ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) ELISA Kits

ADAMTS5 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Zusätzlich bieten wir Ihnen ADAMTS5 Antikörper (122) und ADAMTS5 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
ADAMTS5 23794 Q9R001
ADAMTS5 11096 Q9UNA0
ADAMTS5 304135  
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Top ADAMTS5 ELISA Kits auf antikoerper-online.de

Showing 10 out of 39 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.112 ng/mL 0.31-20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$589.47
Details
Maus 0.156 ng/mL 0.625-40 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details
Ratte 0.064 ng/mL 0.156-10 ng/mL 96 Tests Anmelden zum Anzeigen 15 bis 17 Tage
$973.11
Details
Rind (Kuh) 0.156 ng/mL 0.625-40 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,026.67
Details
Human 0.078 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$713.90
Details
Maus 15.6-1000 pg/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$713.90
Details
Kaninchen 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Hund 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Meerschweinchen 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Affe 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details

Am meisten referenzierte ADAMTS5 ELISA Kits

  1. Human ADAMTS5 ELISA Kit für Sandwich ELISA - ABIN649163 : Mern, Fontana, Beierfuß, Thomé, Hegewald et al.: A combinatorial relative mass value evaluation of endogenous bioactive proteins in three-dimensional cultured nucleus pulposus cells of herniated intervertebral discs: identification of potential ... in PLoS ONE 2013 (PubMed)
    Show all 6 Pubmed References

Weitere ELISA Kits für ADAMTS5 Interaktionspartner

Mouse (Murine) ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) Interaktionspartner

  1. Adamts5(-/-) mice were protected from hepatic mitochondrial dysfunction, as indicated by increased mitochondrial respiratory chain complex activity, higher ATP levels and higher expression of antioxidant enzymes. Absence of ADAMTS5 preserves liver integrity in a diet-induced obesity model.

  2. research emphasises the importance of ADAMTS5 expression in the control of influenza virus infection and highlights the potential for development of ADAMTS5-based therapeutic strategies to reduce morbidity and mortality

  3. TS5 protein functions to suppress glucose uptake in adipose-derived stromal cells and thereby inhibits the synthesis, and promotes the intracellular degradation of Acan (zeige ACAN ELISA Kits) and Vcan (zeige Vcan ELISA Kits) by an ADAMTS (zeige ADAMTS1 ELISA Kits) other than TS5.

  4. Data suggest that ADAMTS-5 oligomerization is required for full aggrecanase (zeige ADAMTS4 ELISA Kits) activity in vitro and in situ (as seen in knee joint of mouse model of inflammatory arthritis); thus, blocking oligomerization inhibits ADAMTS-5 activity.

  5. aggrecan (zeige ACAN ELISA Kits) and brevican (zeige BCAN ELISA Kits) proteolysis is compensated in Adamts4 (zeige ADAMTS4 ELISA Kits)-/- or Adamts5-/- mice by ADAMTS (zeige ADAMTS1 ELISA Kits) proteoglycanase (zeige MMP3 ELISA Kits) family members but a threshold of versican (zeige Vcan ELISA Kits) proteolysis is sensitive to the loss of a single ADAMTS (zeige ADAMTS1 ELISA Kits) proteoglycanase (zeige MMP3 ELISA Kits) during spinal cord injury

  6. The present study reveals ADAMT-5 expression by mast cells(MCs (zeige SMCP ELISA Kits)) and that MC activation regulates the expression of the protease, thus implicating the ADAMT-5 of protease in MC function.

  7. Western blot analyses indicated that aggrecanase (zeige ADAMTS4 ELISA Kits)-generated proteoglycan (zeige Vcan ELISA Kits) fragments are produced after SCI.

  8. RelA/p65 (zeige NFkBP65 ELISA Kits) is a potent transcriptional activator of ADAMTS5 in chondrocytes during osteoarthritis development.

  9. Repair of biomechanically compromised tendons exhibiting midsubstance chondroid accumulation requires ADAMTS5.

  10. this study identified, for the first time, several genes that have an ADAMTS-5-independent role in osteoarthritis(OA), identifying them as possible OA initiation candidates.

Human ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) Interaktionspartner

  1. The findings suggest that miR (zeige MLXIP ELISA Kits)-140 suppresses colorectal cancer progression and metastasis, possibly through downregulating ADAMTS5 and IGFBP5 (zeige IGFBP5 ELISA Kits).

  2. Results provide direct evidence indicating that Fibulin-2 (zeige FBLN2 ELISA Kits) is a novel substrate of ADAMTS-5 and that this proteolysis could alter the cellular microenvironment affecting the balance between protumor and antitumor effects associated to both Fibulin-2 (zeige FBLN2 ELISA Kits) and the ADAMTSs metalloproteases.

