anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Antikörper

ADAMTS4 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Zusätzlich bieten wir Ihnen ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Kits (42) und ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ADAMTS4 240913 Q8BNJ2
ADAMTS4 9507 O75173
ADAMTS4 66015 Q9ESP7
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Top anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Antikörper auf antikoerper-online.de

Showing 10 out of 167 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-ADAMTS4 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>Host: </b>Rabbit<br><b>Target Name: </b>Adamts4<br><b>Antibody Dilution: </b>1.0ug/ml<br><b>Sample Tissue: </b>Rat Kidney Host: Rabbit <br /> Target Name: Adamts4 <br /> Antibody Dilution: 1.0 µg/mL <br /> Sample Tissue: Rat Kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of anti-ADAMTS4 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). ADAMTS4 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-ADAMTS4 Antibody (C-term) (ABIN391642) in mouse cerebellum tissue lysates (35 µg/lane). ADAMTS4 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Fledermaus Kaninchen Unkonjugiert IHC (p) Anti-ADAMTS4 antibody  ABIN1048291 IHC staining of human cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert WB Anti-ADAMTS4 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Brain Tissue Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-ADAMTS4 Polyclonal Antibody, Unconjugated (ABIN755173) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Fledermaus Kaninchen Unkonjugiert IHC (p) Human Heart (formalin-fixed, paraffin-embedded) stained with ADAMTS4 antibody ABIN625840 at 12 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Maus Kaninchen Unkonjugiert WB ADAMTS4 Polyclonal Antibody 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$313.50
Details

ADAMTS4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Antikörper

  1. Cow (Bovine) Polyclonal ADAMTS4 Primary Antibody für IHC, WB - ABIN2776877 : Lee, Hwang, Park, Lee, Park, Kang, Lee, Kim, Park, Park: Comparison of ADAMTS-1, -4 and -5 expression in culprit plaques between acute myocardial infarction and stable angina. in Journal of clinical pathology 2011 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal ADAMTS4 Primary Antibody für WB - ABIN391642 : Tortorella, Pratta, Liu, Abbaszade, Ross, Burn, Arner: The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Interaktionspartner

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Interaktionspartner

  1. the reduction of ADAMTS-4 activity during the progression of ALS pathology may be an adaptive change to mitigate its neurodegenerative impact in CNS tissues

  2. Results show that ADAMTS15 (zeige ADAMTS15 Antikörper) and ADAMTS4 not only exhibit unique cellular expression patterns in the brain but their developmental upregulation by these cell types coincides with critical aspects of neural development

  3. aggrecan (zeige ACAN Antikörper) and brevican (zeige BCAN Antikörper) proteolysis is compensated in Adamts4-/- or Adamts5 (zeige ADAMTS5 Antikörper)-/- mice by ADAMTS (zeige ADAMTS1 Antikörper) proteoglycanase (zeige MMP3 Antikörper) family members but a threshold of versican (zeige Vcan Antikörper) proteolysis is sensitive to the loss of a single ADAMTS (zeige ADAMTS1 Antikörper) proteoglycanase (zeige MMP3 Antikörper) during spinal cord injury

  4. ADAMTS4 has roles in melanoma growth and angiogenesis in mice

  5. The serine protease (zeige F2 Antikörper) tissue plasminogen activator (tPA (zeige PLAT Antikörper)) and two matrix metalloproteinases, ADAMTS-4 and ADAMTS-5 (zeige ADAMTS5 Antikörper), were identified as Reelin (zeige RELN Antikörper) cleaving enzymes.

  6. ADAMTS-4 cleaves Reelin (zeige RELN Antikörper) in an isoform-specific manner. Among ADAMTS-4 isoforms, p50 (zeige LSP1 Antikörper) cleaves the N-t site only, while p75 (zeige NGFR Antikörper) cleaves both sites.

  7. Data demonstrate that Adamts1 (zeige ADAMTS1 Antikörper) and Adamts4 play redundant and essential roles in perinatal kidney development.

  8. Drastic down-regulation of Adamts4 observed at both E16 (zeige SLC7A5 Antikörper) and E18; RT-PCR revealed post-natal reduction in expression (Adamts4, 1/3). Results suggest down-regulation of gene is important factor in normal odontogenesis in dental papillae.

  9. proteolysis of hevin by ADAMTS4 in the mouse cerebellum is important for the normal development of this tissue

  10. ADAMTS1 (zeige ADAMTS1 Antikörper), ADAMTS4, and ADAMTS5 (zeige ADAMTS5 Antikörper) are expressed in patterns that relate to the expression pattern of versican (zeige Vcan Antikörper) in granulosa cells of small follicles, expanded cumulus cell-oocyte complexes, and endothelial cells of the ovary.

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Interaktionspartner

  1. Using in vitro approaches and cultured breast cancer cell lines authors demonstrate that Fibulin-2 (zeige FBLN2 Antikörper) is a better substrate for ADAMTS-5 (zeige ADAMTS5 Antikörper) than it is for ADAMTS-4. Fibulin-2 (zeige FBLN2 Antikörper) degradation is associated to an enhancement of the invasive potential of T47D, MCF-7 and SK-BR-3 cells.

