AF4/FMR2 Family, Member 2 Proteine (AFF2)

AFF2 encodes a putative transcriptional activator that is a member of the AF4\FMR2 gene family. Zusätzlich bieten wir Ihnen AF4/FMR2 Family, Member 2 Antikörper (48) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
AFF2 2334 P51816
AFF2 14266 O55112
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Top AF4/FMR2 Family, Member 2 Proteine auf antikoerper-online.de

Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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AFF2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu AF4/FMR2 Family, Member 2 (AFF2) Interaktionspartnern

Human AF4/FMR2 Family, Member 2 (AFF2) Interaktionspartner

  1. Partial AFF2 microduplication in a patient with auditory processing disorder, emotional impairment and macrosomia.

  2. FMR2 is an upstream regulator of FOS and JUN (zeige JUN Proteine), and further link deregulation of the immediate early (zeige JUN Proteine) response genes to the pathology of ID- and FRAXE-associated ID in particular.

  3. 2.5% of males Autism spectrum disorder patients had missense mutations in AFF2 at highly conserved evolutionary sites.

  4. A report of novel deletions involving AFF2 provide evidence for a new mutational spectrum, microdeletions, that are responsible for Fragile X (zeige FMR1 Proteine) E in a small subset of patients.

  5. overexpression of AFF2/3/4 interferes with the organization and/or biogenesis of nuclear speckles.

  6. CGG/GCC (zeige GUCY2C Proteine) repeat polymorphism at the FMR1 (zeige FMR1 Proteine) and FMR2 loci observed in this study demonstrated a racial and ethnic variation among the populations in India.

  7. FMR1 (zeige FMR1 Proteine) transcripts were detected in foreskin and male fetal lung fibroblasts, while FMR2 transcripts were not. However, both FMR1 (zeige FMR1 Proteine) and FMR2 were found to replicate late in S phase (approximately 6 h into the S phase of normal human fibroblasts).

Mouse (Murine) AF4/FMR2 Family, Member 2 (AFF2) Interaktionspartner

  1. Overlapping expression of Af9 (zeige MLLT3 Proteine) with Af4/Aff1 and Fmr2/Aff2, two genes that are also related to neurodevelopmental diseases, as well as with the highly homologous Enl (zeige MLLT1 Proteine).

AF4/FMR2 Family, Member 2 (AFF2) Protein Überblick

Protein Überblick

This gene encodes a putative transcriptional activator that is a member of the AF4\FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit AFF2

  • AF4/FMR2 family, member 2 (AFF2)
  • AF4/FMR2 family, member 2 (Aff2)
  • Fmr2 Protein
  • FMR2P Protein
  • FRAXE Protein
  • MRX2 Protein
  • Ox19 Protein
  • Oxh Protein

Bezeichner auf Proteinebene für AFF2

AF4/FMR2 family member 2 , fragile X E mental retardation syndrome protein , fragile X mental retardation 2 protein , protein FMR-2 , Ox19 homolog , fragile X mental retardation 2 homolog , fragile X mental retardation protein 2 homolog , fragile X mental retardation 2

GENE ID SPEZIES
100434131 Pongo abelii
422394 Gallus gallus
2334 Homo sapiens
522215 Bos taurus
14266 Mus musculus
450122 Pan troglodytes
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