ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) ELISA Kits

ADAMTS13 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Zusätzlich bieten wir Ihnen ADAMTS13 Antikörper (100) und ADAMTS13 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
ADAMTS13 279028 Q769J6
ADAMTS13 11093 Q76LX8
ADAMTS13 362091  
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Top ADAMTS13 ELISA Kits auf antikoerper-online.de

Showing 10 out of 33 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.127 ng/mL 0.31-20 ng/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
421,59 €
Details
Ratte 15.6 pg/mL 62.5-4000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
772,39 €
Details
Maus 19.5 pg/mL 78-5000 pg/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
772,39 €
Details
Human 0.33 ng/mL 0.78-50 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
528,00 €
Details
Maus 78-5000 pg/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
653,71 €
Details
Kaninchen 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details
Meerschweinchen 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details
Affe 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details
Hund 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details
Schwein
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details

Am meisten referenzierte ADAMTS13 ELISA Kits

  1. Human ADAMTS13 ELISA Kit für Sandwich ELISA - ABIN417448 : Tati, Kristoffersson, Manea Hedström, Mörgelin, Wieslander, van Kooten, Karpman: Neutrophil Protease Cleavage of Von Willebrand Factor in Glomeruli - An Anti-thrombotic Mechanism in the Kidney. in EBioMedicine 2017 (PubMed)

Weitere ELISA Kits für ADAMTS13 Interaktionspartner

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) Interaktionspartner

  1. results suggest that ADAMTS13 controls key steps of ischemic vascular remodeling and that recombinant ADAMTS13 is a putative therapeutic avenue for promoting stroke recovery.

  2. ADAMTS13 retards progression of diabetic nephropathy, most likely by inhibiting VWF (zeige VWF ELISA Kits)-dependent intrarenal thrombosis.

  3. administration of ADAMTS13 5 minutes after occlusion dose-dependently dissolved these t-PA-resistant thrombi resulting in fast restoration of MCA patency and consequently reduced cerebral infarct sizes

  4. Sleeping beauty transposon-mediated gene therapy achieved sustained expression of transgene ADAMTS13 and long-term prophylaxis against congenital thrombotic thrombocytopenic purpura in Adamts13(-/-) mice.

  5. Results also suggest that Toxoplasma gondii-mediated apoptosis might play a pivotal role and a different type of role in the mechanism of neurodegeneration and neuropathology in the process of toxoplasma encephalitis. Furthermore, expression of ADAMTS-13 might give an idea of the progress and is critical for diagnosis of this disease.

  6. Letter: deficiency of ADAMTS13 results in increased formation of venous thrombosis in mice.

  7. ADAMTS13 substrate specificity

  8. Data indicate that the p.D187H mutation impairs ADAMTS13 activity and secretion and may contribute to thrombotic thrombocytopenic purpura.

  9. Data show that metalloendopeptidase (zeige THOP1 ELISA Kits) ADAMTS13 does not directly promote development of adipose tissue.

  10. findings provide further evidence on the pathophysiological role for the ADAMTS13/VWF (zeige VWF ELISA Kits) axis in atherosclerosis

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) Interaktionspartner

  1. both in acute and chronic cerebrovascular disease patients, ADAMTS13 levels were significantly decreased, with the lowest ADAMTS13 levels found in acute stroke patients. This difference was even more distinct when the ratio of VWF:ADAMTS13 was considered. These results demonstrate the potentially important involvement of the VWF (zeige VWF ELISA Kits)/ADAMTS13 axis in ischemic stroke.

  2. Placental trophoblasts and villous vessel endothelial cells produce a full-length and functional ADAMTS13 protease. Placental expression of ADAMTS13 exhibits a dynamic change during pregnancy, which seems to be inhibited in late pregnancy and in patients with severe preeclampsia.

  3. ADAMTS13 activity appears to be an independent risk factor for incident prediabetes and type 2 diabetes.

  4. both anti-ADAMTS13 IgG antibody and ADAMTS13 antigen levels correlate with outcome in thrombotic thrombocytopenic purpura with increased cardiac and neurological involvement and increased mortality.

  5. Low ADAMTS-13 levels correlated with high levels of NTproBNP but had no independent prognostic significance. In conclusion, high VWF:Ag levels, probably representing endothelial dysfunction, are associated with prognosis in patients with AL amyloidosis, independently of other features of the disease or cardiac biomarkers.

  6. findings highlight the complexity of glycan modifications on ADAMTS13, which may have implications for its interaction with immune- or clearance receptors containing carbohydrate recognition domains.

  7. ADAMTS-13 levels are decreased in plasma of AML (zeige RUNX1 ELISA Kits) patients and the level of ADAMTS-13 is related to inflammation and infection of AML (zeige RUNX1 ELISA Kits) patients. Besides, low ADAMTS-13 level is one potential risk factor for AML (zeige RUNX1 ELISA Kits)

  8. these results demonstrate that HNPs1-3 may be potent inhibitors of ADAMTS13 activity, likely by binding to the central A2 domain of VWF (zeige VWF ELISA Kits) and physically blocking ADAMTS13 binding.

  9. Three Single Nucleotide Variants (p.Val154Ile, p.Asp187His and p.Arg421Cys) showed reduced ex vivo and in vitro ADAMTS13 levels. However, the low frequency of these variants makes it difficult to confirm their association with Deep Vein Thrombosis.

  10. ADAMTS13 activity and VWF:Ag levels are both associated with an increased risk of all-cause and cardiovascular mortality.

ADAMTS13 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit ADAMTS13

  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13) Antikörper
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (adamts13) Antikörper
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (LOC100226372) Antikörper
  • ADAM metallopeptidase with thrombospondin type 1 motif, 12 (ADAMTS12) Antikörper
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 (Adamts13) Antikörper
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (Adamts13) Antikörper
  • ADAM-TS13 Antikörper
  • ADAMTS-13 Antikörper
  • ADAMTS12 Antikörper
  • ADAMTS13 Antikörper
  • C9orf8 Antikörper
  • Gm710 Antikörper
  • vWF-CP Antikörper
  • VWFCP Antikörper

Bezeichner auf Proteinebene für ADAMTS13

ADAM metallopeptidase with thrombospondin type 1 motif, 13 , ADAM metallopeptidase with thrombospondin type 1 motif, 13 isoform 1 preproprotein-like , A disintegrin and metalloproteinase with thrombospondin motifs 13-like , ADAM metallopeptidase with thrombospondin type 1 motif, 12 , A disintegrin and metalloproteinase with thrombospondin motifs 12 , A disintegrin and metalloproteinase with thrombospondin motifs 13 , ADAM-TS 13 , ADAM-TS13 , ADAMTS-13 , ADAMTS13 isoform IAP-b , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 , vWF-CP mRNA for von Willebrand factor-cleaving , vWF-cleaving protease , von Willebrand factor-cleaving protease , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

GENE ID SPEZIES
100069281 Equus caballus
100320289 Danio rerio
100404947 Callithrix jacchus
100481099 Ailuropoda melanoleuca
100226372 Taeniopygia guttata
427428 Gallus gallus
461952 Pan troglodytes
479369 Canis lupus familiaris
525276 Bos taurus
701750 Macaca mulatta
100068281 Equus caballus
279028 Mus musculus
11093 Homo sapiens
100630922 Canis lupus familiaris
532272 Bos taurus
362091 Rattus norvegicus
100343027 Oryctolagus cuniculus
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