  2. ADAMTS4 and ADAMTS15 (zeige ADAMTS15 Antikörper) were upregulated in symptomatic uterine leiomyomas.

  3. The SNP rs4233367 in the exon of ADAMTS-4 gene may be associated with lumbar disc degeneration.

  4. Single Nucleotide Variants of Candidate Genes in Aggrecan (zeige ACAN Antikörper) Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes

  5. Results show that ADAMTS4 mRNA is the target of mir (zeige MLXIP Antikörper)-1268a and its expression might be modified by MIR (zeige MLXIP Antikörper)-1268a rs28599926 polymorphism in hepatocellular carcinoma.

  6. The pregnancy loss rate seems to be affected by both ADAMTS-3 and ADAMTS-16 (zeige ADAMTS16 Antikörper).

  7. we investigated whether important polymorphisms in the ADAMTS4 and ADAMTS5 (zeige ADAMTS5 Antikörper) genes affect osteoarthritis (OA) susceptibility. ADAMTS4 and ADAMTS5 (zeige ADAMTS5 Antikörper) genotypes were determined using the ABI Prism StepOnePlus Real-Time system. Our findings suggest that the ADAMTS4 (rs4233367 and rs11807350) and ADAMTS5 (zeige ADAMTS5 Antikörper) (rs226794 and rs2830585) variants examined may not contribute to susceptibility to knee OA in the Turkish population.

  8. ADAMTS4 expression is significantly upregulated in human masticatory mucosa during wound healing

  9. ADAMTS4 may have a role in the pathogenesis by causing increased oxidative and inflammatory environment in preterm premature rupture of membranes .

  10. in degenerative intervertebral discs, IL1b (zeige IL1B Antikörper) upregulates NFkB, MMP13 (zeige MMP13 Antikörper) and ADAMTS4

Horse (Equine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Interaktionspartner

  1. Studies suggest that miR (zeige MYLIP Antikörper)-140 is an important regulator of cartilage development and homeostasis in cord blood-derived mesenchymal stromal cells (eCB-MSCs) that may act, in part, through the regulation of CXCL12 (zeige CXCL12 Antikörper) and ADAMTS-5 (zeige ADAMTS5 Antikörper).

  2. ADAMTS5 (zeige ADAMTS5 Antikörper) is present in degenerative suspensory ligament desmitis as a high molecular weight complex

Rabbit ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Interaktionspartner

  1. a single injection of ADAMTS5 (zeige ADAMTS5 Antikörper) siRNA induced the suppression of degradation in rabbit nucleus pulposus tissues

Cow (Bovine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Interaktionspartner

  1. ADAMTS4 participates in the regulation of muscle development in cattle.

  2. aggrecanase activity (a) is responsible for early TNFalpha (zeige TNF Antikörper)-dependent aggrecan (zeige ACAN Antikörper) cleavage and GAG release in the meniscus and (b) might be involved in meniscal degeneration.

  3. ADAMTS4 and ADAMTS5 (zeige ADAMTS5 Antikörper) are inhibited by alpha2-macroglobulin (zeige A2M Antikörper)

  4. identified multiple conserved amino acids within regions N- and C-terminal to the site of scission that may influence enzyme-substrate recognition, and may interact with exosites on ADAMTS-4 and ADAMTS-5 (zeige ADAMTS5 Antikörper)

ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Antigen-Profil

Protein Überblick

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.

Genbezeichner und Symbole assoziert mit ADAMTS4

  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4) Antikörper
  • ADAM metallopeptidase with thrombospondin type 1 motif 4 (ADAMTS4) Antikörper
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4 (Adamts4) Antikörper
  • ADAMTS like 4 (ADAMTSL4) Antikörper
  • ADAM metallopeptidase with thrombospondin type 1 motif 4 (Adamts4) Antikörper
  • 3830423K05 Antikörper
  • ADAM-TS4 Antikörper
  • ADAMTS-2 Antikörper
  • ADAMTS-4 Antikörper
  • ADAMTS4 Antikörper
  • ADMP-1 Antikörper
  • mKIAA0688 Antikörper

Bezeichner auf Proteinebene für ADAMTS4

A disintegrin and metalloproteinase with thrombospondin motifs 4 , ADAM-TS 4 , ADAMTS-4 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4 , aggrecanase-1 , ADAM-TS4 , Aggrecanase , a disintegrin and metallopeptidase with thrombospondin motifs 4 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 , ADMP-1 , ADAM metallopeptidase with thrombospondin type 1 motif, 4 , A disintegrin and metalloproteinase with thrombospondin motifs 4-like , disintegrin and metalloproteinase with thrombospondin motifs 2 , a disintegrin and metalloproteinase with thrombospondin motifs 4

GENE ID SPEZIES
240913 Mus musculus
9507 Homo sapiens
66015 Rattus norvegicus
286806 Bos taurus
457453 Pan troglodytes
488651 Canis lupus familiaris
719927 Macaca mulatta
100033914 Equus caballus
100409334 Callithrix jacchus
100008765 Oryctolagus cuniculus
100482466 Ailuropoda melanoleuca
100606067 Nomascus leucogenys
100514576 Sus scrofa
100712995 Cavia porcellus
101106565 Ovis aries
100461178 Pongo abelii
Ausgewählte Anbieter für anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Antikörper
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