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NT5C3 encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. Zusätzlich bieten wir Ihnen 5'-Nucleotidase, Cytosolic III Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.
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Mouse (Murine) Monoclonal NT5C3 Primary Antibody für IF, IP - ABIN968020
Fisher, Jin, Chamberlin, Morgan: Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase. in Cell 1995
Show all 3 Pubmed References
Human Polyclonal NT5C3 Primary Antibody für IHC, IHC (p) - ABIN4340799
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
polymerization of the Phc2 (zeige PhC2 Antikörper) SAM (zeige TTN Antikörper) domain is required for PRC1 (zeige PRC1 Antikörper) clustering, chromatin condensation and gene silencing.
Phc2 (zeige PhC2 Antikörper) may act as a negative regulator that inhibits the activity of Th cells.
report describes the first X-ray structure of a catalytically inactivated variant of murine cN-III with a natural substrate, uridine 5'-monophosphate, in the active site at 1.74A resolution
functional overlap between Phc2 (zeige PhC2 Antikörper) and Phc1 (zeige PHC1 Antikörper) along with a strict dose-dependent requirement during anterior-posterior (A-P) patterning
reduced expression of transketolase (zeige TKT Antikörper) in pyrimidine 5'-nucleotidase (zeige NT5E Antikörper) deficient patients
Pyrimidine-5'-nucleotidase (zeige NT5E Antikörper) Campinas is a new mutation (p.R56G) in the NT5C3 gene associated with pyrimidine-5'-nucleotidase (zeige NT5E Antikörper) type I deficiency.
Results show that NT5C3 expression levels were significantly increased in patients with risk allele homozygote.
New missense homozygous mutation (Q270Ter) in the pyrimidine 5' nucleotidase (zeige NT5E Antikörper) type I-related gene in two Indian families with hereditary non-spherocytic hemolytic anemia.
analysis of Drosophila and human 7-methyl GMP (zeige NT5C2 Antikörper)-specific nucleotidases
Data show that PN-I (zeige NT5C Antikörper) shows a higher affinity for oxynucleosides rather than deoxynucleosides, while the opposite is true for PN-II (zeige APP Antikörper).
These data highlight hUMP1/POMP (zeige POMP Antikörper) role in proteasome assembly and further strengthen the prospect of genetic manipulation of the proteasomal system.
In leukoblasts from 82 patients with acute myeloid leukemia (zeige BCL11A Antikörper), various extent and frequency of differential allelic expression in the CDA (zeige CDA Antikörper), DCK (zeige DCK Antikörper), NT5C2 (zeige NT5C2 Antikörper), NT5C3, and TP53 (zeige TP53 Antikörper) genes was observed.
genetic variation in NT5C3 might affect protein function and potentially influence drug response
This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4.
5'-nucleotidase, cytosolic III
, cytosolic 5'-nucleotidase 3
, cytosolic 5'-nucleotidase 3A
, cytosolic 5'-nucleotidase III
, pyrimidine 5'-nucleotidase 1
, 5'-nucleotidase, pyrimidine
, uridine monophosphatase 1
, uridine 5'-monophosphate hydrolase 1
, early development regulator 2
, early development regulatory protein 2
, polyhomeotic 2 protein
, polyhomeotic-like protein 2