AE Binding Protein 1 Proteine (AEBP1)

The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. Zusätzlich bieten wir Ihnen AEBP1 Antikörper (47) und AEBP1 Kits (11) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
AEBP1 165 Q8IUX7
AEBP1 11568 Q640N1
Ratte AEBP1 AEBP1 305494 A2RUV9
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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AEBP1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu AE Binding Protein 1 (AEBP1) Interaktionspartnern

Human AE Binding Protein 1 (AEBP1) Interaktionspartner

  1. ACLP stimulates the fibroblast-to-myofibroblast transition by promoting SMA (zeige SMN1 Proteine) expression via TGFbeta (zeige TGFB1 Proteine) signaling and promoting collagen expression through a TGFbeta (zeige TGFB1 Proteine) receptor-independent pathway.

  2. There is no statistically significant differences in the frequency of variants in AEBP1 among the gastroschisis case group compared to a Caucasian control group.

  3. Most ACLP knockout mice die perinatally due to abdominal issues.

  4. Both cellular proliferation and survival were affected in AEBP1-silenced U87MG and U138MG cell lines and a significant percentage of these cells were directed towards apoptosis.

  5. This review focuses on the recently reported regulatory functions that adipocyte enhancer-binding protein 1 (AEBP1) exerts on PPARgamma1 and LXRalpha (zeige NR1H3 Proteine) transcriptional activity in the context of macrophage cholesterol homeostasis and inflammation.

  6. Transgenic overexpression of AEBP1 during adipogenesis coupled with a high-fat diet results in massive obesity in female transgenic mice via adipocyte hyperplasia.

  7. ACLP and its discoidin-like domain may be novel targets for anti-myofibroblast-based therapies for the treatment of pulmonary fibrosis.

Mouse (Murine) AE Binding Protein 1 (AEBP1) Interaktionspartner

  1. ACLP stimulates the fibroblast-to-myofibroblast transition by promoting SMA (zeige SMN1 Proteine) expression via TGFbeta (zeige TGFB1 Proteine) signaling and promoting collagen expression through a TGFbeta (zeige TGFB1 Proteine) receptor-independent pathway.

  2. Stromal adipocyte enhancer-binding protein (AEBP1) promotes mammary epithelial cell hyperplasia via proinflammatory and hedgehog (zeige SHH Proteine) signaling

  3. Data suggest that macrophage AEBP1 plays critical regulatory roles in atherogenesis, and it may serve as a potential therapeutic target for the prevention or treatment of atherosclerosis.

  4. Results describe the pathophysiological features of gastroschisis in aortic carboxypeptidase-like protein knockout mice and to characterize the neuromuscular development of the eviscerated intestine.

  5. MAPK (zeige MAPK1 Proteine) regulates the transcriptional activity of AEBP1 by a novel dual mechanism, in which MAPK (zeige MAPK1 Proteine) interaction enhances and subsequent phosphorylation decreases the DNA-binding ability of AEBP1

  6. AEBP1 plays critical regulatory roles in macrophage cholesterol homeostasis, foam cell formation, and proinflammation.

  7. NF-kappaB (zeige NFKB1 Proteine) activity is modulated by means of protein-protein interaction involving AEBP1 and IkappaBalpha (zeige NFKBIA Proteine).

  8. AEBP1 negatively regulates adipose tissue PTEN levels and has a key functional role in modulation of in vivo adiposity.

  9. Adipocyte enhancer-binding protein 1 (AEBP1) is up-regulated during monocyte differentiation.

  10. ACLP and its discoidin-like domain may be novel targets for anti-myofibroblast-based therapies for the treatment of pulmonary fibrosis.

AEBP1 Protein Überblick

Protein Überblick

The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. Adipocyte-enhancer binding protein 1 may play a role in differentiated vascular smooth muscle cells.

Genbezeichner und Symbole assoziert mit AE Binding Protein 1 Proteine (AEBP1)

  • AE binding protein 1 (Closa_4071)
  • AE binding protein 1 (AEBP1)
  • AE binding protein 1 (Aebp1)
  • ACLP Protein

Bezeichner auf Proteinebene für AE Binding Protein 1 Proteine (AEBP1)

AE binding protein 1 , adipocyte enhancer-binding protein 1 , aortic carboxypeptidase-like protein , AE-binding protein 1

GENE ID SPEZIES
9509393 Clostridium saccharolyticum WM1
165 Homo sapiens
733628 Sus scrofa
11568 Mus musculus
305494 Rattus norvegicus
317693 Bos taurus
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