anti-5'-3' Exoribonuclease 2 (XRN2) Antikörper

XRN2 shares similarity with the mouse Dhm1 and the yeast dhp1 gene. Zusätzlich bieten wir Ihnen XRN2 Kits (3) und XRN2 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
XRN2 22803 Q9H0D6
XRN2 24128 Q9DBR1
XRN2 362229  
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Top anti-XRN2 Antikörper auf antikoerper-online.de

Showing 10 out of 42 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB XRN2 Antibody (N-term) (ABIN658280) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the XRN2 antibody detected the XRN2 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Western Blot and Immunoprecipitation: XRN2 Antibody [ABIN252879] - Detection of Human XRN2 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- XRN2 antibody ABIN252879 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. XRN2 was also immunoprecipitated by another rabbit anti-XRN2 antibody, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 seconds (A) and 10 seconds (B). Western Blot: XRN2 Antibody [ABIN2528791] - Detection of Mouse : Whole cell lysate (50 ug) from TCMK-1, 4T1, and CT26.WT cells. Antibodies: Affinity purified rabbit anti-XRN2 antibody used for WB at 0.4 ug/ml.Detection: Chemiluminescence with an exposure time of 3 minutes. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Huhn Kaninchen Unkonjugiert IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
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Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert WB Western Blot and Immunoprecipitation: XRN2 Antibody [ABIN252877] - Detection of Human and Mouse XRN2 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-XRN2 antibody ABIN252877 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B). XRN2 was immunoprecipitated by another rabbit anti-XRN2 antibodies  and ABIN252879, which recognize downstream epitopes. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B). 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert WB Western Blot and Immunoprecipitation: XRN2 Antibody [ABIN252878] - Detection of Human and Mouse XRN2 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-XRN2 antibody ABIN252878 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B). XRN2 was immunoprecipitated by another rabbit anti-XRN2 antibody and ABIN252879, which recognize downstream epitopes.  Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 seconds (B). 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA, WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
565,71 €
Details
Human Maus Unkonjugiert ELISA, IHC, WB   0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
550,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF Immunocytochemistry/Immunofluorescence: XRN2 Antibody  - Staining of human cell line MCF7 shows localization to nucleus & nucleoli. 100 μL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert ELISA, WB XRN2 antibody western blot analysis in T47D lysate 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
417,74 €
Details

XRN2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-XRN2 Antikörper

  1. Human Polyclonal XRN2 Primary Antibody für ICC, IF - ABIN252879 : Barnhart, Moon, Emch, Wilusz, Wilusz: Changes in cellular mRNA stability, splicing, and polyadenylation through HuR protein sequestration by a cytoplasmic RNA virus. in Cell reports 2013 (PubMed)

Weitere Antikörper gegen XRN2 Interaktionspartner

Human 5'-3' Exoribonuclease 2 (XRN2) Interaktionspartner

  1. depletion of NKRF (zeige NKRF Antikörper), XRN2 or DHX15 (zeige DHX15 Antikörper) impairs an early pre-rRNA cleavage step.

  2. XRN2 is a novel regulator of EMT (zeige ITK Antikörper) that contributes to the metastatic processes in lung cancer through a novel miRNA regulatory mechanism.

  3. XRN2 has a role in R-loop resolution, suppression of replication stress, and maintenance of genomic stability

  4. Chromatin immunoprecipitation experiments further show that IL-1 (zeige IL1A Antikörper) stimulation leads to decrease in NKRF (zeige NKRF Antikörper) aa 421-429 phosphorylation and dissociation of NELF-E (zeige RDBP Antikörper) and XRN2 by concomitant resumption of transcription elongation of a synthetic reporter

  5. P-TEFb (zeige CCNT1 Antikörper) regulates termination by promoting chromatin recruitment and activation of a cotranscriptional RNA processing enzyme, Xrn2.

  6. The results suggest that CARF (zeige CDKN2AIP Antikörper) regulates early steps of pre-rRNA processing during ribosome biogenesis by controlling spatial distribution of XRN2 between the nucleoplasm and nucleolus.

