rao, Fernandez, Herger, Yang, Chen, Kolhe, Mandawat, Wang, Joshi, Eaton, Lee, Atadja, Peiper, Bhalla: Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells. in Blood 2008 (PubMed)

Weitere Antikörper gegen ABCC1 Interaktionspartner

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) Interaktionspartner

  1. These results show that multidrug resistant leukemia cell microparticle regulation of ABCC1 in recipient cells is governed by the transfer of both miR (zeige MLXIP Antikörper)-326 and ABCB1 (zeige ABCB1 Antikörper) from donor cells

  2. Higher expression of ABCG2 (zeige ABCG2 Antikörper) and MRP1 (zeige MDM4 Antikörper), and lower expression of CK19 (zeige KRT19 Antikörper) in papillary thyroid carcinomas with a solid component were associated with higher tumor recurrence rate and shorter disease-free survival.

  3. Visfatin (zeige NAMPT Antikörper) increases the nuclear translocation of Akt (zeige AKT1 Antikörper) and its binding with ABCC1. These data showed that visfatin (zeige NAMPT Antikörper) can decrease doxorubicin sensitivity of Non-small-cell lung cancer cells via activation of Akt (zeige AKT1 Antikörper)/MRP1 (zeige MDM4 Antikörper).

  4. Studied hedgehog (zeige SHH Antikörper) signaling effect thru ATP-binding cassette (ABC (zeige ABCB6 Antikörper)) transporters in hepatoma drug sensitivity. Results suggest Hedgehog (zeige SHH Antikörper) signaling transcription factor Gli-2 (zeige GLI2 Antikörper) to be the primary regulator for drug sensitivity of hepatoma through the ABCC1 transporter.

  5. This study demonstrated that mitochondrial MRP-1 (zeige MDM4 Antikörper) is expressed in the outer mitochondrial membrane and is a client protein of HSP90beta (zeige HSP90AB1 Antikörper).

  6. High ABCC1 expression is associated with hepatic fibrosis.

  7. This study shows direct binding between MRP1 (zeige MDM4 Antikörper) Linker 1 (L1MRP1) domain and alpha- and beta-tubulin (zeige TUBB Antikörper) subunits, using a scanning peptide approach

  8. In summary, chaetominine strongly reverses drug resistance by interfering with the PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper)/Nrf2 (zeige GABPA Antikörper) signaling, resulting in reduction of MRP1 (zeige MDM4 Antikörper)-mediated drug efflux and induction of Bax (zeige BAX Antikörper)/Bcl-2 (zeige BCL2 Antikörper)-dependent apoptosis in an ADR (zeige AKR1B1 Antikörper)-resistant K562/Adr (zeige AKR1B1 Antikörper) leukemia cell line.

  9. cross-talk between MRP1 (zeige MDM4 Antikörper) glycosylation and phosphorylation occurs.

  10. meta-analysis results strongly suggest that MRP1 (zeige MDM4 Antikörper) is overexpressed in both neurons and astrocytes of intractable epilepsy patients, inhibition of MRP1 (zeige MDM4 Antikörper) may enhance antiepileptic drug efficacy by increasing local drug availability

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) Interaktionspartner

  1. Loss of ABCC1 expression is associated with neonatal hyperbilirubinemia.

  2. Data, including data from studies in knockout mice, suggest that Mrp1 is involved in development of vascular endothelial dysfunction in diabetic angiopathy; Mrp1 appears to be required for oxidative stress in endothelial cells due to hyperglycemia.

  3. Oxidant-enriched Tumorigenic Endothelial Cells (EOMA) cells survive a heavy oxidant burden by rapid efflux of GSSG, which is lethal if trapped within the cell. A hyperactive MRP-1 system for GSSG efflux acts as a critical survival factor for these cells, making it a potential target for EOMA therapeutics.

