anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antikörper

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits (20) und ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antikörper auf antikoerper-online.de

Showing 10 out of 279 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-ABCB1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>NCI-H226 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Anmelden zum Anzeigen 5 bis 7 Tage
157,14 €
Details
Human Kaninchen Unkonjugiert IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Hund Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
391,60 €
Details
Human Maus Unkonjugiert IHC (fro), IF, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
374,00 €
Details
Human Maus Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
494,23 €
Details
Human Maus Unkonjugiert IHC (p), WB Human Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Human Kaninchen Unkonjugiert IHC (p) Anti-ABCB1 / MDR1 antibody  ABIN1048283 IHC staining of human kidney, proximal convoluted tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Hamster Kaninchen Unkonjugiert IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
801,43 €
Details
Human Maus Unkonjugiert FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
319,00 €
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ABCB1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antikörper

  1. Human Monoclonal ABCB1 Primary Antibody für ICC, IHC (fro) - ABIN3043101 : Gao, Liu, Wang, Lin, Zhang: Effects of Lewis Y antigen on the gene expression of multiple drug resistance-associated proteins in human ovarian cancer RMG-I-H cells. in Medical oncology (Northwood, London, England) 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal ABCB1 Primary Antibody für IHC (fro), FACS - ABIN2479419 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal ABCB1 Primary Antibody für FACS - ABIN2479421 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... in Cancer research 1996 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal ABCB1 Primary Antibody für FACS - ABIN2479422 : Koziolek, Riess, Geiger, Thévenod, Hauser: Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients. in Kidney international 2001 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal ABCB1 Primary Antibody für FACS - ABIN2479424 : Park, Lomri, Simeoni, Fruehauf, Mechetner: Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal ABCB1 Primary Antibody für ELISA, WB - ABIN1724927 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. in Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal ABCB1 Primary Antibody für ELISA, WB - ABIN1724923 : Rubi?, Ho?ysz, Barczak, Gryczka, ?aci?ski, Jagielski, Czernikiewicz, Pó?rolniczak, Wojewoda, Perz, Bia?ek, Morze, Kandu?a, Lisiak, Mrozikiewicz, Grodecka-Gazdecka, Rybczy?ska: Study of ABCB1 polymorphism frequency in breast cancer patients from Poland. in Pharmacological reports : PR 2013 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal ABCB1 Primary Antibody für IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. in Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal ABCB1 Primary Antibody für IHC (fro), IHC (p) - ABIN3043967 : Wang, Deng, Lu, Xu, Yan, Ye, Chen et al.: Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 ... in Basic & clinical pharmacology & toxicology 2012 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal ABCB1 Primary Antibody für IHC (p) - ABIN2479425 : Marzolini, Paus, Buclin, Kim: Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance. in Clinical pharmacology and therapeutics 2004 (PubMed)

Weitere Antikörper gegen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Interaktionspartner

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Interaktionspartner

  1. P-gp (zeige ABCB4 Antikörper), Bcrp (zeige ABCG2 Antikörper) and Mrp1 (zeige ABCC1 Antikörper) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Interaktionspartner

  1. our findings demonstrated that MDR1 (zeige TBC1D9 Antikörper) expression is regulated by CDX2 (zeige CDX2 Antikörper) and is related to drug resistance in ovarian mucinous adenocarcinoma.

  2. Compared with the sensitive group, both mdr1 (zeige TBC1D9 Antikörper) mRNA and P-gp (zeige ABCB4 Antikörper) expressions increased in the resistant group

  3. an SNP in ABCB1 (rs2032582: 2677G > T/A) was significantly associated with atorvastatin-induced liver injury (AILI) indicating that the G allele might be a risk factor for AILI in Japanese population

  4. impact of CYP4F2 (zeige CYP4F2 Antikörper), ABCB1, and GGCX (zeige GGCX Antikörper) polymorphisms on bleeding episodes associated with acenocoumarol in Russian patients with atrial fibrillation

  5. Collectively, the data establish a hitherto unknown liaison among MDR1 (zeige TBC1D9 Antikörper), BMI1 (zeige BMI1 Antikörper) and TIP60 (zeige KAT5 Antikörper) and provide mechanistic insights into cisplatin-induced MDR1 (zeige TBC1D9 Antikörper) expression resulting in acquired cross-resistance against paclitaxel, doxorubicin and likely other anticancer drugs.

