anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antikörper

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antikörper auf antikoerper-online.de

Showing 10 out of 31 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$384.56
Details
Human Maus Unkonjugiert IF, IP, WB   100 μL Anmelden zum Anzeigen 16 Days
$405.08
Details
Human Maus Unkonjugiert IC, FACS, IHC, WB   250 μg Anmelden zum Anzeigen 11 bis 16 Tage
$771.57
Details
Human Ratte Unkonjugiert IC, FACS, IHC, WB   125 μg Anmelden zum Anzeigen 11 bis 16 Tage
$795.14
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Human Maus Unkonjugiert IC, FACS, IHC, WB   125 μg Anmelden zum Anzeigen 11 bis 16 Tage
$807.71
Details
Human Maus Unkonjugiert WB   100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$570.43
Details
Human Maus Unkonjugiert IC, FACS, IP, IHC, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$672.57
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Human Maus Unkonjugiert IC, FACS, IP   1 mL Anmelden zum Anzeigen 11 bis 16 Tage
$707.14
Details
Human Maus Unkonjugiert FACS, IF, IHC, WB   500 μL Anmelden zum Anzeigen 11 bis 16 Tage
$650.57
Details

ABCB1B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antikörper

  1. Human Polyclonal ABCB1B Primary Antibody für FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. in Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Interaktionspartner

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Interaktionspartner

  1. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (zeige ABCB4 Antikörper)--{REVIEW}

  2. Studied ABCB1 (zeige ABCB1 Antikörper) protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1 (zeige ABCB1 Antikörper)-expressing neurons in the left habenula.

  3. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (zeige ABCC6 Antikörper), ABCB1 (zeige ABCB1 Antikörper) and CYP2C8 (zeige CYP2C8 Antikörper) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

  4. The authors found that transient TUBB3 (zeige TUBB3 Antikörper) activation, through ABCB1 (zeige ABCB1 Antikörper), in response to the stimulation of FOXO3a (zeige FOXO3 Antikörper) expression, significantly contributes to the cross-resistance of the paclitaxel-resistant cell population and consequently limits the efficacy of both agents where cancer cells have developed multiple resistance.

  5. MDR1 (zeige TBC1D9 Antikörper) and CYP3A5 (zeige CYP3A5 Antikörper) genetic polymorphisms significantly influence plasma trough levels and therapeutic response of imatinib in patients with chronic myeloid leukemia (zeige BCL11A Antikörper). Patients with GG genotype for CYP3A5 (zeige CYP3A5 Antikörper)-A6986G (P=0.016) and TT genotype for MDR1 (zeige TBC1D9 Antikörper)-C3435T (P=0.013) polymorphisms had significantly higher trough levels of imatinib.

  6. Rescue experiments confirmed the combined role of LUCAT1, miR (zeige MLXIP Antikörper)-200c and ABCB1 (zeige ABCB1 Antikörper) on osteosarcoma proliferation, invasion and methotrexate resistance. Overall, results indicate the vital role of LUCAT1 in the methotrexate resistance regulation through miR (zeige MLXIP Antikörper)-200c/ABCB1 (zeige ABCB1 Antikörper) pathway, providing a novel insight and treatment strategy for osteosarcoma drug resistance.

  7. Mdr1 (zeige TBC1D9 Antikörper) enforces T Cell homeostasis in the presence of intestinal bile acids.

  8. Data show that co-treated with vincristine and XL019, a inhibitor of JAK2 and P-glycoprotein (P-gp), up-regulated expression of p21 and phosphorylated H2A histone family, member X (pH2AX).

  9. Tangeretin could sensitize ABCB1 (zeige ABCB1 Antikörper)-overexpressing cancer cells to chemotherapeutical agents by directly inhibiting ABCB1 (zeige ABCB1 Antikörper) transporter function.

  10. over-functional P-gp (zeige ABCB4 Antikörper) might play an important role in the pathogenesis of ITP (zeige ITPA Antikörper) and induce GCs (zeige GCLC Antikörper) resistance in nonresponsive ITP (zeige ITPA Antikörper) patients. The blockage of P-gp (zeige ABCB4 Antikörper) could be a promising therapeutic approach for GCs (zeige GCLC Antikörper)-resistant patients with ITP (zeige ITPA Antikörper).

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Interaktionspartner

  1. conclusion, MDR1 (zeige ABCB4 Antikörper) and BCRP (zeige ABCG2 Antikörper) are expressed on apical membranes of the rodent placental SynT (zeige STX1A Antikörper)-II layer.

  2. Mdr1 (zeige ABCB4 Antikörper) enforces T Cell homeostasis in the presence of intestinal bile acids.

  3. Loss of ABCB1 (zeige ABCB1 Antikörper) expression is associated with neonatal hyperbilirubinemia.

  4. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (zeige ABCB4 Antikörper) ATPase (zeige DNAH8 Antikörper) activity

  5. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  6. Chrysosplenetin inhibited P-gp (zeige ABCB4 Antikörper) activity and reverse the up-regulated P-gp (zeige ABCB4 Antikörper) and MDR1 (zeige ABCB4 Antikörper) levels induced by artemisinin.

  7. Tamsulosin and tolterodine with P-gp (zeige ABCB4 Antikörper) gene expression and activity in an enantiomer-specific way.

  8. Pgp (zeige ABCB4 Antikörper)-coupled ATPase (zeige DNAH8 Antikörper) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  9. Data show that human transgenic mutant huntingtin (zeige HTT Antikörper) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (zeige ABCB4 Antikörper)) which suggests that MDR1 (zeige ABCB4 Antikörper) might be a potential therapeutic target for Huntington's disease.

  10. In vitro and in vivo downregulation of the ATP binding cassette transporter (zeige ABCC3 Antikörper) B1 by the HMG-CoA reductase (zeige HMGCR Antikörper) inhibitor simvastatin

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antigen-Profil

Protein Überblick

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Genbezeichner und Symbole assoziert mit ABCB1B

  • ATP binding cassette subfamily B member 1 (ABCB1) Antikörper
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • ABC20 Antikörper
  • Abcb1 Antikörper
  • CD243 Antikörper
  • CLCS Antikörper
  • GP170 Antikörper
  • mdr Antikörper
  • Mdr1 Antikörper
  • Mdr1b Antikörper
  • P-GP Antikörper
  • Pgy-1 Antikörper
  • Pgy1 Antikörper

Bezeichner auf Proteinebene für ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPEZIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
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