APOBEC1 Complementation Factor Proteine (A1CF)

Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by A1CF. Zusätzlich bieten wir Ihnen A1CF Antikörper (49) und A1CF Kits (17) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
A1CF 29974 Q9NQ94
A1CF 69865 Q5YD48
A1CF 170912 Q923K9
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Showing 5 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,710.67
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$720.00
Details

A1CF Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu APOBEC1 Complementation Factor (A1CF) Interaktionspartnern

Human APOBEC1 Complementation Factor (A1CF) Interaktionspartner

  1. Study reported that the deleted 8aa, EIYMNVPV, was just localized in the internal region of A1CF nuclear translocation signal. Also, A1CF (-8aa), but not its full-length counterpart, can promote proliferation of MDA-MB-231 cells accompanied with increased level of IL-6 (zeige IL6 Proteine) mRNA.

  2. hnRNP K (zeige HNRNPK Proteine) and hnRNP L (zeige HNRNPL Proteine) may serve as A1CF-like cofactors in AID-mediated class switch recombination and somatic hypermutation

  3. The data presented in this report suggested that similar regulatory mechanisms controlling the functional interaction of APOBEC-1 (zeige APOBEC1 Proteine) with ACF might be operational during enterocyte differentiation.

  4. results suggested both AID and APOBEC-1 (zeige APOBEC1 Proteine) are equally likely to bind single-stranded DNA or RNA, which has implications for the identification of natural AID targets

  5. ACF plays a crucial role, which is independent of apobec-1 (zeige APOBEC1 Proteine) expression, in cell survival, particularly during early embryonic development

Mouse (Murine) APOBEC1 Complementation Factor (A1CF) Interaktionspartner

  1. The observations demonstrate that A1CF does not act as the APOBEC1 complementation factor in vivo under normal physiological conditions and suggest new roles for A1CF, specifically within the male adult kidney.

  2. Data show that the importance of ACF for modulating ApoB (zeige APOB Proteine) was supported by the finding that RNAi knockdown of ACF reduced ApoB (zeige APOB Proteine) secretion.

  3. ACF regulates liver regeneration following partial hepatectomy at least in part by controlling the stability of IL-6 (zeige IL6 Proteine) mRNA

  4. ACF plays a crucial role, which is independent of apobec-1 (zeige APOBEC1 Proteine) expression, in cell survival, particularly during early embryonic development

A1CF Protein Überblick

Protein Überblick

Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit A1CF

  • APOBEC1 complementation factor (A1CF)
  • APOBEC1 complementation factor (A1cf)
  • apobec1 complementation factor (a1cf)
  • APOBEC1 complementation factor L homeolog (a1cf.L)
  • APOBEC1 complementation factor (a1cf)
  • 1810073H04Rik Protein
  • A1CF Protein
  • A1cft Protein
  • acf Protein
  • acf64 Protein
  • acf65 Protein
  • Apobec-1 Protein
  • apobec1cf Protein
  • asp Protein

Bezeichner auf Proteinebene für A1CF

APOBEC-1 stimulating protein , apo-B RNA editing protein , apobec-1 complementation factor (ACF) (ASP) , APOBEC1-stimulating protein , apobec-1 complementation factor , APOBEC1 complementation factort , Apobec-1 complementation factor APOBEC-1 stimulating protein , Apobec-1 complementation factor, APOBEC-1 stimulating protein , acf , APOBEC1 complementation factor

GENE ID SPEZIES
29974 Homo sapiens
69865 Mus musculus
170912 Rattus norvegicus
423680 Gallus gallus
477581 Canis lupus familiaris
562916 Danio rerio
100174508 Pongo abelii
100339264 Oryctolagus cuniculus
444478 Xenopus laevis
703806 Macaca mulatta
100493284 Xenopus (Silurana) tropicalis
100540486 Meleagris gallopavo
100553455 Anolis carolinensis
100600191 Nomascus leucogenys
100336715 Bos taurus
100155074 Sus scrofa
100730935 Cavia porcellus
101118147 Ovis aries
Ausgewählte Anbieter für A1CF Proteine (A1CF)
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