  7. Kinetic competition between elongating pol II and the Xrn2 exonuclease (zeige EXO1 Antikörper) is integral to termination of transcription on most human genes.

  8. found that the 3' fragments of target pre-mRNA generated by ASO were almost completely degraded from their 5' ends by nuclear XRN2 after RNase H1 (zeige RNASEH1 Antikörper)-mediated cleavage

  9. The restriction of JFH1 and H77D hepatitis C virus replication by Xrn2 is likely indirect in nature and possibly linked to cytopathic effects of these robustly replicating viruses.

  10. Xrn2 has a cytoplasmic, antiviral function against HCV that is counteracted by HCV's subversion of miR (zeige MLXIP Antikörper)-122 to form a protective oligomeric complex at the 5' end of the viral genome.

Mouse (Murine) 5'-3' Exoribonuclease 2 (XRN2) Interaktionspartner

  1. Genetic variants regulating Xrn2 expression in cis (zeige CISH Antikörper) are determinants of spontaneous lung tumor susceptibility in mice and have genetic equivalents in lung cancer susceptibility in human beings.

Arabidopsis thaliana 5'-3' Exoribonuclease 2 (XRN2) Interaktionspartner

  1. AtXRN2 has a role in ribosomal RNA processing.

  2. The nuclear exoribonucleases XRN2 and XRN3 the nucleotidase/phosphatase FIERY1 (zeige SAL1 Antikörper) are endogenous posttranscriptional gene silencing suppressors.

XRN2 Antigen-Profil

Protein Überblick

This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene\; however, their full-length nature is not known.

Genbezeichner und Symbole assoziert mit XRN2

  • 5'-3' exoribonuclease 2 (xrn2) Antikörper
  • 5'-3' exoribonuclease 2 (XRN2) Antikörper
  • 5'-3' exoribonuclease 2 (TA11675) Antikörper
  • 5'-3' exoribonuclease 2 (LELG_04162) Antikörper
  • 5'-3' exoribonuclease 2 (AOR_1_874194) Antikörper
  • 5'-3' exoribonuclease 2 (PTRG_01514) Antikörper
  • 5'-3' exoribonuclease 2 (PTRG_10866) Antikörper
  • 5'-3' exoribonuclease 2 (Tsp_08094) Antikörper
  • 5'-3' exoribonuclease 2 (LOC100353161) Antikörper
  • 5'-3' exoribonuclease 2 (Xrn2) Antikörper
  • AO090012000503 Antikörper
  • AtXRN2 Antikörper
  • DKFZp459J063 Antikörper
  • exoribonuclease 2 Antikörper
  • K16E1.2 Antikörper
  • K16E1_2 Antikörper
  • wu:fb38g12 Antikörper
  • wu:fj53d06 Antikörper
  • zgc:55717 Antikörper

Bezeichner auf Proteinebene für XRN2

5'-3' exoribonuclease 2 , 5'-3' exoribonuclease 2-like , DHP protein , Dhm1-like protein (mouse homolog) , protein Dhm1

GENE ID SPEZIES
321940 Danio rerio
458131 Pan troglodytes
477133 Canis lupus familiaris
517417 Bos taurus
700934 Macaca mulatta
733834 Xenopus (Silurana) tropicalis
3861687 Theileria annulata strain Ankara
5231754 Lodderomyces elongisporus NRRL YB-4239
5987983 Aspergillus oryzae RIB40
6338441 Pyrenophora tritici-repentis Pt-1C-BFP
6349178 Pyrenophora tritici-repentis Pt-1C-BFP
10906655 Trichinella spiralis
100031372 Monodelphis domestica
100049102 Xenopus laevis
100050094 Equus caballus
100173960 Pongo abelii
100353161 Oryctolagus cuniculus
100388181 Callithrix jacchus
100468930 Ailuropoda melanoleuca
100517201 Sus scrofa
100593111 Nomascus leucogenys
22803 Homo sapiens
24128 Mus musculus
362229 Rattus norvegicus
421236 Gallus gallus
834261 Arabidopsis thaliana
Ausgewählte Anbieter für anti-XRN2 (XRN2) Antikörper
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