  3. Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritic chondrocytes, which manifested in increased expression of ADAMTS5, MMP13 (zeige MMP13 ELISA Kits), and decreased COL2A1 (zeige COL2A1 ELISA Kits) expression.

  4. Single Nucleotide Variants of Candidate Genes in Aggrecan (zeige ACAN ELISA Kits) Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes

  5. RREB1 (zeige RREB1 ELISA Kits) cooperates with noncoding RNA linc-ADAMTS5 to inhibit ADAMTS5 expression, thereby affecting degeneration of the extracellular matrix (ECM (zeige MMRN1 ELISA Kits)) of the intervertebral disc.

  6. Matrilin 2 (zeige MATN2 ELISA Kits) accumulation associated with relative ADAMTS5 deficiency may contribute to the mechanism underlying calcific aortic valve disease progression.

  7. In osteoarthritis (OA) chondrocytes, hydrostatic pressure (HP) restores the expression levels of some miRNAs, downregulates MMP-13 (zeige MMP13 ELISA Kits), ADAMTS-5, and HDAC-4 (zeige HDAC4 ELISA Kits), and modulates the Wnt (zeige WNT2 ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits) pathway activation.

  8. we investigated whether important polymorphisms in the ADAMTS4 (zeige ADAMTS4 ELISA Kits) and ADAMTS5 genes affect osteoarthritis (OA) susceptibility. ADAMTS4 (zeige ADAMTS4 ELISA Kits) and ADAMTS5 genotypes were determined using the ABI Prism StepOnePlus Real-Time system. Our findings suggest that the ADAMTS4 (zeige ADAMTS4 ELISA Kits) (rs4233367 and rs11807350) and ADAMTS5 (rs226794 and rs2830585) variants examined may not contribute to susceptibility to knee OA in the Turkish population.

  9. Increased ADAMTS5 levels were observed in placental insufficiency cases.

  10. ADAMTS5 protein levels in semen were significantly lower in males with infertility. Sperm count and motility showed a negative correlation with levels of ADAMTS5 protein expression.

Cow (Bovine) ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) Interaktionspartner

  1. The delayed activation of proMMPs and the relatively low cleavage efficiency of MMPs compared to ADAMTS5 (aggrecanase (zeige ADAMTS4 ELISA Kits)) explains the minor contribution of the MMP enzymes to aggrecan (zeige ACAN ELISA Kits) catabolism in vivo.

  2. ADAMTS4 (zeige ADAMTS4 ELISA Kits) and ADAMTS5 are inhibited by alpha2-macroglobulin (zeige A2M ELISA Kits)

  3. identified multiple conserved amino acids within regions N- and C-terminal to the site of scission that may influence enzyme-substrate recognition, and may interact with exosites on ADAMTS-4 (zeige ADAMTS4 ELISA Kits) and ADAMTS-5

  4. Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production.

ADAMTS5 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.

Genbezeichner und Symbole assoziert mit ADAMTS5

  • ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5) Antikörper
  • ADAM metallopeptidase with thrombospondin type 1 motif 5 (adamts5) Antikörper
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) (Adamts5) Antikörper
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5 (Adamts5) Antikörper
  • 9530092O11Rik Antikörper
  • ADAM-TS5 Antikörper
  • ADAM-TS 5 Antikörper
  • ADAM-TS 11 Antikörper
  • ADAMTS-5 Antikörper
  • ADAMTS-11 Antikörper
  • ADAMTS1 Antikörper
  • ADAMTS11 Antikörper
  • ADMP-2 Antikörper
  • AI481094 Antikörper
  • ASMP-2 Antikörper

Bezeichner auf Proteinebene für ADAMTS5

ADAM metallopeptidase with thrombospondin type 1 motif, 5 , a disintegrin and metalloproteinase with thrombospondin motifs 5-like , A disintegrin and metalloproteinase with thrombospondin motifs 5 , ADAM-TS 5 , ADAMTS-5 , ADMP-2 , aggrecanase-2 , implantin , a disintegrin and metalloproteinase with thrombospondin motifs 11 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) , ADAM-TS5 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)

GENE ID SPEZIES
100091913 Ornithorhynchus anatinus
100441162 Pongo abelii
100488158 Xenopus (Silurana) tropicalis
100552915 Anolis carolinensis
23794 Mus musculus
11096 Homo sapiens
100522952 Sus scrofa
286805 Bos taurus
304135 Rattus norvegicus
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