  4. P-gp, Bcrp, Mrp1 and Mrp4 are differentially expressed at the outer and inner blood retinal barrier, resulting in an altered ability to limit substrate distribution at the retina as compared with the blood brain barrier

  5. Lentivirus-based RNAi stably knocks down the expression of the Mrp1 gene in the established TM4 (zeige TPM4 Antikörper) sertoli cell line.

  6. neprilysin (zeige MME Antikörper) x ABCC1 double-deficient mice present a new model for early effects of amyloid-beta-related mild cognitive impairment that allows investigations without artificial overexpression of inherited Alzheimer's disease genes

  7. Expression of apoA-I (zeige APOA1 Antikörper) or ABCA1 (zeige ABCA1 Antikörper) can reduce steatosis by decreasing lipid storage in hepatocytes through lipid transport and may also reduce endoplasmic reticulum stress, further lessening hepatic steatosis

  8. Loss of Mrp1 coupled with reductions in steroid hormone levels leads to alterations in extrahepatic phase I, phase II and phase III metabolizing enzymes in a tissue-specific manner.

  9. Cd or H(2)O(2) exposure increased the expression of key transport genes, Mrp1 and Mrp2 (zeige ABCC2 Antikörper), in WT cells but not in metallothionein (zeige MT Antikörper)-null cells.

  10. These results identify Mrp1 as the transporter essential for S1P (zeige S1PR1 Antikörper) efflux from the endothelial cells and thus for inside-out S1P (zeige S1PR1 Antikörper) signaling to P-glycoprotein at the blood-brain and blood-spinal cord barriers.

Cow (Bovine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) Interaktionspartner

  1. Using electron cryomicroscopy, authors determined the molecular structures of bovine MRP1 in two conformations: an apo (zeige C9orf3 Antikörper) form at 3.5 A without any added substrate and a complex form at 3.3 A with one of its physiological substrates, leukotriene C4; structures show that by forming a single bipartite binding site, MRP1 can recognize a of substrates with different chemical structures.

  2. P-gp (zeige ABCB4 Antikörper), Bcrp (zeige ABCG2 Antikörper) and Mrp1 are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

ABCC1 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.

Genbezeichner und Symbole assoziert mit ABCC1

  • ATP binding cassette subfamily C member 1 (ABCC1) Antikörper
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1) Antikörper
  • ATP binding cassette subfamily C member 1 (Abcc1) Antikörper
  • ABC29 Antikörper
  • ABCC Antikörper
  • Abcc1a Antikörper
  • Abcc1b Antikörper
  • Avcc1a Antikörper
  • GS-X Antikörper
  • Mdrap Antikörper
  • Mrp Antikörper
  • Mrp1 Antikörper

Bezeichner auf Proteinebene für ABCC1

ATP-binding cassette transporter variant ABCC1delta-ex13 , ATP-binding cassette transporter variant ABCC1delta-ex13&14 , ATP-binding cassette transporter variant ABCC1delta-ex25 , ATP-binding cassette transporter variant ABCC1delta-ex25&26 , LTC4 transporter , leukotriene C(4) transporter , multidrug resistance-associated protein 1 , ATP-binding cassette sub-family C member 1 , multidrug resistance protein 1 , ATP-binding cassette, sub-family C (CFTR/MRP), member 1a , ATP-binding cassette, sub-family C (CFTR/MRP), member 1b , multiple drug resistance-associated protein , ATP-binding cassette sub-family C ( CFTR/MRP) member 1a , ATP-binding cassette, sub-family C (CFTR/MRP), member 1 , ATP-binding cassette superfamily member C1 , ATP-binding cassette transporter sub-family C member 1 , ATP-binding cassette, sub-family C, member 1 , multiple drug resistance protein 1

GENE ID SPEZIES
4363 Homo sapiens
281588 Bos taurus
395416 Gallus gallus
403453 Canis lupus familiaris
17250 Mus musculus
24565 Rattus norvegicus
100734674 Cavia porcellus
733619 Sus scrofa
791240 Equus caballus
100345841 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-ABCC1 (ABCC1) Antikörper
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