anti-ATP Binding Cassette Transporter A3 (ABCA3) Antikörper

The membrane-associated protein encoded by ABCA3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ABCA3 Kits (4) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCA3 21 Q99758
ABCA3 27410 Q8R420
ABCA3 302973  
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Showing 10 out of 14 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
333,33 €
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Immunofluorescence analysis of HeLa cell using ABCA3 antibody. Blue: DAPI for nuclear staining. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: ABCA3 Antibody [NBP1-89310] - Staining of human lung shows trong cytoplasmic positivity in pneumocytes. Immunocytochemistry/Immunofluorescence: ABCA3 Antibody [NBP1-89310] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & cytoplasm. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
548,26 €
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Human Kaninchen Unkonjugiert WB Western blot testing of ABCA3 antibody and Lane 1:  rat brain;  2: human HeLa lysate.  Expected/observed size ~191KD 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
399,41 €
Details
Human Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 10 bis 12 Tage
433,02 €
Details
Human Kaninchen Unkonjugiert IF/ICC, IHC, WB   100 μL Anmelden zum Anzeigen 7 bis 12 Tage
386,31 €
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Ratte Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 10 bis 13 Tage
371,90 €
Details
Human Kaninchen Unkonjugiert EIA   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
357,50 €
Details

ABCA3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , ,


Mouse (Murine)


Rat (Rattus)


Weitere Antikörper gegen ABCA3 Interaktionspartner

Human ATP Binding Cassette Transporter A3 (ABCA3) Interaktionspartner

  1. two ABCA3 mutations (p.R288K and p.R1474W) identified among term and late-preterm infants with respiratory distress syndrome, were characterized.

  2. 1153 patients with diffuse parenchymal lung disease (DPLD (zeige PLD Antikörper)) were registered in the KLR (zeige KLRK1 Antikörper). The DNA of 242 of these patients was sequenced for ABCA3 mutations. 69 patients had at least one variation in the ABCA3 gene. Of 40 patients with two disease-causing ABCA3 mutations, 22 patients were homozygous and 18 heterozygous.

  3. Genes ABCC7 (zeige CFTR Antikörper), A3, A8, A12 (zeige UGT1A9 Antikörper), and C8 prevailed among the most upregulated or downregulated ones. In conclusion, the results supported our theory about general adenosine triphosphate-binding cassette gene expression profiles and their importance for cancer on clinical as well as research levels.

  4. transporter oligomerization is crucial for ABCA3 function.

  5. The TGGAG haplotype may be a risk factor for Respiratory Distress Syndrome in preterm infants in this Chinese population. The haplotype TGGAG was significantly more frequent in RDS (zeige PRPH2 Antikörper) infants than in non-RDS (zeige PRPH2 Antikörper) infants.

  6. Rare mutations in surfactant-associated genes contribute to neonatal respiratory distress syndrome. We resequenced all exons of the ATP-binding cassette member A3 (ABCA3) and we found three ABCA3 mutations in the Han [minor allele frequency (MAF (zeige MAF Antikörper))=0.003] and 7 in the Zhuang (MAF (zeige MAF Antikörper)=0.011) cohorts. The contribution of these rare ABCA3 mutations to disease burden in the south China population is still unknown.

  7. The clinical features of ABCA3 mutations, including onset, severity or clinical course are very heterogeneous. In the two siblings we had a lightly discordant course that could be explained by exposure to different environmental stresses or variable penetrance.

  8. These results provide evidence of ABCA3 as an MLF efflux transporter in human macrophages and support its role in the direct antileishmanial effect of this alkylphosphocholine drug.

  9. Studies indicate that ATP-binding cassette (ABC (zeige ABCB6 Antikörper)), subfamily A (zeige CYP Antikörper), member 3 (ABCA3) is developmentally regulated.

  10. Data discussed the structural features of ABCA3 and how the use of bioinformatics tools could help researchers to obtain a reliable structural model to locate relevant mutations and make genotype/phenotype correlations of affected patients. [review]

Mouse (Murine) ATP Binding Cassette Transporter A3 (ABCA3) Interaktionspartner

  1. Abca3 haploinsufficiency results in an altered biochemical and lung mechanical phenotype, as well as a greater lung injury induced by hyperoxia or mechanical ventilation.

  2. The majority of mice in which Abca3 was deleted in alveolar type II cells died shortly after birth from respiratory distress related to surfactant deficiency.

  3. Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter (zeige TAP2 Antikörper) protein (zeige LAPTM4A Antikörper) ABCA3

  4. showed for the first time expression and subcellular localization of abcb11 (zeige ABCB11 Antikörper) and abca3 in mouse kidney

  5. ABCA3 is necessary for lamellar body biogenesis, surfactant protein-B processing, and lung development late in gestation.

  6. The phenotype of respiratory failure immediately after birth corresponds to the clinical course of severe ABCA3 mutations in human newborns.

  7. Abca3 gene expression is mediated by discrete cis (zeige CISH Antikörper)-acting cassettes that mediate pulmonary cell- and lipid-sensitive pathways regulating surfactant homeostasis.

  8. Iportance of a functional catalytic cycle in lipid transport of ABCA3 suggestsa pathophysiological mechanism of pediatric intterstitial lung disease due to ABCA3 mutation.

ABCA3 Antigen-Profil

Protein Überblick

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death.

Genbezeichner und Symbole assoziert mit ABCA3

  • ATP-binding cassette, sub-family A (ABC1), member 3 (ABCA3) Antikörper
  • ATP-binding cassette, sub-family A (ABC1), member 3 (Abca3) Antikörper
  • ATP-binding cassette, subfamily A (ABC1), member 3 (Abca3) Antikörper
  • 1810036E22Rik Antikörper
  • ABC-C Antikörper
  • Abc3 Antikörper
  • EST111653 Antikörper
  • LBM180 Antikörper
  • SMDP3 Antikörper

Bezeichner auf Proteinebene für ABCA3

ABC transporter 3 , ABC-C transporter , ATP-binding cassette sub-family A member 3 , ATP-binding cassette transporter 3 , ATP-binding cassette, sub-family A (ABC1), member 3

GENE ID SPEZIES
21 Homo sapiens
27410 Mus musculus
302973 Rattus norvegicus
Ausgewählte Anbieter für anti-ABCA3 (ABCA3) Antikörper
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