  6. High ABCB1 expression is associated with hepatocellular carcinoma.

  7. Our data suggest that the C1236T and G2677A/T SNPs in the MDR1 (zeige TBC1D9 Antikörper) gene are associated with Crohn's disease and the C1236T risk allele with a more severe course of disease in Algerian pediatric patients.

  8. ATPase (zeige DNAH8 Antikörper) measurements imply that DCV and Ho are similarly handled by ABCB1, whereas ABCG2 (zeige ABCG2 Antikörper) seems to transport DVC more effectively. In addition, we have developed an image-based high content microscopy screening method for simultaneous in situ measurement of the cellular activity and expression of the ABCG2 (zeige ABCG2 Antikörper) multidrug transporter

  9. These results show that multidrug resistant leukemia cell microparticle regulation of ABCC1 (zeige ABCC1 Antikörper) in recipient cells is governed by the transfer of both miR (zeige MLXIP Antikörper)-326 and ABCB1 from donor cells

  10. he modulatory effect of acacetin-doxorubicin combination on doxorubicin influx and efflux was mediated through downregulation of MDR1 (zeige TBC1D9 Antikörper) treansporter in non-small-cell lung carcinoma (NSCLC) cells.

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Interaktionspartner

  1. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  2. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (zeige ABCB4 Antikörper) ATPase (zeige DNAH8 Antikörper) activity

  3. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  4. Chrysosplenetin inhibited P-gp (zeige ABCB4 Antikörper) activity and reverse the up-regulated P-gp (zeige ABCB4 Antikörper) and MDR1 (zeige ABCB4 Antikörper) levels induced by artemisinin.

  5. Tamsulosin and tolterodine with P-gp (zeige ABCB4 Antikörper) gene expression and activity in an enantiomer-specific way.

  6. Pgp (zeige ABCB4 Antikörper)-coupled ATPase (zeige DNAH8 Antikörper) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  7. Data show that human transgenic mutant huntingtin (zeige HTT Antikörper) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (zeige ABCB4 Antikörper)) which suggests that MDR1 (zeige ABCB4 Antikörper) might be a potential therapeutic target for Huntington's disease.

  8. In vitro and in vivo downregulation of the ATP binding cassette transporter (zeige ABCC3 Antikörper) B1 by the HMG-CoA reductase (zeige HMGCR Antikörper) inhibitor simvastatin

  9. Efficient chemoprotection of CDD (zeige CDA Antikörper) and MDR1 (zeige ABCB4 Antikörper) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (zeige FOXC1 Antikörper)-C and anthracycline application

  10. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (zeige ABCB4 Antikörper) substrates.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antigen-Profil

Protein Überblick

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Genbezeichner und Symbole assoziert mit ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) Antikörper
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) Antikörper
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) Antikörper
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • malic enzyme complex, mitochondrial (Mod2) Antikörper
  • ABC20 Antikörper
  • ABCB1 Antikörper
  • Cd243 Antikörper
  • CLCS Antikörper
  • GP170 Antikörper
  • Mdr Antikörper
  • Mdr-1 Antikörper
  • Mdr1 Antikörper
  • Mdr1a Antikörper
  • Mdr1b Antikörper
  • Mod-2 Antikörper
  • Mod-2r Antikörper
  • Mod-2s Antikörper
  • Mod2-r Antikörper
  • Mod2-s Antikörper
  • p-gp Antikörper
  • PGP1 Antikörper
  • Pgy-1 Antikörper
  • Pgy1 Antikörper
  • xemdr Antikörper

Bezeichner auf Proteinebene für ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPEZIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
Ausgewählte Anbieter für anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antikörper
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