5'-Nucleotidase, Cytosolic II Proteine (NT5C2)

NT5C2 encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. Zusätzlich bieten wir Ihnen 5'-Nucleotidase, Cytosolic II Antikörper (56) und 5'-Nucleotidase, Cytosolic II Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NT5C2 22978 P49902
NT5C2 76952 Q3V1L4
NT5C2 100363253  
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Top 5'-Nucleotidase, Cytosolic II Proteine auf antikoerper-online.de

Showing 8 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$319.00
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 20 Days
$785.40
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$413.21
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Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$432.00
Details
Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$312.71
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NT5C2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , ,
Mouse (Murine) ,

Rat (Rattus)

Weitere Proteine zu 5'-Nucleotidase, Cytosolic II (NT5C2) Interaktionspartnern

Human 5'-Nucleotidase, Cytosolic II (NT5C2) Interaktionspartner

  1. acute lymphoblastic leukemia-specific mutations affect regulation of cN-II

  2. this study implicates altered neural expression of BORCS7, AS3MT (zeige AS3MT Proteine), and NT5C2 in susceptibility to schizophrenia arising from genetic variation at the chromosome 10q24 locus

  3. NT5C2 variant rs11191580 conferred susceptibility to schizophrenia and affected the clinical symptoms of schizophrenia in a South Chinese Han population.

  4. The aberrantly spliced NT5C2 showed substantial reduction in expression level in the in-vitro study, indicating marked instability of the mutant NT5C2 protein.

  5. Leukemia Relapse-Associated Mutation of NT5C2 Gene is Rare in de Novo Acute Leukemias and Solid Tumors.

  6. cN-II co-immunoprecipitated both with wild type Ipaf (zeige NLRC4 Proteine) and its LRR domain after transfection with corresponding expression vectors, but not with Ipaf (zeige NLRC4 Proteine) lacking the LRR domain.

  7. Data indicate that type II cytosolic 5'-nucleotidase (zeige NT5E Proteine) (cN-II) exerts a role in nucleotide and drug metabolism and regulating cell survival.

  8. Four novel body mass index-associated loci near the KCNQ1 (zeige KCNQ1 Proteine)(rs2237892), ALDH2 (zeige ALDH2 Proteine)/MYL2 (zeige MYL2 Proteine) (rs671, rs12229654), ITIH4 (zeige ITIH4 Proteine) (rs2535633) and NT5C2 (rs11191580) genes are identified in East Asian-ancestry populations.

  9. These results suggest that mutations in NT5C2 are associated with the outgrowth of drug-resistant clones in acute lymphoblastic leukemia

  10. results highlight the prominent role of relapse-specific mutations in NT5C2 as a mechanism of resistance to 6-Mercaptopurine and a genetic driver of relapse in acute lymphoblastic leukemia

Mouse (Murine) 5'-Nucleotidase, Cytosolic II (NT5C2) Interaktionspartner

  1. The results on muscles from the NT5C (zeige NT5C Proteine) knockout mice contradict previous findings where AMP (zeige TMPRSS5 Proteine) levels and AMPK (zeige PRKAA1 Proteine) activity were shown to be modulated by NT5C (zeige NT5C Proteine) enzymes.

Cow (Bovine) 5'-Nucleotidase, Cytosolic II (NT5C2) Interaktionspartner

  1. mutated three residues that mediate interaction in the first activation site (R144, N154, I152) and three in the second (F127, M436 and H428), and found that ApA and ADP interact with the same site, but the sites for ATP and BPG remain uncertain

5'-Nucleotidase, Cytosolic II (NT5C2) Protein Überblick

Protein Überblick

This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides.

Genbezeichner und Symbole assoziert mit NT5C2

  • 5'-nucleotidase, cytosolic II (NT5C2)
  • 5'-nucleotidase, cytosolic II (nt5c2.L)
  • 5'-nucleotidase, cytosolic II (nt5c2)
  • 5'-nucleotidase, cytosolic IIa (nt5c2a)
  • 5'-nucleotidase, cytosolic II (Nt5c2)
  • 5'-nucleotidase, cytosolic II (surE2)
  • 2010002I23Rik Protein
  • cN-II Protein
  • CnII Protein
  • ENSMUSG00000025039 Protein
  • Gm9751 Protein
  • Gmp Protein
  • Nt5b Protein
  • NT5C2 Protein
  • Pnt5 Protein
  • wu:fc36f11 Protein
  • wu:fc45b10 Protein

Bezeichner auf Proteinebene für NT5C2

cytosolic 5'-nucleotidase II , cytosolic purine 5'-nucleotidase , 5'-nucleotidase, cytosolic II , fc36f11 , 5'-nucleotidase (purine), cytosolic type B , IMP-specific 5'-NT , purine 5' nucleotidase , 5'-nucleotidase cytosolic II , cytosolic IMP/GMP-specific 5'-nucleotidase , cytosolic purine 5'-nucleotidase-like

GENE ID SPEZIES
477809 Canis lupus familiaris
444729 Xenopus laevis
548490 Xenopus (Silurana) tropicalis
714292 Macaca mulatta
324845 Danio rerio
22978 Homo sapiens
450706 Pan troglodytes
76952 Mus musculus
281951 Bos taurus
423871 Gallus gallus
100172749 Pongo abelii
5808749 Sorangium cellulosum So ce56
100363253 Rattus norvegicus
100402763 Callithrix jacchus
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